| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0995155 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0802914 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0680807 |
| FAM3C | family with sequence similarity 3, member C | 0.0604162 |
| MYO6 | myosin VI | 0.0510009 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0501285 |
| OGA | O-GlcNAcase | 0.0485657 |
| AHNAK | AHNAK nucleoprotein | 0.0478663 |
| KRT17 | keratin 17, type I | 0.0437199 |
| ANXA2 | annexin A2 | 0.0434929 |
| ARRDC3 | arrestin domain containing 3 | 0.041511 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0413893 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0386459 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0386333 |
| ANLN | anillin, actin binding protein | 0.0382193 |
| CALR | calreticulin | 0.0371555 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0369217 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0364361 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.036341 |
| SPAG9 | sperm associated antigen 9 | 0.0355641 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0348608 |
| GOLGA4 | golgin A4 | 0.0346493 |
| RUNX1 | runt-related transcription factor 1 | 0.0345901 |
| NAV2 | neuron navigator 2 | 0.0345359 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0340019 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0324877 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.032134 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0318372 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312376 |
| RTN4 | reticulon 4 | 0.0307437 |
| ECT2 | epithelial cell transforming 2 | 0.0305458 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0303951 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0295483 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0286453 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.02863 |
| XPO1 | exportin 1 | 0.0282202 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0273646 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0273375 |
| CCNL1 | cyclin L1 | 0.0270461 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.026646 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0264587 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026326 |
| AFDN | afadin, adherens junction formation factor | 0.0262817 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0261127 |
| NDRG1 | N-myc downstream regulated 1 | 0.0258251 |
| FOSL1 | FOS-like antigen 1 | 0.0253811 |
| RLF | rearranged L-myc fusion | 0.0253282 |
| ZNF292 | zinc finger protein 292 | 0.0252732 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0251206 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0250208 |
| ATP13A3 | ATPase type 13A3 | 0.0248847 |
| TGM2 | transglutaminase 2 | 0.0247143 |
| TFG | TRK-fused gene | 0.0246935 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0245442 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0245153 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0241128 |
| ATP11B | ATPase, class VI, type 11B | 0.024034 |
| RASA2 | RAS p21 protein activator 2 | 0.0240019 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.023903 |
| USP3 | ubiquitin specific peptidase 3 | 0.0238937 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.023873 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0237532 |
| HLA-C | major histocompatibility complex, class I, C | 0.0236052 |
| RIOK3 | RIO kinase 3 | 0.0231084 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0230691 |
| RBM39 | RNA binding motif protein 39 | 0.0228258 |
| SLTM | SAFB-like, transcription modulator | 0.0224045 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0224042 |
| DSPP | dentin sialophosphoprotein | 0.0218663 |
| JMJD1C | jumonji domain containing 1C | 0.0218439 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.021727 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0215928 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0215799 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0215184 |
| VEGFA | vascular endothelial growth factor A | 0.0215086 |
| NCKAP1 | NCK-associated protein 1 | 0.0213848 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0213047 |
| SLMAP | sarcolemma associated protein | 0.0212073 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.021138 |
| TPM3 | tropomyosin 3 | 0.0211249 |
| RYK | receptor-like tyrosine kinase | 0.0209987 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0209305 |
| KRT18 | keratin 18, type I | 0.0208356 |
| KRT8 | keratin 8, type II | 0.0207287 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0205612 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0205433 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0205139 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0201429 |
| MKI67 | marker of proliferation Ki-67 | 0.0198937 |
| SMAD3 | SMAD family member 3 | 0.0198475 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0198072 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193859 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0193673 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0193523 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0192575 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.019254 |
| PTMA | prothymosin, alpha | 0.0192501 |
| RBM25 | RNA binding motif protein 25 | 0.0192495 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0191142 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0190427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.0841541 |
| TMSB10 | thymosin beta 10 | -0.0748556 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0703666 |
| FN1 | fibronectin 1 | -0.0546666 |
| RPLP1 | ribosomal protein, large, P1 | -0.0522571 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0516367 |
| FTL | ferritin, light polypeptide | -0.0515451 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0513019 |
| TPM4 | tropomyosin 4 | -0.0489412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0453963 |
| ACTG1 | actin gamma 1 | -0.0451082 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0433925 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0377694 |
| RPL31 | ribosomal protein L31 | -0.0366822 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.036294 |
| INTS6 | integrator complex subunit 6 | -0.0347754 |
| MYO1E | myosin IE | -0.0339669 |
| SYT14 | synaptotagmin XIV | -0.0333128 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0314175 |
| RPS19 | ribosomal protein S19 | -0.0310653 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303164 |
| SVIL | supervillin | -0.0298737 |
| KRT19 | keratin 19, type I | -0.0291744 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289016 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0288612 |
| RPS6 | ribosomal protein S6 | -0.0284419 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0267895 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0261198 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.025819 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0254762 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.02501 |
| SP100 | SP100 nuclear antigen | -0.0249868 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.024984 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0248557 |
| RPS24 | ribosomal protein S24 | -0.0244268 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239549 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236896 |
| MX2 | MX dynamin-like GTPase 2 | -0.0236844 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0233918 |
| RNF213 | ring finger protein 213 | -0.0227376 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0225333 |
| RPL23 | ribosomal protein L23 | -0.0225236 |
| MX1 | MX dynamin-like GTPase 1 | -0.0222633 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0220314 |
| RIGI | RNA sensor RIG-I | -0.0219558 |
| MT2A | metallothionein 2A | -0.0217928 |
| RPL19 | ribosomal protein L19 | -0.0212392 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0204505 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0202041 |
| CCND1 | cyclin D1 | -0.0194555 |
| VCL | vinculin | -0.0194323 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0193958 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0192441 |
| RPS5 | ribosomal protein S5 | -0.0191263 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0191015 |
| RPS23 | ribosomal protein S23 | -0.0190685 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0183459 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180461 |
| RPL32 | ribosomal protein L32 | -0.0178452 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0178124 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0177418 |
| RPL34 | ribosomal protein L34 | -0.0176399 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0175438 |
| GOLGB1 | golgin B1 | -0.0174923 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0174561 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0173438 |
| HDAC9 | histone deacetylase 9 | -0.0173057 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0171958 |
| RPS25 | ribosomal protein S25 | -0.0170539 |
| RPS14 | ribosomal protein S14 | -0.0170451 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0169709 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0169571 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0169078 |
| BPTF | bromodomain PHD finger transcription factor | -0.0166643 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0165066 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0164898 |
| IFI44L | interferon-induced protein 44-like | -0.0164819 |
| EGFR | epidermal growth factor receptor | -0.0163126 |
| EGR1 | early growth response 1 | -0.0162784 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0160678 |
| THRB | thyroid hormone receptor, beta | -0.0160571 |
| RPS17 | ribosomal protein S17 | -0.0160542 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0157109 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0156048 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0155274 |
| KYNU | kynureninase | -0.0155008 |
| RPS15 | ribosomal protein S15 | -0.0153154 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0151186 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0150467 |
| RPL36A | ribosomal protein L36a | -0.0149526 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0149189 |
| RPS20 | ribosomal protein S20 | -0.0148848 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0148446 |
| RPS27 | ribosomal protein S27 | -0.0147249 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.014642 |
| POTEF | POTE ankyrin domain family, member F | -0.0144836 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0142665 |
| LDHA | lactate dehydrogenase A | -0.01426 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.014225 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0141777 |
