| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0763946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0674778 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0486109 |
| SMAD3 | SMAD family member 3 | 0.0462265 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0462103 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0460158 |
| CD44 | CD44 molecule (Indian blood group) | 0.0431076 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0422969 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0386132 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0354455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.033652 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.032302 |
| SBF2 | SET binding factor 2 | 0.0319948 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0308199 |
| SEPTIN9 | septin 9 | 0.0300001 |
| PDE10A | phosphodiesterase 10A | 0.0297343 |
| ATP13A3 | ATPase type 13A3 | 0.029056 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0287094 |
| SPAG9 | sperm associated antigen 9 | 0.028609 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0281413 |
| ANXA2 | annexin A2 | 0.0270196 |
| ARRDC3 | arrestin domain containing 3 | 0.0269359 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0260548 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.025543 |
| ZNF292 | zinc finger protein 292 | 0.025524 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0247535 |
| RTN4 | reticulon 4 | 0.0238519 |
| CDK19 | cyclin-dependent kinase 19 | 0.022555 |
| AHNAK | AHNAK nucleoprotein | 0.0225495 |
| ANLN | anillin, actin binding protein | 0.0222488 |
| ZFP36 | ZFP36 ring finger protein | 0.0219741 |
| JMJD1C | jumonji domain containing 1C | 0.0217504 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0211775 |
| TPM3 | tropomyosin 3 | 0.0206457 |
| OGA | O-GlcNAcase | 0.020033 |
| FMNL2 | formin-like 2 | 0.0196557 |
| YBX1 | Y box binding protein 1 | 0.0195853 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0188794 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0187994 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0184386 |
| AFDN | afadin, adherens junction formation factor | 0.0182162 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0176407 |
| NAV2 | neuron navigator 2 | 0.0175963 |
| WDR43 | WD repeat domain 43 | 0.0172181 |
| FOSL1 | FOS-like antigen 1 | 0.016623 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0166094 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0165452 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0164329 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0160661 |
| APP | amyloid beta (A4) precursor protein | 0.0159945 |
| DST | dystonin | 0.0157672 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0156618 |
| VEGFA | vascular endothelial growth factor A | 0.0155393 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0154037 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0153502 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0151267 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0150355 |
| GOLT1A | golgi transport 1A | 0.0150058 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0148793 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0148196 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0147859 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0147581 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0145995 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0145719 |
| NUP58 | nucleoporin 58 | 0.0143949 |
| HPCAL1 | hippocalcin-like 1 | 0.0142527 |
| MED13L | mediator complex subunit 13-like | 0.0139684 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0139587 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0138275 |
| GOLGA4 | golgin A4 | 0.0136051 |
| SUCO | SUN domain containing ossification factor | 0.0136018 |
| FOXJ3 | forkhead box J3 | 0.0135607 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0131209 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.013053 |
| YAP1 | Yes-associated protein 1 | 0.01302 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0129515 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0128701 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0128023 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.012594 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0125681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0125126 |
| RUNX1 | runt-related transcription factor 1 | 0.0124105 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0123147 |
| CD109 | CD109 molecule | 0.0120273 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0120015 |
| PCBP2 | poly(rC) binding protein 2 | 0.0119899 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0119834 |
| NUP153 | nucleoporin 153kDa | 0.0119604 |
| DENND5A | DENN/MADD domain containing 5A | 0.0119497 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0119233 |
| XPO1 | exportin 1 | 0.0119089 |
| FAT1 | FAT atypical cadherin 1 | 0.0118261 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0117904 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0117278 |
| CCNL1 | cyclin L1 | 0.0117226 |
| SNX14 | sorting nexin 14 | 0.0117206 |
| RPN1 | ribophorin I | 0.0116899 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0116785 |
| TPD52 | tumor protein D52 | 0.011534 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0114679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.143719 |
| RPS16 | ribosomal protein S16 | -0.130178 |
| TMSB10 | thymosin beta 10 | -0.0935746 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0789952 |
| VCL | vinculin | -0.0680282 |
| RPLP1 | ribosomal protein, large, P1 | -0.0640782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.051668 |
| FTL | ferritin, light polypeptide | -0.0497602 |
| RPS24 | ribosomal protein S24 | -0.04353 |
| PTMA | prothymosin, alpha | -0.0331073 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0298668 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0286597 |
| EGR1 | early growth response 1 | -0.0285928 |
| RPLP2 | ribosomal protein, large, P2 | -0.0278921 |
| MT2A | metallothionein 2A | -0.0224107 |
| RPL31 | ribosomal protein L31 | -0.0224019 |
| RPS5 | ribosomal protein S5 | -0.0216357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0213718 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0213403 |
| RPL36A | ribosomal protein L36a | -0.020959 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0206256 |
| RPL35A | ribosomal protein L35a | -0.0206105 |
| MED29 | mediator complex subunit 29 | -0.0194096 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0189094 |
| RPS19 | ribosomal protein S19 | -0.0184369 |
| CTSD | cathepsin D | -0.0183747 |
| RPLP0 | ribosomal protein, large, P0 | -0.0171718 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0164006 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0163195 |
| RPS25 | ribosomal protein S25 | -0.015959 |
| LDHA | lactate dehydrogenase A | -0.01571 |
| RPL27A | ribosomal protein L27a | -0.0152985 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0150654 |
| RPL32 | ribosomal protein L32 | -0.0148552 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.014853 |
| IER3 | immediate early response 3 | -0.0145918 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0145384 |
| RPS23 | ribosomal protein S23 | -0.0143031 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0139942 |
| FBL | fibrillarin | -0.0139236 |
| RPL34 | ribosomal protein L34 | -0.0137712 |
| RPL12 | ribosomal protein L12 | -0.0137086 |
| RPS20 | ribosomal protein S20 | -0.0136568 |
| RPS13 | ribosomal protein S13 | -0.0136352 |
| LMNA | lamin A/C | -0.0131819 |
| PKM | pyruvate kinase, muscle | -0.0130548 |
| PARK7 | parkinson protein 7 | -0.0129373 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0128903 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0122592 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0118414 |
| RPS21 | ribosomal protein S21 | -0.0115661 |
| RPL11 | ribosomal protein L11 | -0.0115017 |
| MYO1E | myosin IE | -0.0113729 |
| RPL38 | ribosomal protein L38 | -0.0110946 |
| RPL4 | ribosomal protein L4 | -0.0109788 |
| RPS17 | ribosomal protein S17 | -0.0109636 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0108792 |
| RPS29 | ribosomal protein S29 | -0.010821 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0107955 |
| HMGA1 | high mobility group AT-hook 1 | -0.0106522 |
| ASPH | aspartate beta-hydroxylase | -0.0104836 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0103887 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0102953 |
| RPS14 | ribosomal protein S14 | -0.0102253 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00979965 |
| S100A10 | S100 calcium binding protein A10 | -0.00968068 |
| GOLGB1 | golgin B1 | -0.00946715 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00943549 |
| RPS4X | ribosomal protein S4, X-linked | -0.009125 |
| RPS6 | ribosomal protein S6 | -0.00909571 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00899606 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00890738 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00889857 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00889464 |
| HDLBP | high density lipoprotein binding protein | -0.00888934 |
| SERF2 | small EDRK-rich factor 2 | -0.0088347 |
| RPL37 | ribosomal protein L37 | -0.00882292 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00881879 |
| HMGA2 | high mobility group AT-hook 2 | -0.00875992 |
| INTS6 | integrator complex subunit 6 | -0.00872484 |
| RPS15 | ribosomal protein S15 | -0.00848828 |
| RPL9 | ribosomal protein L9 | -0.00835796 |
| RPS10 | ribosomal protein S10 | -0.00834344 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00826066 |
| ASTN2 | astrotactin 2 | -0.00822036 |
| RRBP1 | ribosome binding protein 1 | -0.00821807 |
| NCOA7 | nuclear receptor coactivator 7 | -0.00819223 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0081263 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00810851 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.00805968 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00805022 |
| TPM1 | tropomyosin 1 (alpha) | -0.00798293 |
| RPL8 | ribosomal protein L8 | -0.00798086 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00796365 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.00795898 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0079293 |
| CAVIN1 | caveolae associated protein 1 | -0.00792267 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00782899 |
| DLL3 | delta-like 3 (Drosophila) | -0.00765854 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.0076136 |
