| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.116573 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102918 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.101121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101057 |
| TMSB4X | thymosin beta 4, X-linked | 0.0948506 |
| TXNRD1 | thioredoxin reductase 1 | 0.0948419 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0844145 |
| AHNAK | AHNAK nucleoprotein | 0.0756408 |
| RAI1 | retinoic acid induced 1 | 0.074124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0718192 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0715811 |
| VIM | vimentin | 0.069223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0630136 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0570381 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0547846 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0536659 |
| CENPF | centromere protein F, 350/400kDa | 0.0533822 |
| ACTG1 | actin gamma 1 | 0.0524635 |
| RTN4 | reticulon 4 | 0.0514943 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0504317 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0503369 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0469475 |
| SPAG9 | sperm associated antigen 9 | 0.0459488 |
| LOC112694756 | uncharaterized LOC112694756 | 0.044886 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0447466 |
| CANX | calnexin | 0.043605 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0432925 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0429146 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0421532 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0421085 |
| EREG | epiregulin | 0.0412882 |
| MT2A | metallothionein 2A | 0.0410211 |
| MKI67 | marker of proliferation Ki-67 | 0.0404482 |
| KLF6 | Kruppel-like factor 6 | 0.0382268 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0377307 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0368252 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0367307 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0361089 |
| APP | amyloid beta (A4) precursor protein | 0.0357978 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0356529 |
| TMEM41B | transmembrane protein 41B | 0.034455 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0340104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0338303 |
| SMC4 | structural maintenance of chromosomes 4 | 0.033578 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0335068 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0330452 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0330224 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0326149 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0315648 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0314551 |
| EZR | ezrin | 0.0310096 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0307158 |
| SRGN | serglycin | 0.0306669 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0306138 |
| ANLN | anillin, actin binding protein | 0.0305911 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0300872 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300768 |
| ANXA1 | annexin A1 | 0.0296865 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0296318 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0295701 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0294896 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0288792 |
| JMJD1C | jumonji domain containing 1C | 0.0287781 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0287065 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283494 |
| YBX1 | Y box binding protein 1 | 0.0278528 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0276808 |
| PGK1 | phosphoglycerate kinase 1 | 0.0275766 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0274899 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272663 |
| TOP1 | topoisomerase (DNA) I | 0.0270849 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0269254 |
| ZNF292 | zinc finger protein 292 | 0.0266396 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.026472 |
| CEP170 | centrosomal protein 170kDa | 0.0260751 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0260278 |
| SET | SET nuclear proto-oncogene | 0.0259202 |
| ARRDC3 | arrestin domain containing 3 | 0.0259087 |
| SEPTIN7 | septin 7 | 0.0257288 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0255632 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0254533 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.025403 |
| MT1X | metallothionein 1X | 0.0252664 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251735 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0251481 |
| EMP1 | epithelial membrane protein 1 | 0.0250825 |
| SRPK2 | SRSF protein kinase 2 | 0.0250472 |
| YBX3 | Y box binding protein 3 | 0.024954 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0248751 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0247911 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.024495 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0244318 |
| OGA | O-GlcNAcase | 0.0239752 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0239637 |
| PRRC2C | proline-rich coiled-coil 2C | 0.023784 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0237639 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0236103 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0234276 |
| KIF5B | kinesin family member 5B | 0.0233449 |
| USP34 | ubiquitin specific peptidase 34 | 0.0231811 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.11672 |
| HLA-B | major histocompatibility complex, class I, B | -0.0728786 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0651749 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0650333 |
| TMSB10 | thymosin beta 10 | -0.0622135 |
| CADM2 | cell adhesion molecule 2 | -0.0560158 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0458096 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0445797 |
| TNS3 | tensin 3 | -0.03751 |
| RPL35A | ribosomal protein L35a | -0.0374738 |
| RPL31 | ribosomal protein L31 | -0.0373846 |
| FTL | ferritin, light polypeptide | -0.037235 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0370902 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0367355 |
| EFNA5 | ephrin-A5 | -0.0360146 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0348859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308554 |
| RPS6 | ribosomal protein S6 | -0.0306515 |
| SP100 | SP100 nuclear antigen | -0.0302819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0280769 |
| RPL37A | ribosomal protein L37a | -0.0277547 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0271176 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.027013 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0265374 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0262645 |
| RPL36A | ribosomal protein L36a | -0.0254349 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0250963 |
| EPHA4 | EPH receptor A4 | -0.0248695 |
| RPLP1 | ribosomal protein, large, P1 | -0.0244971 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.023569 |
| RNF213 | ring finger protein 213 | -0.0229314 |
| RIGI | RNA sensor RIG-I | -0.0229237 |
| RPL37 | ribosomal protein L37 | -0.0225749 |
| RPS29 | ribosomal protein S29 | -0.0224432 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.022359 |
| RPS23 | ribosomal protein S23 | -0.0223362 |
| DPYD | dihydropyrimidine dehydrogenase | -0.021422 |
| RPS19 | ribosomal protein S19 | -0.0213154 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0211062 |
| RPS24 | ribosomal protein S24 | -0.0208855 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0204838 |
| RPL36 | ribosomal protein L36 | -0.0203685 |
| RPS10 | ribosomal protein S10 | -0.0202663 |
| DNER | delta/notch-like EGF repeat containing | -0.019999 |
| B2M | beta-2-microglobulin | -0.0196985 |
| PRELID2 | PRELI domain containing 2 | -0.0196362 |
| EGR1 | early growth response 1 | -0.0194297 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0192098 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0185658 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.018493 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0184095 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0184046 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0183784 |
| RPS25 | ribosomal protein S25 | -0.018102 |
| DST | dystonin | -0.0179813 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179298 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.017796 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0176091 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0174708 |
| INTS6 | integrator complex subunit 6 | -0.0171115 |
| DPH6 | diphthamine biosynthesis 6 | -0.0170573 |
| RPS12 | ribosomal protein S12 | -0.0166651 |
| HMGA1 | high mobility group AT-hook 1 | -0.0165972 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0164733 |
| RPLP2 | ribosomal protein, large, P2 | -0.0163722 |
| HLA-A | major histocompatibility complex, class I, A | -0.0163015 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0159231 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0152308 |
| RPS27 | ribosomal protein S27 | -0.0148802 |
| TGM2 | transglutaminase 2 | -0.0148204 |
| RPS17 | ribosomal protein S17 | -0.0140514 |
| PLSCR1 | phospholipid scramblase 1 | -0.0135555 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0133533 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0130402 |
| RPL34 | ribosomal protein L34 | -0.0130325 |
| TRIM56 | tripartite motif containing 56 | -0.0130072 |
| RPS13 | ribosomal protein S13 | -0.0128973 |
| RPL38 | ribosomal protein L38 | -0.0128236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0127953 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0125671 |
| PMP22 | peripheral myelin protein 22 | -0.0125445 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0124994 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0123811 |
| COL5A2 | collagen, type V, alpha 2 | -0.0122731 |
| TPRG1 | tumor protein p63 regulated 1 | -0.012119 |
| ANKRD26 | ankyrin repeat domain 26 | -0.0119635 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0117991 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0116169 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.011566 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0114318 |
| EHBP1 | EH domain binding protein 1 | -0.0113638 |
| AEBP2 | AE binding protein 2 | -0.0113457 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0112097 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0111731 |
| PLIN2 | perilipin 2 | -0.0111664 |
| TRIM5 | tripartite motif containing 5 | -0.0109534 |
| RAD51B | RAD51 paralog B | -0.010921 |
| RPS3 | ribosomal protein S3 | -0.0108078 |
| MEF2A | myocyte enhancer factor 2A | -0.0108046 |
| SMAD9 | SMAD family member 9 | -0.0107251 |
