| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.288722 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.124828 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0652374 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0616074 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0610147 |
| EHBP1 | EH domain binding protein 1 | 0.0556692 |
| NPSR1 | neuropeptide S receptor 1 | 0.0516031 |
| VEGFA | vascular endothelial growth factor A | 0.0505675 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0493515 |
| KLHL29 | kelch-like family member 29 | 0.0465139 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0458316 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0451793 |
| H1-0 | H1.0 linker histone | 0.0422707 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0397214 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0392261 |
| CDK6 | cyclin-dependent kinase 6 | 0.0376481 |
| FAT1 | FAT atypical cadherin 1 | 0.0353169 |
| RUNX1 | runt-related transcription factor 1 | 0.0349673 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034554 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0343584 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334926 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0330391 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0314364 |
| ATXN1 | ataxin 1 | 0.0308554 |
| AREG | amphiregulin | 0.0308003 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0306655 |
| FLNB | filamin B, beta | 0.0297099 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0291689 |
| CANX | calnexin | 0.0291239 |
| NDRG1 | N-myc downstream regulated 1 | 0.029072 |
| RPS3 | ribosomal protein S3 | 0.0285202 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278905 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0271576 |
| AHNAK | AHNAK nucleoprotein | 0.0271378 |
| ITGA6 | integrin, alpha 6 | 0.026534 |
| RPL35A | ribosomal protein L35a | 0.0262828 |
| AOPEP | aminopeptidase O (putative) | 0.0258837 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0258534 |
| AGR2 | anterior gradient 2 | 0.0257064 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0256065 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0247788 |
| GOLGA4 | golgin A4 | 0.0244882 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0243374 |
| HM13 | histocompatibility (minor) 13 | 0.0243323 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0241602 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0241031 |
| ANXA2 | annexin A2 | 0.023457 |
| RPN1 | ribophorin I | 0.0233561 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0227869 |
| HLA-C | major histocompatibility complex, class I, C | 0.0227629 |
| COG5 | component of oligomeric golgi complex 5 | 0.022753 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0222876 |
| PMM2 | phosphomannomutase 2 | 0.0221467 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0219788 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0219753 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0215575 |
| FAM135A | family with sequence similarity 135, member A | 0.0214854 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0213796 |
| RPL37A | ribosomal protein L37a | 0.0213382 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0208887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.020283 |
| RPS12 | ribosomal protein S12 | 0.0201461 |
| KIF16B | kinesin family member 16B | 0.0201029 |
| SHROOM3 | shroom family member 3 | 0.0200072 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0198877 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0198046 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0197754 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0196897 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0196772 |
| LAMB3 | laminin, beta 3 | 0.0196572 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0195489 |
| ANXA1 | annexin A1 | 0.019438 |
| GOLGB1 | golgin B1 | 0.019403 |
| PGK1 | phosphoglycerate kinase 1 | 0.0193671 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.019212 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0191059 |
| CDK13 | cyclin-dependent kinase 13 | 0.0189635 |
| AFDN | afadin, adherens junction formation factor | 0.0187442 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0185745 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0184314 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0183235 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0182613 |
| RPL38 | ribosomal protein L38 | 0.0181298 |
| FRMD5 | FERM domain containing 5 | 0.0181261 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0181234 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.01799 |
| PATJ | PATJ crumbs cell polarity complex component | 0.017902 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0178858 |
| SETD5 | SET domain containing 5 | 0.0178758 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.017643 |
| RAD51B | RAD51 paralog B | 0.0176206 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0175108 |
| EXOC6B | exocyst complex component 6B | 0.0174622 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0172556 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0171228 |
| CCNY | cyclin Y | 0.0170465 |
| RPS8 | ribosomal protein S8 | 0.0169427 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0168823 |
| PGM3 | phosphoglucomutase 3 | 0.0168645 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0167948 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0975081 |
| TMSB10 | thymosin beta 10 | -0.0681007 |
| FTL | ferritin, light polypeptide | -0.0594996 |
| POTEF | POTE ankyrin domain family, member F | -0.0565268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0564864 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0422341 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0408065 |
| EZR | ezrin | -0.0371325 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.034014 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321383 |
| RPL23 | ribosomal protein L23 | -0.0312863 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0302283 |
| S100A10 | S100 calcium binding protein A10 | -0.028678 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0281388 |
| S100A6 | S100 calcium binding protein A6 | -0.0268444 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0261271 |
| PERP | PERP, TP53 apoptosis effector | -0.0250026 |
| CBX3 | chromobox homolog 3 | -0.0245903 |
| UBC | ubiquitin C | -0.0244558 |
| B2M | beta-2-microglobulin | -0.0240876 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0240706 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0235342 |
| LYZ | lysozyme | -0.0228166 |
| KRT19 | keratin 19, type I | -0.0222858 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0219769 |
| CLDN4 | claudin 4 | -0.021623 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.021247 |
| TUBA1B | tubulin, alpha 1b | -0.0198251 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0195528 |
| LIMA1 | LIM domain and actin binding 1 | -0.0195209 |
| PCBP2 | poly(rC) binding protein 2 | -0.0188635 |
| INSIG1 | insulin induced gene 1 | -0.0181531 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0180678 |
| JUP | junction plakoglobin | -0.0177947 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0175277 |
| TMC5 | transmembrane channel-like 5 | -0.0171672 |
| DSTN | destrin (actin depolymerizing factor) | -0.016985 |
| RPS5 | ribosomal protein S5 | -0.0168589 |
| PRSS3 | protease, serine, 3 | -0.0165652 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0165646 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0158991 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0158465 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0157534 |
| ACTN4 | actinin, alpha 4 | -0.0153499 |
| LIPH | lipase, member H | -0.0152975 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0151192 |
| HMGA1 | high mobility group AT-hook 1 | -0.0148532 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0147632 |
| MX2 | MX dynamin-like GTPase 2 | -0.0147573 |
| MUC1 | mucin 1, cell surface associated | -0.0146661 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0146556 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0142246 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0141722 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0139619 |
| RPS24 | ribosomal protein S24 | -0.0136171 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0132342 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0131532 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0130211 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0127238 |
| LOC112694756 | uncharaterized LOC112694756 | -0.012656 |
| SP100 | SP100 nuclear antigen | -0.0126098 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0124057 |
| CLDN7 | claudin 7 | -0.0122678 |
| MUC17 | mucin 17, cell surface associated | -0.0122126 |
| TPX2 | TPX2, microtubule-associated | -0.0121793 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0121715 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0120496 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0120415 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0119575 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0118345 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0117462 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0116197 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0115998 |
| RPS4X | ribosomal protein S4, X-linked | -0.0114332 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0113177 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0112379 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0111846 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0111654 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0111586 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0109159 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0108439 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0108197 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0107825 |
| TPI1 | triosephosphate isomerase 1 | -0.0105563 |
| TXNRD1 | thioredoxin reductase 1 | -0.0105532 |
| ITM2B | integral membrane protein 2B | -0.0104721 |
| RPL19 | ribosomal protein L19 | -0.0104585 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0104245 |
| STK24 | serine/threonine kinase 24 | -0.0104231 |
| SERINC3 | serine incorporator 3 | -0.0103594 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0103307 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0102974 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0100877 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0100728 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00995858 |
| AGR3 | anterior gradient 3 | -0.00989679 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00980153 |
| LCN2 | lipocalin 2 | -0.0097639 |
| LPIN1 | lipin 1 | -0.0097064 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.00969541 |
