| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0973205 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0882031 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0729768 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0644564 |
| NDRG1 | N-myc downstream regulated 1 | 0.0592227 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0565178 |
| VEGFA | vascular endothelial growth factor A | 0.0558005 |
| TNS4 | tensin 4 | 0.05447 |
| ANXA2 | annexin A2 | 0.0462871 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0460921 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0419584 |
| FLNB | filamin B, beta | 0.0413329 |
| FAM13A | family with sequence similarity 13, member A | 0.0401285 |
| ITGA6 | integrin, alpha 6 | 0.0396236 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0393762 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0377943 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377149 |
| DSCAM | Down syndrome cell adhesion molecule | 0.036448 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.036431 |
| ZNF292 | zinc finger protein 292 | 0.0359507 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357543 |
| AHNAK | AHNAK nucleoprotein | 0.0343536 |
| TXNIP | thioredoxin interacting protein | 0.0338573 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337079 |
| DSPP | dentin sialophosphoprotein | 0.0334379 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0330085 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0312711 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0304403 |
| KRT8 | keratin 8, type II | 0.0296964 |
| ASPH | aspartate beta-hydroxylase | 0.0296597 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295039 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0292214 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287906 |
| MED13L | mediator complex subunit 13-like | 0.0276 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0272049 |
| PRELID2 | PRELI domain containing 2 | 0.0259245 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025417 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0251876 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250097 |
| ABHD2 | abhydrolase domain containing 2 | 0.0249989 |
| CALB1 | calbindin 1, 28kDa | 0.0248856 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0241971 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0241565 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0240906 |
| EREG | epiregulin | 0.02366 |
| TMSB4X | thymosin beta 4, X-linked | 0.023079 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0230363 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0227611 |
| TPM3 | tropomyosin 3 | 0.0222033 |
| RREB1 | ras responsive element binding protein 1 | 0.0221315 |
| CD46 | CD46 molecule, complement regulatory protein | 0.021873 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0214163 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0211573 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0209246 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0209145 |
| PTEN | phosphatase and tensin homolog | 0.0207818 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0207512 |
| CALR | calreticulin | 0.0206397 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0201943 |
| ENO1 | enolase 1, (alpha) | 0.0201328 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0200892 |
| AREG | amphiregulin | 0.0200343 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0196458 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0194495 |
| GOLGA4 | golgin A4 | 0.0193301 |
| EHF | ets homologous factor | 0.0192745 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0192635 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0191462 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0188703 |
| ATXN1 | ataxin 1 | 0.0188646 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0187838 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0187207 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0185746 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0184915 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0182937 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.018041 |
| SBF2 | SET binding factor 2 | 0.0179544 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0176768 |
| SETD5 | SET domain containing 5 | 0.0176592 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0176399 |
| PARD3 | par-3 family cell polarity regulator | 0.017627 |
| CCNY | cyclin Y | 0.0176046 |
| RPS12 | ribosomal protein S12 | 0.0175808 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0173877 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0173189 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0172519 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0172492 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.017117 |
| GSK3B | glycogen synthase kinase 3 beta | 0.017014 |
| EPHA2 | EPH receptor A2 | 0.0169771 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0168845 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0167664 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0166634 |
| SHROOM3 | shroom family member 3 | 0.0166341 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.016582 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0165418 |
| LMO7 | LIM domain 7 | 0.0165263 |
| MYO5B | myosin VB | 0.0162479 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0161811 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0161452 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0912988 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513711 |
| PTMA | prothymosin, alpha | -0.0471786 |
| RPLP1 | ribosomal protein, large, P1 | -0.0350684 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0345716 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0318622 |
| FTL | ferritin, light polypeptide | -0.0298165 |
| RPS24 | ribosomal protein S24 | -0.0193718 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0171612 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0156938 |
| RPL32 | ribosomal protein L32 | -0.0152212 |
| GDF15 | growth differentiation factor 15 | -0.0149999 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0147899 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.014569 |
| S100A10 | S100 calcium binding protein A10 | -0.0129666 |
| AGR2 | anterior gradient 2 | -0.0127644 |
| RPL31 | ribosomal protein L31 | -0.0124213 |
| NPR2 | natriuretic peptide receptor 2 | -0.011721 |
| LDHA | lactate dehydrogenase A | -0.0111485 |
| CCND1 | cyclin D1 | -0.0108889 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0107636 |
| IER3 | immediate early response 3 | -0.0107576 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00968535 |
| RPL4 | ribosomal protein L4 | -0.0096309 |
| RPL34 | ribosomal protein L34 | -0.00956716 |
| RPS20 | ribosomal protein S20 | -0.00956051 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.00953023 |
| RPS5 | ribosomal protein S5 | -0.00945877 |
| ARF1 | ADP-ribosylation factor 1 | -0.00920762 |
| RPL27A | ribosomal protein L27a | -0.0090882 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00890923 |
| GNAS | GNAS complex locus | -0.00864959 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.00864391 |
| RPL36A | ribosomal protein L36a | -0.00856828 |
| RPL14 | ribosomal protein L14 | -0.00856093 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00848117 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.00836606 |
| RPS16 | ribosomal protein S16 | -0.00834077 |
| RPL8 | ribosomal protein L8 | -0.00808717 |
| S100A9 | S100 calcium binding protein A9 | -0.00799197 |
| POF1B | premature ovarian failure, 1B | -0.00791577 |
| RPS21 | ribosomal protein S21 | -0.00786059 |
| LMNA | lamin A/C | -0.00775749 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00773445 |
| HMGB1 | high mobility group box 1 | -0.00770875 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00770684 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00770576 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.00746407 |
| RESF1 | retroelement silencing factor 1 | -0.00737915 |
| RPL36AL | ribosomal protein L36a-like | -0.00717808 |
| RPS19 | ribosomal protein S19 | -0.00686455 |
| S100P | S100 calcium binding protein P | -0.00686266 |
| RPS25 | ribosomal protein S25 | -0.00684605 |
| NRN1 | neuritin 1 | -0.00680036 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00671427 |
| RPLP0 | ribosomal protein, large, P0 | -0.00665541 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.00664536 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.00659394 |
| KLK10 | kallikrein-related peptidase 10 | -0.00650118 |
| RRBP1 | ribosome binding protein 1 | -0.00646112 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00639108 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00635457 |
| EGR1 | early growth response 1 | -0.00628878 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00623361 |
| PARK7 | parkinson protein 7 | -0.00615445 |
| TUBB | tubulin, beta class I | -0.00609409 |
| ASTN2 | astrotactin 2 | -0.00605252 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.00595371 |
| CBX3 | chromobox homolog 3 | -0.00594225 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00588328 |
| MYO1E | myosin IE | -0.0058657 |
| RPL39 | ribosomal protein L39 | -0.00584433 |
| RPL11 | ribosomal protein L11 | -0.00573596 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00570395 |
| LYZ | lysozyme | -0.00569331 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00567692 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.00567547 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0056742 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00566542 |
| NPSR1 | neuropeptide S receptor 1 | -0.00566234 |
| RPLP2 | ribosomal protein, large, P2 | -0.00555007 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00554705 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00553132 |
| CST3 | cystatin C | -0.00548209 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.00542045 |
| S100A6 | S100 calcium binding protein A6 | -0.00539043 |
| CA9 | carbonic anhydrase IX | -0.00538868 |
| RPL37 | ribosomal protein L37 | -0.00537581 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.00534877 |
| RPS6 | ribosomal protein S6 | -0.0053379 |
| PERP | PERP, TP53 apoptosis effector | -0.00525087 |
| RPS23 | ribosomal protein S23 | -0.00522513 |
| SERF2 | small EDRK-rich factor 2 | -0.00522241 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.00521289 |
| VCL | vinculin | -0.00517945 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00516368 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.00516137 |
| ASB4 | ankyrin repeat and SOCS box containing 4 | -0.00506408 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.00500308 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00498518 |
