| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.186429 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.104937 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0760574 |
| SYT1 | synaptotagmin I | 0.0617789 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0586546 |
| ATXN1 | ataxin 1 | 0.0582262 |
| RUNX1 | runt-related transcription factor 1 | 0.0554996 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0541142 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0535091 |
| AHNAK | AHNAK nucleoprotein | 0.0516762 |
| NAV2 | neuron navigator 2 | 0.0515058 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0511082 |
| DST | dystonin | 0.0491843 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0470698 |
| DSPP | dentin sialophosphoprotein | 0.0456577 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0442915 |
| TNS3 | tensin 3 | 0.0442575 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0431891 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.042739 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0415142 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0394934 |
| ENO1 | enolase 1, (alpha) | 0.0393473 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.039104 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0383039 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0377398 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0371428 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0365601 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0364729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0361013 |
| LMO7 | LIM domain 7 | 0.0359792 |
| PROX1 | prospero homeobox 1 | 0.0356063 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0353248 |
| MKI67 | marker of proliferation Ki-67 | 0.0351862 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0349422 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0349341 |
| ANLN | anillin, actin binding protein | 0.0342855 |
| AOPEP | aminopeptidase O (putative) | 0.0342338 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0341708 |
| ANXA2 | annexin A2 | 0.0341025 |
| KRT18 | keratin 18, type I | 0.0335625 |
| KRT8 | keratin 8, type II | 0.0333894 |
| OXR1 | oxidation resistance 1 | 0.0330285 |
| TMEM123 | transmembrane protein 123 | 0.0326712 |
| ITGA6 | integrin, alpha 6 | 0.0324844 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0324419 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0320355 |
| TMSB4X | thymosin beta 4, X-linked | 0.0319819 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0313273 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0312231 |
| SBF2 | SET binding factor 2 | 0.0307698 |
| CDK6 | cyclin-dependent kinase 6 | 0.0304525 |
| MED13 | mediator complex subunit 13 | 0.0303352 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0301993 |
| WWOX | WW domain containing oxidoreductase | 0.0297498 |
| HDAC4 | histone deacetylase 4 | 0.0295724 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0292621 |
| PGK1 | phosphoglycerate kinase 1 | 0.0289624 |
| EFNB2 | ephrin-B2 | 0.0289327 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0283122 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0282825 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0281765 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0280323 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0279508 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278898 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0278559 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0277231 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0272738 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0272361 |
| ZNF292 | zinc finger protein 292 | 0.0269433 |
| HDAC8 | histone deacetylase 8 | 0.0268276 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0266854 |
| SPATA13 | spermatogenesis associated 13 | 0.0265771 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0265614 |
| BCL2L1 | BCL2-like 1 | 0.0265202 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0264081 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0257326 |
| BPTF | bromodomain PHD finger transcription factor | 0.0251772 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251744 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0250476 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0249635 |
| FOXP1 | forkhead box P1 | 0.0248142 |
| ETNK1 | ethanolamine kinase 1 | 0.0247694 |
| VIM | vimentin | 0.0246885 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0244364 |
| RAD51B | RAD51 paralog B | 0.0243734 |
| NF1 | neurofibromin 1 | 0.0239566 |
| JMJD1C | jumonji domain containing 1C | 0.0237719 |
| ACTN4 | actinin, alpha 4 | 0.0237179 |
| YAP1 | Yes-associated protein 1 | 0.0236832 |
| SMYD3 | SET and MYND domain containing 3 | 0.0236079 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0235614 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0234577 |
| APP | amyloid beta (A4) precursor protein | 0.0234346 |
| CDH13 | cadherin 13 | 0.0233279 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0233243 |
| EZR | ezrin | 0.0230206 |
| TMEM163 | transmembrane protein 163 | 0.0228375 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0227031 |
| CMIP | c-Maf inducing protein | 0.0227029 |
| KIZ | kizuna centrosomal protein | 0.022677 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.032333 |
| MT2A | metallothionein 2A | -0.023785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0194148 |
| RPS19 | ribosomal protein S19 | -0.0187334 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0151478 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0147986 |
| RPL35A | ribosomal protein L35a | -0.0144108 |
| INTS6 | integrator complex subunit 6 | -0.0137725 |
| TMSB10 | thymosin beta 10 | -0.0128652 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0127553 |
| MT1X | metallothionein 1X | -0.01263 |
| EGR1 | early growth response 1 | -0.0120311 |
| RPL12 | ribosomal protein L12 | -0.0101695 |
| IGF2 | insulin-like growth factor 2 | -0.00903912 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00846473 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00838764 |
| RPL18 | ribosomal protein L18 | -0.00806511 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.00796713 |
| UBAP2 | ubiquitin associated protein 2 | -0.00757519 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00736712 |
| RPS6 | ribosomal protein S6 | -0.00732308 |
| POTEF | POTE ankyrin domain family, member F | -0.00706206 |
| RPS29 | ribosomal protein S29 | -0.00672094 |
| RPS23 | ribosomal protein S23 | -0.0067066 |
| DHFR | dihydrofolate reductase | -0.0066299 |
| SEC61G | Sec61 gamma subunit | -0.00652249 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0063818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00636764 |
| RPL36 | ribosomal protein L36 | -0.00611616 |
| PER1 | period circadian clock 1 | -0.00600987 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0059985 |
| RPL23 | ribosomal protein L23 | -0.00583502 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.005781 |
| RPL21 | ribosomal protein L21 | -0.00572917 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00572895 |
| HMGA1 | high mobility group AT-hook 1 | -0.00565106 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00564527 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00561562 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00559829 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00552988 |
| RNF145 | ring finger protein 145 | -0.0054891 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00535351 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00534006 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00530305 |
| RPS3 | ribosomal protein S3 | -0.00528896 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00519272 |
| NOP58 | NOP58 ribonucleoprotein | -0.00517644 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00509645 |
| FOSL2 | FOS-like antigen 2 | -0.00505502 |
| RPL34 | ribosomal protein L34 | -0.00499842 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.00494141 |
| RPS14 | ribosomal protein S14 | -0.00490869 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00485338 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.00482522 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00476421 |
| CLSTN2 | calsyntenin 2 | -0.00474876 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.00472627 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.00460179 |
| FTL | ferritin, light polypeptide | -0.00458134 |
| ROMO1 | reactive oxygen species modulator 1 | -0.00452298 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.00451475 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.00442856 |
| CALR | calreticulin | -0.00434549 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.00433031 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.0042516 |
| ANKRD37 | ankyrin repeat domain 37 | -0.00420221 |
| BAIAP2 | BAI1-associated protein 2 | -0.00420119 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.00417215 |
| TGFB1 | transforming growth factor, beta 1 | -0.00416798 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00410025 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0040714 |
| RPL27 | ribosomal protein L27 | -0.00406805 |
| TOB1 | transducer of ERBB2, 1 | -0.00405886 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | -0.00397614 |
| FAM107B | family with sequence similarity 107, member B | -0.00397186 |
| IER3 | immediate early response 3 | -0.00396554 |
| PCBP3 | poly(rC) binding protein 3 | -0.00395332 |
| KIAA0930 | KIAA0930 | -0.00392058 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.00390319 |
| ADAM20 | ADAM metallopeptidase domain 20 | -0.00390285 |
| RPS10 | ribosomal protein S10 | -0.00388961 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.00388826 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | -0.00386844 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00385914 |
| TGM2 | transglutaminase 2 | -0.00385077 |
| TBCA | tubulin folding cofactor A | -0.00384019 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.00383839 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00382496 |
| SMIM29 | small integral membrane protein 29 | -0.00381832 |
| CADM1 | cell adhesion molecule 1 | -0.0038024 |
| ADM | adrenomedullin | -0.0037995 |
| NGFR | nerve growth factor receptor | -0.0037768 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00373989 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.00373632 |
| NTM | neurotrimin | -0.00372736 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | -0.00372497 |
| SERINC2 | serine incorporator 2 | -0.00372209 |
| ZFP36 | ZFP36 ring finger protein | -0.00371931 |
| S100P | S100 calcium binding protein P | -0.00369917 |
| ARLN | allregulin | -0.00367457 |
