| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA1 | annexin A1 | 0.0774208 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0749384 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0703034 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0493659 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0472987 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0409031 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0406417 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0401703 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0397316 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0394569 |
| PTMA | prothymosin, alpha | 0.0389667 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0386505 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0381487 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.037188 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0355705 |
| NUP58 | nucleoporin 58 | 0.0350595 |
| ANXA2 | annexin A2 | 0.034777 |
| DSPP | dentin sialophosphoprotein | 0.0341912 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0335539 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315375 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0307757 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0302526 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0293775 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0289682 |
| NCKAP1 | NCK-associated protein 1 | 0.0285996 |
| MYO5B | myosin VB | 0.0281102 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0277237 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0270227 |
| EPHA2 | EPH receptor A2 | 0.0269488 |
| ZNF292 | zinc finger protein 292 | 0.0261496 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0261066 |
| BRD2 | bromodomain containing 2 | 0.0258061 |
| PARD3 | par-3 family cell polarity regulator | 0.0256009 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0251309 |
| FBXO11 | F-box protein 11 | 0.0250509 |
| RPL3 | ribosomal protein L3 | 0.0249097 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0245963 |
| RPS2 | ribosomal protein S2 | 0.0243511 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.023856 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0238001 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0236137 |
| RNF145 | ring finger protein 145 | 0.0233617 |
| AREG | amphiregulin | 0.0231801 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.023169 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0229939 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0229734 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0229189 |
| USP3 | ubiquitin specific peptidase 3 | 0.0227799 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0223836 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0220522 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0220265 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0219069 |
| RPS3 | ribosomal protein S3 | 0.0216902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02168 |
| FMNL2 | formin-like 2 | 0.0212754 |
| NDRG1 | N-myc downstream regulated 1 | 0.0212732 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0211991 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0210971 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0210881 |
| CCNL1 | cyclin L1 | 0.0210469 |
| VMP1 | vacuole membrane protein 1 | 0.0210438 |
| RBM39 | RNA binding motif protein 39 | 0.0210292 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0210291 |
| VEGFA | vascular endothelial growth factor A | 0.0208242 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0207646 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0207515 |
| RPS12 | ribosomal protein S12 | 0.0206965 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.020554 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0198431 |
| RLF | rearranged L-myc fusion | 0.0198212 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0198191 |
| RPL5 | ribosomal protein L5 | 0.0197554 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0194225 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.019405 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.019072 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0190269 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0188499 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0188454 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0188329 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0188272 |
| FAT1 | FAT atypical cadherin 1 | 0.0188124 |
| RUNX2 | runt-related transcription factor 2 | 0.0187169 |
| SETD5 | SET domain containing 5 | 0.018525 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0183991 |
| PUM2 | pumilio RNA-binding family member 2 | 0.01829 |
| GOLGA4 | golgin A4 | 0.018068 |
| TXNIP | thioredoxin interacting protein | 0.0180017 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0179956 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0179264 |
| UBC | ubiquitin C | 0.0178655 |
| RCOR1 | REST corepressor 1 | 0.0176678 |
| MYO1B | myosin IB | 0.0175886 |
| DIAPH1 | diaphanous-related formin 1 | 0.0175312 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.017516 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0175058 |
| YTHDC1 | YTH domain containing 1 | 0.017426 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0174177 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173579 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0172712 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0172454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0741827 |
| HMGA2 | high mobility group AT-hook 2 | -0.0684414 |
| LMO7 | LIM domain 7 | -0.0516596 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0506281 |
| TMSB10 | thymosin beta 10 | -0.0430989 |
| FERMT1 | fermitin family member 1 | -0.0377558 |
| EGFR | epidermal growth factor receptor | -0.0341793 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0306632 |
| RPLP1 | ribosomal protein, large, P1 | -0.029842 |
| RPS24 | ribosomal protein S24 | -0.0296888 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0274399 |
| ACTG1 | actin gamma 1 | -0.026389 |
| RBM25 | RNA binding motif protein 25 | -0.0255449 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.024653 |
| RNF43 | ring finger protein 43 | -0.0241533 |
| CENPF | centromere protein F, 350/400kDa | -0.0234095 |
| LAMC2 | laminin, gamma 2 | -0.0231309 |
| VCL | vinculin | -0.0218172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0208142 |
| MKI67 | marker of proliferation Ki-67 | -0.0187546 |
| SMYD3 | SET and MYND domain containing 3 | -0.018128 |
| FLOT1 | flotillin 1 | -0.0179389 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0174193 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0172358 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0169922 |
| TCF12 | transcription factor 12 | -0.0167942 |
| CDCP1 | CUB domain containing protein 1 | -0.0165148 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0164734 |
| MTAP | methylthioadenosine phosphorylase | -0.0164094 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0164028 |
| RAD51B | RAD51 paralog B | -0.0162509 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0162202 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0159238 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0159088 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0154551 |
| DUSP4 | dual specificity phosphatase 4 | -0.0151678 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0147809 |
| LAMB3 | laminin, beta 3 | -0.0147341 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0146648 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0145301 |
| CENPE | centromere protein E, 312kDa | -0.0144679 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0144108 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0143824 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0143822 |
| FHL2 | four and a half LIM domains 2 | -0.014179 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0137589 |
| ATXN1 | ataxin 1 | -0.0136969 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0135859 |
| RPL4 | ribosomal protein L4 | -0.0134734 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0133105 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0133004 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0132503 |
| RPS28 | ribosomal protein S28 | -0.013171 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0131281 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0131273 |
| KIZ | kizuna centrosomal protein | -0.0130785 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0130753 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0128679 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0128267 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0127614 |
| EXOC4 | exocyst complex component 4 | -0.0126393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0122854 |
| SEPTIN9 | septin 9 | -0.0122197 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0121079 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.011901 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0116513 |
| S100A6 | S100 calcium binding protein A6 | -0.0116022 |
| RPS21 | ribosomal protein S21 | -0.0115944 |
| HDLBP | high density lipoprotein binding protein | -0.0114845 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0114135 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0114087 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0113591 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0112148 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0111758 |
| EXPH5 | exophilin 5 | -0.011066 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0109994 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0109609 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0109166 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0108921 |
| RPL36A | ribosomal protein L36a | -0.0108382 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0108291 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0107218 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0106915 |
| ZNF106 | zinc finger protein 106 | -0.0106735 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0105151 |
| NEBL | nebulette | -0.0104755 |
| SPATA13 | spermatogenesis associated 13 | -0.0104618 |
| PFKP | phosphofructokinase, platelet | -0.0104004 |
| UTRN | utrophin | -0.0103621 |
| TPM4 | tropomyosin 4 | -0.0103463 |
| PDS5A | PDS5 cohesin associated factor A | -0.0103459 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0103283 |
| EZR | ezrin | -0.0103267 |
| SMAD3 | SMAD family member 3 | -0.0102646 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0102525 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0102484 |
| TGFB2 | transforming growth factor, beta 2 | -0.0101989 |
| TNS3 | tensin 3 | -0.0101971 |
| CMIP | c-Maf inducing protein | -0.0101959 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0101659 |
