| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.144467 |
| FN1 | fibronectin 1 | 0.131076 |
| VEGFA | vascular endothelial growth factor A | 0.0767793 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0732635 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0672769 |
| AHNAK | AHNAK nucleoprotein | 0.0626514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0593335 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0582942 |
| NAV2 | neuron navigator 2 | 0.0573578 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0506388 |
| FLNA | filamin A, alpha | 0.0472864 |
| OGA | O-GlcNAcase | 0.0444543 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0444059 |
| ANXA2 | annexin A2 | 0.0443718 |
| SMAD3 | SMAD family member 3 | 0.0435284 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0430318 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0404439 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0403177 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0400143 |
| SPAG9 | sperm associated antigen 9 | 0.0399591 |
| CD44 | CD44 molecule (Indian blood group) | 0.0382583 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382513 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0368894 |
| SDC4 | syndecan 4 | 0.0365767 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0358035 |
| TMSB4X | thymosin beta 4, X-linked | 0.0353528 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0349841 |
| AFDN | afadin, adherens junction formation factor | 0.0329994 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0329816 |
| PDE10A | phosphodiesterase 10A | 0.0321092 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308225 |
| HLA-C | major histocompatibility complex, class I, C | 0.0306303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.030436 |
| ARRDC3 | arrestin domain containing 3 | 0.0299282 |
| APP | amyloid beta (A4) precursor protein | 0.0296422 |
| ANLN | anillin, actin binding protein | 0.029301 |
| ATP13A3 | ATPase type 13A3 | 0.0288833 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0286761 |
| ZNF292 | zinc finger protein 292 | 0.0285805 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0277034 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0274714 |
| ATXN1 | ataxin 1 | 0.0272035 |
| HELZ | helicase with zinc finger | 0.0257466 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0255463 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0254051 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0249535 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0245674 |
| MKI67 | marker of proliferation Ki-67 | 0.024464 |
| DENND5A | DENN/MADD domain containing 5A | 0.0243953 |
| VCAN | versican | 0.0241147 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0239812 |
| RPS3 | ribosomal protein S3 | 0.0239004 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.023894 |
| FNIP1 | folliculin interacting protein 1 | 0.0235989 |
| CADM1 | cell adhesion molecule 1 | 0.0233315 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0230702 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0227071 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0224949 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0222681 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0220966 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0220844 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0217481 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0217204 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0214343 |
| MYOF | myoferlin | 0.0210503 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020307 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0197478 |
| SBF2 | SET binding factor 2 | 0.0197026 |
| KLF6 | Kruppel-like factor 6 | 0.0194349 |
| FLNB | filamin B, beta | 0.019178 |
| COL5A1 | collagen, type V, alpha 1 | 0.0188683 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0187791 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.018585 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0184753 |
| CDK19 | cyclin-dependent kinase 19 | 0.0180437 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0180391 |
| UVRAG | UV radiation resistance associated | 0.0178435 |
| NCKAP1 | NCK-associated protein 1 | 0.0177748 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0176795 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0173976 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0173854 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.017343 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0172973 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0172828 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0172149 |
| TPM3 | tropomyosin 3 | 0.0170098 |
| THBS1 | thrombospondin 1 | 0.0169297 |
| WAC | WW domain containing adaptor with coiled-coil | 0.016917 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0169071 |
| TEX10 | testis expressed 10 | 0.0168759 |
| TNS3 | tensin 3 | 0.0167778 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0167219 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0166903 |
| THBS2 | thrombospondin 2 | 0.0166584 |
| RPS2 | ribosomal protein S2 | 0.0164677 |
| CALU | calumenin | 0.0164142 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0164091 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0162965 |
| MSN | moesin | 0.0162511 |
| ERBIN | erbb2 interacting protein | 0.0161099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.180792 |
| FTL | ferritin, light polypeptide | -0.0967336 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0891608 |
| TMSB10 | thymosin beta 10 | -0.064899 |
| IER3 | immediate early response 3 | -0.0469006 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0459415 |
| EGR1 | early growth response 1 | -0.0369451 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0355894 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0353732 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0341464 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0329709 |
| PLIN2 | perilipin 2 | -0.0325217 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0317415 |
| CTSD | cathepsin D | -0.0288399 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0278925 |
| RPS24 | ribosomal protein S24 | -0.0259969 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0243977 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240083 |
| TAPBP | TAP binding protein (tapasin) | -0.0236088 |
| RPS6 | ribosomal protein S6 | -0.023317 |
| LDHA | lactate dehydrogenase A | -0.0229302 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.022405 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0215605 |
| VCL | vinculin | -0.021539 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0213574 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0210021 |
| RPLP1 | ribosomal protein, large, P1 | -0.0203858 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0196783 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0181551 |
| HMGA1 | high mobility group AT-hook 1 | -0.0180277 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0176673 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0175115 |
| RPS23 | ribosomal protein S23 | -0.0174189 |
| PTMA | prothymosin, alpha | -0.0170728 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0168993 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0162492 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0161051 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0159528 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0151424 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0146948 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0140592 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0140536 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0138737 |
| HLA-B | major histocompatibility complex, class I, B | -0.013782 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0137575 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0132932 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0131363 |
| IER2 | immediate early response 2 | -0.0130931 |
| LOX | lysyl oxidase | -0.0130761 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0130721 |
| S100A9 | S100 calcium binding protein A9 | -0.0125066 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0124168 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0123838 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0116503 |
| RPL31 | ribosomal protein L31 | -0.0116281 |
| TXNIP | thioredoxin interacting protein | -0.0114589 |
| ASPH | aspartate beta-hydroxylase | -0.0114308 |
| RIGI | RNA sensor RIG-I | -0.0114095 |
| MORF4L2 | mortality factor 4 like 2 | -0.0112687 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0109803 |
| KYNU | kynureninase | -0.0109223 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0108891 |
| TRIM5 | tripartite motif containing 5 | -0.0108785 |
| FRMD4A | FERM domain containing 4A | -0.0107221 |
| RPS14 | ribosomal protein S14 | -0.0105428 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0104341 |
| SP100 | SP100 nuclear antigen | -0.0100183 |
| WBP2 | WW domain binding protein 2 | -0.00989494 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00988972 |
| MX1 | MX dynamin-like GTPase 1 | -0.00947882 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00946714 |
| RPL23 | ribosomal protein L23 | -0.00942584 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.00938717 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00933001 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0092386 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00903361 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00895524 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00880342 |
| GOLGB1 | golgin B1 | -0.00874653 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00868958 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00868418 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00858069 |
| NRN1 | neuritin 1 | -0.00856739 |
| NOL7 | nucleolar protein 7, 27kDa | -0.00856705 |
| IL6 | interleukin 6 | -0.00854943 |
| WWOX | WW domain containing oxidoreductase | -0.0084882 |
| NCKAP5 | NCK-associated protein 5 | -0.00844762 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00840093 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.00839304 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00835931 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00830982 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00822658 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00822211 |
| CDK6 | cyclin-dependent kinase 6 | -0.00814678 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00813555 |
| RPS19 | ribosomal protein S19 | -0.00809185 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0080914 |
| MX2 | MX dynamin-like GTPase 2 | -0.00805735 |
| MAGT1 | magnesium transporter 1 | -0.0080372 |
| WDR45B | WD repeat domain 45B | -0.00795869 |
