| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.156042 |
| FN1 | fibronectin 1 | 0.118931 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.100571 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0887111 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0736548 |
| FAM13A | family with sequence similarity 13, member A | 0.0688391 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.068709 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0660043 |
| TMSB10 | thymosin beta 10 | 0.0557118 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0554141 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0528 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0524695 |
| MAP1B | microtubule-associated protein 1B | 0.0501778 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0494216 |
| NDRG1 | N-myc downstream regulated 1 | 0.0493208 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0487375 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0483468 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0475857 |
| GOLGA4 | golgin A4 | 0.0466673 |
| ANXA2 | annexin A2 | 0.04542 |
| S100A6 | S100 calcium binding protein A6 | 0.0435903 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0423042 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0414391 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0388388 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0381756 |
| RIOK3 | RIO kinase 3 | 0.0380777 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0378135 |
| ATP13A3 | ATPase type 13A3 | 0.0375319 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0363838 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0362624 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0359348 |
| VEGFA | vascular endothelial growth factor A | 0.0357742 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0355057 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0348737 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0347435 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0346939 |
| MEF2A | myocyte enhancer factor 2A | 0.0334974 |
| EGR1 | early growth response 1 | 0.033275 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0331063 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0330702 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0323806 |
| VIM | vimentin | 0.032176 |
| TMSB4X | thymosin beta 4, X-linked | 0.0321126 |
| USP3 | ubiquitin specific peptidase 3 | 0.0308737 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0305102 |
| SNX9 | sorting nexin 9 | 0.0304563 |
| SETD5 | SET domain containing 5 | 0.0302245 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0295867 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0294796 |
| FTL | ferritin, light polypeptide | 0.0293894 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.029353 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0292343 |
| SIK3 | SIK family kinase 3 | 0.0287008 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0284963 |
| CD44 | CD44 molecule (Indian blood group) | 0.0282572 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.027298 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.027057 |
| SYAP1 | synapse associated protein 1 | 0.0269569 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0267291 |
| RBM39 | RNA binding motif protein 39 | 0.0262217 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0255456 |
| RUNX2 | runt-related transcription factor 2 | 0.0255048 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0254545 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253513 |
| OSMR | oncostatin M receptor | 0.0249471 |
| ZNF292 | zinc finger protein 292 | 0.0249276 |
| HELZ | helicase with zinc finger | 0.0246681 |
| HMGA2 | high mobility group AT-hook 2 | 0.0246662 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0246047 |
| STC1 | stanniocalcin 1 | 0.0243051 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.024273 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240173 |
| PRSS23 | protease, serine, 23 | 0.023941 |
| CD109 | CD109 molecule | 0.0236905 |
| SBF2 | SET binding factor 2 | 0.0235596 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0234781 |
| H1-0 | H1.0 linker histone | 0.023131 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0223422 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0222419 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0222278 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0221401 |
| ADM | adrenomedullin | 0.0221272 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0219932 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0219251 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0218286 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0212233 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.021208 |
| GPC6 | glypican 6 | 0.0209067 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0208287 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0206031 |
| HMGA1 | high mobility group AT-hook 1 | 0.0205807 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0204894 |
| CLMP | CXADR-like membrane protein | 0.0203978 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0203708 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0203311 |
| JMJD1C | jumonji domain containing 1C | 0.0202278 |
| TMEM87A | transmembrane protein 87A | 0.0202052 |
| NRP1 | neuropilin 1 | 0.0201809 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0200703 |
| RTN4 | reticulon 4 | 0.0200206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | -0.0726669 |
| FAM20C | family with sequence similarity 20, member C | -0.0714814 |
| PCBP2 | poly(rC) binding protein 2 | -0.0581468 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.058035 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0528236 |
| NRG1 | neuregulin 1 | -0.0518783 |
| UBC | ubiquitin C | -0.051061 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0508107 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0440295 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0433121 |
| CDH13 | cadherin 13 | -0.0390036 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0375577 |
| MTSS1 | metastasis suppressor 1 | -0.0358167 |
| INTS6 | integrator complex subunit 6 | -0.0351276 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0317474 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0287537 |
| HDLBP | high density lipoprotein binding protein | -0.0284664 |
| EFNA5 | ephrin-A5 | -0.0281333 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0279501 |
| EGFR | epidermal growth factor receptor | -0.0278743 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0278173 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0271792 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0263024 |
| AADAC | arylacetamide deacetylase | -0.025098 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0246816 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244655 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0244106 |
| RPL23 | ribosomal protein L23 | -0.0243572 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0241937 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.02411 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.02392 |
| FRMD4A | FERM domain containing 4A | -0.0219603 |
| ZNF638 | zinc finger protein 638 | -0.0214654 |
| FBN1 | fibrillin 1 | -0.0206387 |
| NLK | nemo-like kinase | -0.0205267 |
| IFI44L | interferon-induced protein 44-like | -0.0204292 |
| KYNU | kynureninase | -0.020342 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0200129 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0199411 |
| HEATR5A | HEAT repeat containing 5A | -0.0192025 |
| LDHA | lactate dehydrogenase A | -0.0186008 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0185464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0178767 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0177085 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0175612 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0174685 |
| NAV2 | neuron navigator 2 | -0.0167896 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0167445 |
| CTBP2 | C-terminal binding protein 2 | -0.0165572 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0164802 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0163802 |
| IFI44 | interferon-induced protein 44 | -0.0163545 |
| ASPH | aspartate beta-hydroxylase | -0.0163452 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0162703 |
| CPNE1 | copine I | -0.0162674 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0162293 |
| AEBP2 | AE binding protein 2 | -0.0161695 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0161377 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.015846 |
| ZNF804A | zinc finger protein 804A | -0.0156273 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0156128 |
| RPS27A | ribosomal protein S27a | -0.0155397 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0155374 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0155087 |
| R3HDM2 | R3H domain containing 2 | -0.0153974 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0153564 |
| ATG7 | autophagy related 7 | -0.0152819 |
| PKM | pyruvate kinase, muscle | -0.0150462 |
| HDAC4 | histone deacetylase 4 | -0.014695 |
| ATM | ATM serine/threonine kinase | -0.0145244 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0144591 |
| PHF3 | PHD finger protein 3 | -0.0144072 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0143085 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0141373 |
| NABP1 | nucleic acid binding protein 1 | -0.0140576 |
| ATF7 | activating transcription factor 7 | -0.0140067 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0139099 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0138967 |
| AVIL | advillin | -0.0138855 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0137926 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0137882 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0137696 |
| SMAD3 | SMAD family member 3 | -0.0137674 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0137049 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0136793 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0136727 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0131243 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 | -0.0131227 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.012924 |
| RPL4 | ribosomal protein L4 | -0.0129032 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0127841 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0126273 |
| TPM1 | tropomyosin 1 (alpha) | -0.0126014 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0125744 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0123855 |
| AUTS2 | autism susceptibility candidate 2 | -0.0123855 |
| APP | amyloid beta (A4) precursor protein | -0.0122706 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0122182 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0121297 |
| FANK1 | fibronectin type III and ankyrin repeat domains 1 | -0.0120492 |
