| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0613095 |
| TMSB4X | thymosin beta 4, X-linked | 0.0512662 |
| ZNF292 | zinc finger protein 292 | 0.0457902 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0424428 |
| DST | dystonin | 0.0416342 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0407834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0302269 |
| H1-0 | H1.0 linker histone | 0.0289956 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0282627 |
| CCN2 | cellular communication network factor 2 | 0.0279263 |
| SPAG9 | sperm associated antigen 9 | 0.026377 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0257053 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0247077 |
| PDGFC | platelet derived growth factor C | 0.0245249 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0239361 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0232544 |
| COL5A2 | collagen, type V, alpha 2 | 0.0232522 |
| AHNAK | AHNAK nucleoprotein | 0.0215893 |
| MYO10 | myosin X | 0.0207465 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0203985 |
| WDR43 | WD repeat domain 43 | 0.0203891 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0203045 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0202077 |
| MED13L | mediator complex subunit 13-like | 0.0200093 |
| TPM3 | tropomyosin 3 | 0.0198651 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0196055 |
| NCKAP1 | NCK-associated protein 1 | 0.0189856 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0189839 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0187164 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0185234 |
| ITGAV | integrin, alpha V | 0.0184934 |
| ZNF217 | zinc finger protein 217 | 0.0184121 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183317 |
| SRP54 | signal recognition particle 54kDa | 0.0181898 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0180963 |
| YBX1 | Y box binding protein 1 | 0.0180955 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0180811 |
| CANX | calnexin | 0.0180697 |
| FNDC3B | fibronectin type III domain containing 3B | 0.017927 |
| PEG10 | paternally expressed 10 | 0.0179036 |
| CDC73 | cell division cycle 73 | 0.0177844 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0176031 |
| QKI | QKI, KH domain containing, RNA binding | 0.0174906 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.017119 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0169629 |
| MB21D2 | Mab-21 domain containing 2 | 0.0168103 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0166504 |
| TPX2 | TPX2, microtubule-associated | 0.0163747 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0163437 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0162189 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0162169 |
| XPO1 | exportin 1 | 0.0161803 |
| ANXA1 | annexin A1 | 0.0161694 |
| MKI67 | marker of proliferation Ki-67 | 0.0161466 |
| ZNF451 | zinc finger protein 451 | 0.015736 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0154981 |
| MTF2 | metal response element binding transcription factor 2 | 0.0154972 |
| CALU | calumenin | 0.0154359 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0151852 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0149683 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0149471 |
| ENO1 | enolase 1, (alpha) | 0.014733 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0146589 |
| ANXA5 | annexin A5 | 0.0146513 |
| RAI1 | retinoic acid induced 1 | 0.0145214 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0144237 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0143241 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0136314 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0134176 |
| YAP1 | Yes-associated protein 1 | 0.0131561 |
| RPS2 | ribosomal protein S2 | 0.0131167 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0131095 |
| ANXA2 | annexin A2 | 0.0130725 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0130359 |
| PFN1 | profilin 1 | 0.0129745 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0129616 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0128447 |
| HMGB2 | high mobility group box 2 | 0.0126138 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0124969 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0124437 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0123691 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0123618 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0122349 |
| ZFR | zinc finger RNA binding protein | 0.0122099 |
| USP3 | ubiquitin specific peptidase 3 | 0.0121461 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0120861 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0120587 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0119722 |
| INTS13 | integrator complex subunit 13 | 0.0119352 |
| ZNF608 | zinc finger protein 608 | 0.0119212 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0119147 |
| FOXG1 | forkhead box G1 | 0.0118428 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0118154 |
| RIOK3 | RIO kinase 3 | 0.0118102 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0117956 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.011736 |
| ATG5 | autophagy related 5 | 0.0116742 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0116182 |
| NPTN | neuroplastin | 0.0115106 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0113195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0744488 |
| VIM | vimentin | -0.0551876 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0538724 |
| RPLP1 | ribosomal protein, large, P1 | -0.0365265 |
| PTMA | prothymosin, alpha | -0.0295489 |
| FTL | ferritin, light polypeptide | -0.029538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.028418 |
| RPL31 | ribosomal protein L31 | -0.0277518 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0264621 |
| RPS16 | ribosomal protein S16 | -0.0252951 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0246873 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0238746 |
| CDH19 | cadherin 19, type 2 | -0.0237848 |
| RPS8 | ribosomal protein S8 | -0.0230971 |
| FOXP2 | forkhead box P2 | -0.0230889 |
| RPS24 | ribosomal protein S24 | -0.0214305 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.019698 |
| APOE | apolipoprotein E | -0.0192461 |
| PCDH9 | protocadherin 9 | -0.0187026 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0183772 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0182857 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0159379 |
| GNAS | GNAS complex locus | -0.0158634 |
| SNX6 | sorting nexin 6 | -0.0156819 |
| WASF2 | WAS protein family, member 2 | -0.015676 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0155605 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0155437 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0154347 |
| RBM25 | RNA binding motif protein 25 | -0.0152021 |
| RFPL4B | ret finger protein-like 4B | -0.0146736 |
| RPL36A | ribosomal protein L36a | -0.0146328 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0145468 |
| RPS27 | ribosomal protein S27 | -0.0144269 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0143177 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0140243 |
| PARK7 | parkinson protein 7 | -0.0136066 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0135648 |
| RLF | rearranged L-myc fusion | -0.0130945 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0129172 |
| RPS19 | ribosomal protein S19 | -0.0128963 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0128745 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0127897 |
| RPL9 | ribosomal protein L9 | -0.0126051 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0125865 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0123979 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0123644 |
| SERF2 | small EDRK-rich factor 2 | -0.0123569 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0123526 |
| PHIP | pleckstrin homology domain interacting protein | -0.0117095 |
| TENM3 | teneurin transmembrane protein 3 | -0.0116066 |
| RPL37 | ribosomal protein L37 | -0.0114 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0113291 |
| RPL19 | ribosomal protein L19 | -0.0113257 |
| PLPP1 | phospholipid phosphatase 1 | -0.0113149 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0112947 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0112264 |
| INTS6 | integrator complex subunit 6 | -0.0111442 |
| RPL30 | ribosomal protein L30 | -0.0111381 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.011107 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0110114 |
| FST | follistatin | -0.0108901 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0108836 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.0108815 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0108505 |
| CCDC138 | coiled-coil domain containing 138 | -0.0107647 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0107553 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0107184 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0107061 |
| RPL27A | ribosomal protein L27a | -0.0106753 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0105657 |
| TJP1 | tight junction protein 1 | -0.0105196 |
| RPL11 | ribosomal protein L11 | -0.0104997 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0104925 |
| RPS23 | ribosomal protein S23 | -0.0103444 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0102834 |
| NXN | nucleoredoxin | -0.0102315 |
| RPL35A | ribosomal protein L35a | -0.0101512 |
| LRRC4C | leucine rich repeat containing 4C | -0.0101084 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00999903 |
| GPATCH8 | G patch domain containing 8 | -0.00995515 |
| RPS25 | ribosomal protein S25 | -0.00994539 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0099404 |
| RPS17 | ribosomal protein S17 | -0.00993625 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00988929 |
| SKIL | SKI-like proto-oncogene | -0.00986713 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.00981767 |
| ASTN2 | astrotactin 2 | -0.00965945 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00965084 |
| PDCD10 | programmed cell death 10 | -0.00955315 |
| TNRC6B | trinucleotide repeat containing 6B | -0.00950861 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.00948271 |
| PCNX4 | pecanex 4 | -0.00945516 |
| SIK2 | salt-inducible kinase 2 | -0.00939221 |
| RAD51B | RAD51 paralog B | -0.00932378 |
| NCOR1 | nuclear receptor corepressor 1 | -0.00926159 |
| LDHA | lactate dehydrogenase A | -0.00923431 |
| FOXC1 | forkhead box C1 | -0.00912146 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.00909622 |
| EAPP | E2F-associated phosphoprotein | -0.00898075 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.00895967 |
