| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.238857 |
| STC1 | stanniocalcin 1 | 0.0671885 |
| VIM | vimentin | 0.0665191 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0628751 |
| PGK1 | phosphoglycerate kinase 1 | 0.0575858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0515234 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0513857 |
| ANXA2 | annexin A2 | 0.0505966 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0502387 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0486929 |
| ZNF292 | zinc finger protein 292 | 0.0433464 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0430044 |
| ENO1 | enolase 1, (alpha) | 0.0426558 |
| NDRG1 | N-myc downstream regulated 1 | 0.0420077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0408924 |
| COL1A2 | collagen, type I, alpha 2 | 0.0400348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0393659 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0391264 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383952 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0378946 |
| AHNAK | AHNAK nucleoprotein | 0.0375189 |
| CD44 | CD44 molecule (Indian blood group) | 0.0367808 |
| CALU | calumenin | 0.0363603 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0353029 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0331749 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0325774 |
| GOLGA4 | golgin A4 | 0.0324835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0312424 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0311382 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0303671 |
| B2M | beta-2-microglobulin | 0.0301954 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0296073 |
| PTMA | prothymosin, alpha | 0.0283351 |
| CALR | calreticulin | 0.0280619 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0279561 |
| CD109 | CD109 molecule | 0.0278678 |
| CANX | calnexin | 0.0276397 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0267905 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0264163 |
| VEGFA | vascular endothelial growth factor A | 0.02549 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0251799 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0248334 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0247803 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0246732 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0245379 |
| RBM39 | RNA binding motif protein 39 | 0.0244922 |
| FAM13A | family with sequence similarity 13, member A | 0.0241014 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0240204 |
| RTN4 | reticulon 4 | 0.0234999 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0227962 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0227929 |
| RLF | rearranged L-myc fusion | 0.0226631 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0224225 |
| ANLN | anillin, actin binding protein | 0.022161 |
| THBS1 | thrombospondin 1 | 0.0219338 |
| H1-0 | H1.0 linker histone | 0.0217859 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0216016 |
| INHBA | inhibin, beta A | 0.0209195 |
| QKI | QKI, KH domain containing, RNA binding | 0.0206765 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0206518 |
| RPS8 | ribosomal protein S8 | 0.0198088 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.019571 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0193923 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0193222 |
| ATP13A3 | ATPase type 13A3 | 0.0190129 |
| OGA | O-GlcNAcase | 0.0189777 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0187403 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0187068 |
| XPO1 | exportin 1 | 0.0186436 |
| USP3 | ubiquitin specific peptidase 3 | 0.0186364 |
| FMNL2 | formin-like 2 | 0.0186112 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.018559 |
| LOXL2 | lysyl oxidase-like 2 | 0.0183261 |
| ARRDC3 | arrestin domain containing 3 | 0.0182942 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0182734 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0182164 |
| UBC | ubiquitin C | 0.0180108 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0179834 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0179452 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0179219 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0177778 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0176079 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0174561 |
| HLA-C | major histocompatibility complex, class I, C | 0.0173809 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0172266 |
| COL1A1 | collagen, type I, alpha 1 | 0.0171967 |
| TFG | TRK-fused gene | 0.0170834 |
| MEF2A | myocyte enhancer factor 2A | 0.0169429 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0169412 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0169378 |
| HELZ | helicase with zinc finger | 0.0169298 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.016828 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0168053 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0167886 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0167282 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0167128 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0166349 |
| SETD5 | SET domain containing 5 | 0.0165978 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0164701 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0164146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0271037 |
| FTL | ferritin, light polypeptide | -0.0197486 |
| MT2A | metallothionein 2A | -0.0176528 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00972777 |
| EGR1 | early growth response 1 | -0.00971797 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.00854994 |
| SHISA5 | shisa family member 5 | -0.00849447 |
| VCL | vinculin | -0.00834762 |
| IFI44L | interferon-induced protein 44-like | -0.00817274 |
| CST3 | cystatin C | -0.00816289 |
| SVIL | supervillin | -0.00798857 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0076001 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0068246 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00679225 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0066318 |
| COL5A3 | collagen, type V, alpha 3 | -0.00640123 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00609899 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00604957 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0057459 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.00549831 |
| IFI44 | interferon-induced protein 44 | -0.00530369 |
| TAPBP | TAP binding protein (tapasin) | -0.0052322 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.00495588 |
| CCDC138 | coiled-coil domain containing 138 | -0.00481217 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.00445213 |
| MT1X | metallothionein 1X | -0.0042185 |
| PMP22 | peripheral myelin protein 22 | -0.00400091 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.003981 |
| RPLP1 | ribosomal protein, large, P1 | -0.00397354 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.00393779 |
| C1R | complement component 1, r subcomponent | -0.00387032 |
| HPCAL1 | hippocalcin-like 1 | -0.00385859 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0038477 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.00370595 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.00362745 |
| CA9 | carbonic anhydrase IX | -0.00360609 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00359994 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00359047 |
| RPL31 | ribosomal protein L31 | -0.00358757 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00355154 |
| DOCK5 | dedicator of cytokinesis 5 | -0.00354402 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00354097 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0035278 |
| BPTF | bromodomain PHD finger transcription factor | -0.00351532 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 | -0.00350842 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.00340278 |
| SKIL | SKI-like proto-oncogene | -0.00338487 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0033678 |
| PRMT2 | protein arginine methyltransferase 2 | -0.00336056 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.00335381 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00334907 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00329388 |
| NBEA | neurobeachin | -0.00329315 |
| PCDHGA2 | protocadherin gamma subfamily A, 2 | -0.00327614 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.00326875 |
| SIK2 | salt-inducible kinase 2 | -0.0032634 |
| PALLD | palladin, cytoskeletal associated protein | -0.00325853 |
| BDKRB2 | bradykinin receptor B2 | -0.00325695 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00325293 |
| SCHIP1 | schwannomin interacting protein 1 | -0.00319218 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | -0.00317851 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.00315168 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | -0.00314027 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00313916 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00313142 |
| USP8 | ubiquitin specific peptidase 8 | -0.00310076 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 | -0.00308639 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0030722 |
| MYADM | myeloid-associated differentiation marker | -0.00306395 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.00306153 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.00301955 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | -0.00301858 |
| MAU2 | MAU2 sister chromatid cohesion factor | -0.00300376 |
| HMGA1 | high mobility group AT-hook 1 | -0.00299861 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | -0.00299472 |
| DOCK6 | dedicator of cytokinesis 6 | -0.00298117 |
| AEBP2 | AE binding protein 2 | -0.00296846 |
| FHL2 | four and a half LIM domains 2 | -0.00294676 |
| PAX3 | paired box 3 | -0.00294379 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.00293144 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.00292442 |
| NIPAL3 | NIPA-like domain containing 3 | -0.00288977 |
| TP63 | tumor protein p63 | -0.00288497 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.00288396 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.00287743 |
| SYT1 | synaptotagmin I | -0.00287099 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.00286773 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00284645 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.00282978 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.00282884 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.00282835 |
| PLBD2 | phospholipase B domain containing 2 | -0.00281334 |
| OPHN1 | oligophrenin 1 | -0.00279933 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.00279843 |
| THADA | thyroid adenoma associated | -0.00277629 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.0027645 |
| GRAMD1B | GRAM domain containing 1B | -0.00276043 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.00275524 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | -0.00274353 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00273572 |
