| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.184582 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.163238 |
| VIM | vimentin | 0.111662 |
| FAM13A | family with sequence similarity 13, member A | 0.0951306 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0853862 |
| FN1 | fibronectin 1 | 0.0800823 |
| NDRG1 | N-myc downstream regulated 1 | 0.0797911 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0791277 |
| SPAG9 | sperm associated antigen 9 | 0.0650054 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0533593 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0512271 |
| CALU | calumenin | 0.0506296 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0499223 |
| ADM | adrenomedullin | 0.0467476 |
| CD44 | CD44 molecule (Indian blood group) | 0.0455993 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0453879 |
| GOLGA4 | golgin A4 | 0.0453038 |
| INHBA | inhibin, beta A | 0.0426585 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0405236 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0405182 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0402968 |
| ZNF292 | zinc finger protein 292 | 0.0396438 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0391202 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0382653 |
| ATP13A3 | ATPase type 13A3 | 0.0377599 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0375598 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0362217 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0359441 |
| MT2A | metallothionein 2A | 0.0354618 |
| ANXA2 | annexin A2 | 0.0321502 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0321197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318286 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0316356 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.030965 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288667 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0286539 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.027915 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0273323 |
| B2M | beta-2-microglobulin | 0.0272228 |
| NUP58 | nucleoporin 58 | 0.0269011 |
| ENO1 | enolase 1, (alpha) | 0.0263852 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0261855 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.02613 |
| USP3 | ubiquitin specific peptidase 3 | 0.0258556 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256293 |
| OGA | O-GlcNAcase | 0.024683 |
| TMSB4X | thymosin beta 4, X-linked | 0.0246721 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0246521 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0243782 |
| ARRDC3 | arrestin domain containing 3 | 0.0241774 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0238856 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0236249 |
| CDC27 | cell division cycle 27 | 0.0235519 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0235239 |
| CALR | calreticulin | 0.0231308 |
| RUNX1 | runt-related transcription factor 1 | 0.0230934 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0228131 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0226236 |
| SRGN | serglycin | 0.0225236 |
| COPA | coatomer protein complex, subunit alpha | 0.0225122 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0224382 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0223069 |
| NAV2 | neuron navigator 2 | 0.0219602 |
| LOX | lysyl oxidase | 0.0219245 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0214987 |
| MXI1 | MAX interactor 1, dimerization protein | 0.021422 |
| YBX1 | Y box binding protein 1 | 0.0213427 |
| RAB8B | RAB8B, member RAS oncogene family | 0.021292 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0212818 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0210872 |
| SUCO | SUN domain containing ossification factor | 0.0210729 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0207763 |
| HELZ | helicase with zinc finger | 0.0204008 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0202836 |
| NBAS | neuroblastoma amplified sequence | 0.0199516 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0197939 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.019716 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0196202 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0195373 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0195115 |
| SETD5 | SET domain containing 5 | 0.0195065 |
| RTN4 | reticulon 4 | 0.0194867 |
| YBX3 | Y box binding protein 3 | 0.0194817 |
| CLINT1 | clathrin interactor 1 | 0.0192854 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0192014 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0190947 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0190586 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0190524 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0190438 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0189623 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0189435 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0188852 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0187061 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0186116 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0185774 |
| SEC24D | SEC24 family member D | 0.0184809 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0184609 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0181588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0180903 |
| HMGB2 | high mobility group box 2 | 0.0180258 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.111816 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0957009 |
| COL1A1 | collagen, type I, alpha 1 | -0.0818561 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.071136 |
| HMGA2 | high mobility group AT-hook 2 | -0.0701125 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0592076 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0518437 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0510578 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0463277 |
| COL1A2 | collagen, type I, alpha 2 | -0.0366795 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0351779 |
| MYO10 | myosin X | -0.0347117 |
| VCL | vinculin | -0.0346618 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0333373 |
| TMSB10 | thymosin beta 10 | -0.0319702 |
| OXR1 | oxidation resistance 1 | -0.0307503 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0290838 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0285821 |
| NAV1 | neuron navigator 1 | -0.0270803 |
| ASPH | aspartate beta-hydroxylase | -0.0269152 |
| GLIS3 | GLIS family zinc finger 3 | -0.0266021 |
| CDH13 | cadherin 13 | -0.0262696 |
| FRMD4A | FERM domain containing 4A | -0.0244639 |
| KIAA1549L | KIAA1549-like | -0.0239557 |
| PRRX1 | paired related homeobox 1 | -0.0238087 |
| EGFR | epidermal growth factor receptor | -0.0232869 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0232177 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0211342 |
| FBN1 | fibrillin 1 | -0.0210798 |
| INTS6 | integrator complex subunit 6 | -0.0199575 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0199113 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0196497 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0196314 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0195576 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0191587 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0189988 |
| CLMP | CXADR-like membrane protein | -0.0188979 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0188842 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0187771 |
| DIAPH2 | diaphanous-related formin 2 | -0.0187594 |
| NCKAP5 | NCK-associated protein 5 | -0.0186619 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0185972 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0185464 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0180317 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.017973 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0179445 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.017847 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0177043 |
| RAI14 | retinoic acid induced 14 | -0.0175018 |
| CDK6 | cyclin-dependent kinase 6 | -0.0169043 |
| CUX1 | cut-like homeobox 1 | -0.016745 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0165727 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0165095 |
| DGKI | diacylglycerol kinase, iota | -0.0162752 |
| ACTG1 | actin gamma 1 | -0.0161273 |
| NREP | neuronal regeneration related protein | -0.0159285 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.015819 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0151378 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0150294 |
| RPL31 | ribosomal protein L31 | -0.0149542 |
| MMP1 | matrix metallopeptidase 1 | -0.0147224 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.014702 |
| IGF2 | insulin-like growth factor 2 | -0.0141117 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.014061 |
| RAD51B | RAD51 paralog B | -0.0139924 |
| PRSS23 | protease, serine, 23 | -0.0139577 |
| COL5A1 | collagen, type V, alpha 1 | -0.0136801 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0135654 |
| AEBP2 | AE binding protein 2 | -0.0134231 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0133951 |
| VCAN | versican | -0.0133804 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0133473 |
| EMP1 | epithelial membrane protein 1 | -0.0133336 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0127648 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0126016 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0125262 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.012487 |
| HLA-B | major histocompatibility complex, class I, B | -0.0124363 |
| EGR1 | early growth response 1 | -0.0123186 |
| CCND1 | cyclin D1 | -0.0122615 |
| DTNA | dystrobrevin, alpha | -0.0120943 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0117321 |
| CCDC102B | coiled-coil domain containing 102B | -0.0116329 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0115159 |
| CCDC91 | coiled-coil domain containing 91 | -0.0109873 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0109584 |
| LYST | lysosomal trafficking regulator | -0.0108008 |
| IPO9 | importin 9 | -0.0107822 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.010763 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0106728 |
| FTL | ferritin, light polypeptide | -0.0105607 |
| CA12 | carbonic anhydrase XII | -0.0104869 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0104439 |
| ATG7 | autophagy related 7 | -0.0104023 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0103871 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.0103692 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.010302 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0101582 |
| COL3A1 | collagen, type III, alpha 1 | -0.0101116 |
| MYO1E | myosin IE | -0.0100011 |
