| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0952264 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0710238 |
| FNDC3B | fibronectin type III domain containing 3B | 0.05792 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.054541 |
| VEGFA | vascular endothelial growth factor A | 0.0540297 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0499339 |
| FN1 | fibronectin 1 | 0.0498476 |
| CD109 | CD109 molecule | 0.0476451 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0469606 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0455183 |
| ZNF292 | zinc finger protein 292 | 0.0442344 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0433866 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0416936 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0397464 |
| NDRG1 | N-myc downstream regulated 1 | 0.038442 |
| NRP1 | neuropilin 1 | 0.03795 |
| FAM13A | family with sequence similarity 13, member A | 0.0371048 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0363457 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0357819 |
| TMEM156 | transmembrane protein 156 | 0.034341 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335661 |
| PTK2 | protein tyrosine kinase 2 | 0.0334731 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0329377 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0329169 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318921 |
| PELO | pelota homolog (Drosophila) | 0.0318001 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0314097 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0303097 |
| SMAD3 | SMAD family member 3 | 0.0299321 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0296173 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0294551 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286252 |
| MT2A | metallothionein 2A | 0.0282183 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0281051 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0278368 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0276017 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0274826 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274366 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0272721 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0269811 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0269663 |
| ITGA1 | integrin, alpha 1 | 0.0266525 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0265213 |
| GOLGA4 | golgin A4 | 0.0260908 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0259166 |
| RUNX2 | runt-related transcription factor 2 | 0.0257951 |
| HELZ | helicase with zinc finger | 0.0256485 |
| AHR | aryl hydrocarbon receptor | 0.0251373 |
| TPR | translocated promoter region, nuclear basket protein | 0.0247033 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0245968 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0245756 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0244908 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0243272 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0242939 |
| CENPF | centromere protein F, 350/400kDa | 0.0242089 |
| NUP58 | nucleoporin 58 | 0.0239968 |
| PRELID2 | PRELI domain containing 2 | 0.0238636 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.023723 |
| OGA | O-GlcNAcase | 0.0231839 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0231458 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.0228026 |
| ETNK1 | ethanolamine kinase 1 | 0.0222177 |
| OSMR | oncostatin M receptor | 0.0218704 |
| CDC73 | cell division cycle 73 | 0.0216785 |
| FAT1 | FAT atypical cadherin 1 | 0.0215785 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0212605 |
| CAB39 | calcium binding protein 39 | 0.0210585 |
| TPM3 | tropomyosin 3 | 0.0210396 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0208388 |
| ADAR | adenosine deaminase, RNA-specific | 0.0205951 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0203986 |
| SPAG9 | sperm associated antigen 9 | 0.0202713 |
| RTN4 | reticulon 4 | 0.020226 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.02012 |
| CD44 | CD44 molecule (Indian blood group) | 0.0200729 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0200158 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0199991 |
| RUNX1 | runt-related transcription factor 1 | 0.0199697 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0199102 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0198878 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.019853 |
| AFDN | afadin, adherens junction formation factor | 0.0197551 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0196812 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0195267 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0195141 |
| FOSL1 | FOS-like antigen 1 | 0.0194336 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0192068 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0188387 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0188357 |
| FLNA | filamin A, alpha | 0.0188272 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0187912 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0187829 |
| PCBP2 | poly(rC) binding protein 2 | 0.0185489 |
| HDGF | hepatoma-derived growth factor | 0.018527 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0185138 |
| RNF145 | ring finger protein 145 | 0.0184052 |
| SMOX | spermine oxidase | 0.0183945 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0182457 |
| SLTM | SAFB-like, transcription modulator | 0.0181629 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0181305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0823257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0815282 |
| TMSB10 | thymosin beta 10 | -0.0607977 |
| FTL | ferritin, light polypeptide | -0.0545302 |
| PTMA | prothymosin, alpha | -0.0492433 |
| NRG1 | neuregulin 1 | -0.0461174 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.034605 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0342766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0321022 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0317347 |
| SQSTM1 | sequestosome 1 | -0.029711 |
| LMNA | lamin A/C | -0.0289165 |
| S100A10 | S100 calcium binding protein A10 | -0.0262338 |
| S100A6 | S100 calcium binding protein A6 | -0.0254126 |
| INTS6 | integrator complex subunit 6 | -0.0249768 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232176 |
| RPLP1 | ribosomal protein, large, P1 | -0.0230735 |
| AEBP2 | AE binding protein 2 | -0.022764 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0225011 |
| RPS24 | ribosomal protein S24 | -0.0217109 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0214556 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0213677 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0211474 |
| IER3 | immediate early response 3 | -0.0204229 |
| PALLD | palladin, cytoskeletal associated protein | -0.0188837 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0182185 |
| VCL | vinculin | -0.0180337 |
| RPL31 | ribosomal protein L31 | -0.0180181 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0176239 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0172982 |
| VIM | vimentin | -0.0172909 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0167335 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0164194 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0159938 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0156891 |
| LRRC23 | leucine rich repeat containing 23 | -0.0149962 |
| DSTN | destrin (actin depolymerizing factor) | -0.0139189 |
| RPS20 | ribosomal protein S20 | -0.0138335 |
| ARF1 | ADP-ribosylation factor 1 | -0.0136856 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0125894 |
| SFRP1 | secreted frizzled-related protein 1 | -0.012225 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.011627 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0115719 |
| GNAS | GNAS complex locus | -0.0115356 |
| TENM4 | teneurin transmembrane protein 4 | -0.010991 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0108783 |
| MMP13 | matrix metallopeptidase 13 | -0.0107389 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.010674 |
| NPR2 | natriuretic peptide receptor 2 | -0.0105381 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0104548 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0104478 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0101403 |
| ATF3 | activating transcription factor 3 | -0.0101028 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0100029 |
| ASPH | aspartate beta-hydroxylase | -0.00993719 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00982727 |
| RPL34 | ribosomal protein L34 | -0.00980501 |
| CTSD | cathepsin D | -0.0097126 |
| CD63 | CD63 molecule | -0.00958179 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.00948253 |
| CCDC138 | coiled-coil domain containing 138 | -0.00942605 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00935339 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0093151 |
| TMSB4X | thymosin beta 4, X-linked | -0.00930997 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00927932 |
| EGR1 | early growth response 1 | -0.00925128 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0090049 |
| JUN | jun proto-oncogene | -0.00892408 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00884619 |
| ACTG1 | actin gamma 1 | -0.00882426 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.00879227 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00879097 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00853592 |
| ABLIM1 | actin binding LIM protein 1 | -0.00852518 |
| RPL32 | ribosomal protein L32 | -0.0084357 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00841485 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00841 |
| RPL38 | ribosomal protein L38 | -0.0083613 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.00832793 |
| UBB | ubiquitin B | -0.00813952 |
| EZR | ezrin | -0.00804238 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00800863 |
| RPS21 | ribosomal protein S21 | -0.00793525 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00789791 |
| CUX1 | cut-like homeobox 1 | -0.007849 |
| POU2F2 | POU class 2 homeobox 2 | -0.00784019 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00781941 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.00778313 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00776347 |
| FBN1 | fibrillin 1 | -0.00775057 |
| RTN3 | reticulon 3 | -0.00772035 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00771956 |
| CANX | calnexin | -0.00766412 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.00765928 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.0076357 |
| RPS5 | ribosomal protein S5 | -0.00755605 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00752703 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.00741966 |
| CDK13 | cyclin-dependent kinase 13 | -0.00739875 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00738721 |
