| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.182935 |
| AHNAK | AHNAK nucleoprotein | 0.121933 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0968007 |
| FN1 | fibronectin 1 | 0.0851834 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0734977 |
| CD109 | CD109 molecule | 0.0705229 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0683114 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0646706 |
| ANXA2 | annexin A2 | 0.0637166 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0603929 |
| LSAMP | limbic system-associated membrane protein | 0.0577151 |
| CD44 | CD44 molecule (Indian blood group) | 0.0546629 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0486145 |
| CTSB | cathepsin B | 0.0485575 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0469332 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0465078 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0446486 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0435747 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.042237 |
| PTK2 | protein tyrosine kinase 2 | 0.0410321 |
| HMGA2 | high mobility group AT-hook 2 | 0.0407474 |
| PTCHD4 | patched domain containing 4 | 0.0399621 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0390475 |
| RUNX1 | runt-related transcription factor 1 | 0.0384869 |
| NAV1 | neuron navigator 1 | 0.0384758 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0381206 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0380911 |
| ATP13A3 | ATPase type 13A3 | 0.0361866 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0338316 |
| SPAG9 | sperm associated antigen 9 | 0.0324351 |
| FLNA | filamin A, alpha | 0.0321415 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0321392 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0315409 |
| ZNF292 | zinc finger protein 292 | 0.0314073 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0313218 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0307185 |
| NDRG1 | N-myc downstream regulated 1 | 0.0304037 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0293156 |
| NTM | neurotrimin | 0.0290799 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0287353 |
| H1-0 | H1.0 linker histone | 0.0280174 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0277244 |
| INHBA | inhibin, beta A | 0.0274037 |
| CANX | calnexin | 0.0271316 |
| NUP58 | nucleoporin 58 | 0.026885 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0262129 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.026083 |
| KLF6 | Kruppel-like factor 6 | 0.0260607 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0259686 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0259362 |
| MYO10 | myosin X | 0.0255832 |
| HELZ | helicase with zinc finger | 0.0255542 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0255407 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0253853 |
| USP3 | ubiquitin specific peptidase 3 | 0.0250276 |
| CORO1C | coronin, actin binding protein, 1C | 0.0245903 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0244178 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0235067 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0234929 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0234523 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0233284 |
| RNF213 | ring finger protein 213 | 0.0230662 |
| FLNC | filamin C, gamma | 0.0227076 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0225355 |
| UBC | ubiquitin C | 0.0225116 |
| MCL1 | myeloid cell leukemia 1 | 0.0222404 |
| RPL35A | ribosomal protein L35a | 0.0221971 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0221338 |
| GPC6 | glypican 6 | 0.0220963 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0220492 |
| RPLP0 | ribosomal protein, large, P0 | 0.0220152 |
| SMAD3 | SMAD family member 3 | 0.0219918 |
| DST | dystonin | 0.0219855 |
| ZNF217 | zinc finger protein 217 | 0.0214086 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0213362 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0205238 |
| MXI1 | MAX interactor 1, dimerization protein | 0.020362 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0202087 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.02017 |
| ENO1 | enolase 1, (alpha) | 0.0201284 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0201161 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0195751 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0193089 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0192631 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0191523 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0190268 |
| QKI | QKI, KH domain containing, RNA binding | 0.0189246 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0187527 |
| SBF2 | SET binding factor 2 | 0.018552 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0184806 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0182814 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0182751 |
| JUN | jun proto-oncogene | 0.0181228 |
| LOC112694756 | uncharaterized LOC112694756 | 0.018003 |
| VEGFA | vascular endothelial growth factor A | 0.0179817 |
| TEX14 | testis expressed 14 | 0.0177825 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0175605 |
| PLEC | plectin | 0.0173198 |
| EGR1 | early growth response 1 | 0.0172703 |
| CLIC1 | chloride intracellular channel 1 | 0.0172507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.051775 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0498199 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0489316 |
| RPS6 | ribosomal protein S6 | -0.0486956 |
| RPS2 | ribosomal protein S2 | -0.0434749 |
| USP34 | ubiquitin specific peptidase 34 | -0.0413352 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0372017 |
| CALD1 | caldesmon 1 | -0.0370938 |
| ASPH | aspartate beta-hydroxylase | -0.034016 |
| LDHA | lactate dehydrogenase A | -0.0335699 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0329913 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0327742 |
| VIM | vimentin | -0.0325876 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0321088 |
| LIMA1 | LIM domain and actin binding 1 | -0.0301058 |
| BRD2 | bromodomain containing 2 | -0.0292695 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0274377 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.026584 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0262616 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0261316 |
| RPL7 | ribosomal protein L7 | -0.0249635 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0246768 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0241232 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0241229 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0240138 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0237012 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0234235 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0232017 |
| PRRC2C | proline-rich coiled-coil 2C | -0.023191 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0228805 |
| TLE4 | transducin-like enhancer of split 4 | -0.0227162 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0221475 |
| RPL32 | ribosomal protein L32 | -0.0210076 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0204464 |
| HMGA1 | high mobility group AT-hook 1 | -0.0203332 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0202054 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0198671 |
| ZNF638 | zinc finger protein 638 | -0.0197478 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0196761 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0192571 |
| MSN | moesin | -0.019237 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0189315 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0184675 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0183245 |
| RPL21 | ribosomal protein L21 | -0.0181415 |
| RPS23 | ribosomal protein S23 | -0.0179887 |
| SEPTIN10 | septin 10 | -0.0179697 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0178818 |
| WWC2 | WW and C2 domain containing 2 | -0.0178323 |
| RPLP1 | ribosomal protein, large, P1 | -0.0175976 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0175159 |
| JMJD1C | jumonji domain containing 1C | -0.0173856 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0168933 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0168413 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0162213 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0160464 |
| RPL26 | ribosomal protein L26 | -0.016027 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0159733 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0156775 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0156663 |
| ANO6 | anoctamin 6 | -0.0156589 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0155041 |
| RPL36A | ribosomal protein L36a | -0.0154836 |
| ACTG1 | actin gamma 1 | -0.0154382 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0151873 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0150114 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0149261 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0147932 |
| TXNRD1 | thioredoxin reductase 1 | -0.0147476 |
| RND3 | Rho family GTPase 3 | -0.0146417 |
| TMF1 | TATA element modulatory factor 1 | -0.0145797 |
| UBXN4 | UBX domain protein 4 | -0.0144759 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0144273 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0143647 |
| PAX3 | paired box 3 | -0.0142407 |
| EEA1 | early endosome antigen 1 | -0.0140254 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0140124 |
| CD163L1 | CD163 molecule-like 1 | -0.0139294 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.013822 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0138201 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0138069 |
| CAVIN1 | caveolae associated protein 1 | -0.0137912 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.01376 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0136851 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0136772 |
| CCDC91 | coiled-coil domain containing 91 | -0.0136704 |
| PHF14 | PHD finger protein 14 | -0.0135717 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0134675 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.013453 |
| RBM25 | RNA binding motif protein 25 | -0.0133848 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.013377 |
| ANTXR2 | anthrax toxin receptor 2 | -0.013361 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0132861 |
| GAN | gigaxonin | -0.0132771 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0131564 |
| MT2A | metallothionein 2A | -0.0130335 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0130103 |
| SMAP1 | small ArfGAP 1 | -0.0129816 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0129501 |
| GOLGA4 | golgin A4 | -0.012853 |
