Ruffle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. (Gene Ontology, GO_0001726)
External Link http://amigo.geneontology.org/amigo/term/GO:0001726
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Genes

1000 proteins co-occuring with the Ruffle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CDC42 cell division cycle 42 3.203
RHOA ras homolog family member A 2.912
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.843
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.834
CTTN cortactin 2.821
WASL Wiskott-Aldrich syndrome-like 2.751
WAS Wiskott-Aldrich syndrome 2.716
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.715
ARF6 ADP-ribosylation factor 6 2.659
EGF epidermal growth factor 2.649
RHOG ras homolog family member G 2.622
VCL vinculin 2.585
WASF2 WAS protein family, member 2 2.579
PLEK2 pleckstrin 2 2.572
EZR ezrin 2.564
TIAM1 T-cell lymphoma invasion and metastasis 1 2.557
CFL2 cofilin 2 (muscle) 2.548
PLEK pleckstrin 2.54
RAB5A RAB5A, member RAS oncogene family 2.454
MSN moesin 2.45
FN1 fibronectin 1 2.443
DOCK1 dedicator of cytokinesis 1 2.436
RABIF RAB interacting factor 2.434
MYH14 myosin, heavy chain 14, non-muscle 2.425
RDX radixin 2.397
MCF2 MCF.2 cell line derived transforming sequence 2.38
VASP vasodilator-stimulated phosphoprotein 2.38
TLN1 talin 1 2.367
TLN2 talin 2 2.362
WASF1 WAS protein family, member 1 2.362
FLNA filamin A, alpha 2.361
IQGAP1 IQ motif containing GTPase activating protein 1 2.317
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.296
NCK1 NCK adaptor protein 1 2.293
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.29
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.285
VAV1 vav 1 guanine nucleotide exchange factor 2.282
CLSTN1 calsyntenin 1 2.28
ABI1 abl-interactor 1 2.276
DNM2 dynamin 2 2.264
BAIAP2 BAI1-associated protein 2 2.262
VAV2 vav 2 guanine nucleotide exchange factor 2.259
BCAR1 breast cancer anti-estrogen resistance 1 2.252
EGFR epidermal growth factor receptor 2.25
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.249
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.237
GRB2 growth factor receptor-bound protein 2 2.228
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.225
FSCN1 fascin actin-bundling protein 1 2.222
PTK2 protein tyrosine kinase 2 2.218
ARF1 ADP-ribosylation factor 1 2.198
SLCO6A1 solute carrier organic anion transporter family, member 6A1 2.195
PFN1 profilin 1 2.183
PFN4 profilin family, member 4 2.163
RTKN rhotekin 2.162
PFN3 profilin 3 2.16
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.149
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.129
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.125
ARHGAP35 Rho GTPase activating protein 35 2.108
EPS8 epidermal growth factor receptor pathway substrate 8 2.097
SCIN scinderin 2.095
FLNB filamin B, beta 2.081
GSN gelsolin 2.073
EEA1 early endosome antigen 1 2.065
RHOC ras homolog family member C 2.063
FBF1 Fas (TNFRSF6) binding factor 1 2.058
SPI1 Spi-1 proto-oncogene 2.043
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 2.038
OCRL oculocerebrorenal syndrome of Lowe 2.03
FLNC filamin C, gamma 2.03
KLK4 kallikrein-related peptidase 4 2.008
WIPF1 WAS/WASL interacting protein family, member 1 2.001
LIMK1 LIM domain kinase 1 1.999
RHOB ras homolog family member B 1.999
INPPL1 inositol polyphosphate phosphatase-like 1 1.996
RAB34 RAB34, member RAS oncogene family 1.995
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.987
NEXN nexilin (F actin binding protein) 1.982
WASF3 WAS protein family, member 3 1.98
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.978
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.977
RAB11A RAB11A, member RAS oncogene family 1.966
CAV1 caveolin 1, caveolae protein, 22kDa 1.965
PLCD1 phospholipase C, delta 1 1.963
VAV3 vav 3 guanine nucleotide exchange factor 1.962
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.96
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.954
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.95
SH3PXD2A SH3 and PX domains 2A 1.941
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.935
SNX9 sorting nexin 9 1.933
PXDN peroxidasin 1.931
CD44 CD44 molecule (Indian blood group) 1.931
AMBN ameloblastin (enamel matrix protein) 1.926
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.925
PXDNL peroxidasin-like 1.925
PALLD palladin, cytoskeletal associated protein 1.925
MAPK3 mitogen-activated protein kinase 3 1.917
SOS1 son of sevenless homolog 1 (Drosophila) 1.91
AMPH amphiphysin 1.91
ACTN4 actinin, alpha 4 1.908
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 1.907
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.904
CYTH1 cytohesin 1 1.901
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.901
FBXL15 F-box and leucine-rich repeat protein 15 1.887
ZYX zyxin 1.887
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 1.886
CYTH3 cytohesin 3 1.881
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.881
ARHGAP1 Rho GTPase activating protein 1 1.881
LASP1 LIM and SH3 protein 1 1.875
CYTH2 cytohesin 2 1.867
ERBB2 erb-b2 receptor tyrosine kinase 2 1.866
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.851
BIN1 bridging integrator 1 1.849
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 1.836
ENAM enamelin 1.836
DIAPH3 diaphanous-related formin 3 1.832
SWAP70 SWAP switching B-cell complex 70kDa subunit 1.828
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.824
LYN LYN proto-oncogene, Src family tyrosine kinase 1.821
PLCG1 phospholipase C, gamma 1 1.821
LAMP1 lysosomal-associated membrane protein 1 1.817
NCKIPSD NCK interacting protein with SH3 domain 1.817
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.814
RAB21 RAB21, member RAS oncogene family 1.812
INS insulin 1.804
CLTCL1 clathrin, heavy chain-like 1 1.802
PLD2 phospholipase D2 1.8
RAB8A RAB8A, member RAS oncogene family 1.799
PTK2B protein tyrosine kinase 2 beta 1.799
CSF1 colony stimulating factor 1 (macrophage) 1.797
HRAS Harvey rat sarcoma viral oncogene homolog 1.794
NF2 neurofibromin 2 (merlin) 1.792
BAIAP2L1 BAI1-associated protein 2-like 1 1.788
WDR72 WD repeat domain 72 1.788
CLTC clathrin, heavy chain (Hc) 1.787
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.783
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.781
CALML5 calmodulin-like 5 1.781
CALML3 calmodulin-like 3 1.777
CALML6 calmodulin-like 6 1.776
CALML4 calmodulin-like 4 1.776
FYN FYN proto-oncogene, Src family tyrosine kinase 1.776
TJP1 tight junction protein 1 1.775
MMP25 matrix metallopeptidase 25 1.773
SYK spleen tyrosine kinase 1.771
EPB41 erythrocyte membrane protein band 4.1 1.764
RAB4A RAB4A, member RAS oncogene family 1.763
ANKFY1 ankyrin repeat and FYVE domain containing 1 1.756
MTSS1 metastasis suppressor 1 1.756
INPP5K inositol polyphosphate-5-phosphatase K 1.754
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.754
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.752
SYNJ2 synaptojanin 2 1.746
ITGB1BP1 integrin beta 1 binding protein 1 1.741
ARHGAP24 Rho GTPase activating protein 24 1.738
TGFB1 transforming growth factor, beta 1 1.738
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 1.738
RRAS related RAS viral (r-ras) oncogene homolog 1.737
ILK integrin-linked kinase 1.735
CTBP1 C-terminal binding protein 1 1.733
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.731
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 1.731
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.729
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.729
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.727
NCKAP1L NCK-associated protein 1-like 1.724
ARF5 ADP-ribosylation factor 5 1.723
PTEN phosphatase and tensin homolog 1.722
AMTN amelotin 1.718
SNX5 sorting nexin 5 1.717
ELMO1 engulfment and cell motility 1 1.717
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.717
LIMA1 LIM domain and actin binding 1 1.708
JUN jun proto-oncogene 1.705
TFRC transferrin receptor 1.705
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 1.701
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 1.7
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.7
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 1.7
ARF3 ADP-ribosylation factor 3 1.699
NCKAP1 NCK-associated protein 1 1.697
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.689
DNAH8 dynein, axonemal, heavy chain 8 1.685
PIKFYVE phosphoinositide kinase, FYVE finger containing 1.685
ACTN1 actinin, alpha 1 1.684
SYNJ1 synaptojanin 1 1.684
TNF tumor necrosis factor 1.683
TIAM2 T-cell lymphoma invasion and metastasis 2 1.683
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.678
CYFIP1 cytoplasmic FMR1 interacting protein 1 1.676
EPS15 epidermal growth factor receptor pathway substrate 15 1.674
STARD13 StAR-related lipid transfer (START) domain containing 13 1.673
ICAM1 intercellular adhesion molecule 1 1.67
FNBP1L formin binding protein 1-like 1.666
CDH5 cadherin 5, type 2 (vascular endothelium) 1.663
USP6NL USP6 N-terminal like 1.662
MTMR6 myotubularin related protein 6 1.659
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.657
FNBP1 formin binding protein 1 1.657
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.657
IL1B interleukin 1, beta 1.656
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 1.656
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 1.654
CD2AP CD2-associated protein 1.652
ITSN1 intersectin 1 (SH3 domain protein) 1.648
DOCK2 dedicator of cytokinesis 2 1.641
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 1.639
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 1.637
MMP9 matrix metallopeptidase 9 1.633
SSH1 slingshot protein phosphatase 1 1.633
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 1.631
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 1.631
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.631
DOCK10 dedicator of cytokinesis 10 1.63
TP53 tumor protein p53 1.63
SLTM SAFB-like, transcription modulator 1.629
CTNND1 catenin (cadherin-associated protein), delta 1 1.627
VTN vitronectin 1.626
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.624
NGF nerve growth factor (beta polypeptide) 1.619
BTK Bruton agammaglobulinemia tyrosine kinase 1.609
MICALL2 MICAL-like 2 1.606
RAP2B RAP2B, member of RAS oncogene family 1.603
MARCKS myristoylated alanine-rich protein kinase C substrate 1.602
IQSEC1 IQ motif and Sec7 domain 1 1.6
CORO1A coronin, actin binding protein, 1A 1.598
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.594
RHOQ ras homolog family member Q 1.593
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.593
CXCL12 chemokine (C-X-C motif) ligand 12 1.59
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1.58
CCM2 cerebral cavernous malformation 2 1.58
CSK c-src tyrosine kinase 1.577
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.576
PI3 peptidase inhibitor 3, skin-derived 1.567
SH3PXD2B SH3 and PX domains 2B 1.558
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.556
CORO7-PAM16 CORO7-PAM16 readthrough 1.555
ARHGAP22 Rho GTPase activating protein 22 1.554
ARFIP2 ADP-ribosylation factor interacting protein 2 1.553
TLR4 toll-like receptor 4 1.552
EPHA2 EPH receptor A2 1.551
BAIAP2L2 BAI1-associated protein 2-like 2 1.551
RALGDS ral guanine nucleotide dissociation stimulator 1.55
RAB13 RAB13, member RAS oncogene family 1.549
CD4 CD4 molecule 1.548
NRG1 neuregulin 1 1.544
ABI2 abl-interactor 2 1.543
ESR1 estrogen receptor 1 1.542
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.539
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.538
RHOH ras homolog family member H 1.538
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 1.536
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.533
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.531
CXCR4 chemokine (C-X-C motif) receptor 4 1.53
SNX1 sorting nexin 1 1.53
DNM1 dynamin 1 1.53
MYO1B myosin IB 1.529
EPS8L3 EPS8-like 3 1.526
SH3KBP1 SH3-domain kinase binding protein 1 1.525
ECT2 epithelial cell transforming 2 1.52
CHN1 chimerin 1 1.519
PRKCA protein kinase C, alpha 1.516
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39 1.515
IGF1 insulin-like growth factor 1 (somatomedin C) 1.512
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.512
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.511
IL6 interleukin 6 1.511
MAP2K1 mitogen-activated protein kinase kinase 1 1.508
NOD1 nucleotide-binding oligomerization domain containing 1 1.508
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.508
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 1.507
RNASE3 ribonuclease, RNase A family, 3 1.507
ERBB3 erb-b2 receptor tyrosine kinase 3 1.505
IFNG interferon, gamma 1.504
FMNL3 formin-like 3 1.504
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 1.503
FGD1 FYVE, RhoGEF and PH domain containing 1 1.503
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 1.502
CYTH4 cytohesin 4 1.501
NCK2 NCK adaptor protein 2 1.499
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.498
CCND1 cyclin D1 1.498
LCK LCK proto-oncogene, Src family tyrosine kinase 1.497
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.497
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.496
FHOD1 formin homology 2 domain containing 1 1.493
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.493
SPATA13 spermatogenesis associated 13 1.492
DOCK9 dedicator of cytokinesis 9 1.49
TRIP10 thyroid hormone receptor interactor 10 1.489
SPRY2 sprouty homolog 2 (Drosophila) 1.487
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.485
SH3YL1 SH3 and SYLF domain containing 1 1.485
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.484
DIAPH1 diaphanous-related formin 1 1.483
LAYN layilin 1.481
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.48
ITSN2 intersectin 2 1.474
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.469
FLOT1 flotillin 1 1.467
CORO1C coronin, actin binding protein, 1C 1.467
MYO9B myosin IXB 1.466
CALD1 caldesmon 1 1.464
NOD2 nucleotide-binding oligomerization domain containing 2 1.464
IQGAP2 IQ motif containing GTPase activating protein 2 1.462
ARHGAP17 Rho GTPase activating protein 17 1.46
INSR insulin receptor 1.458
RHOF ras homolog family member F (in filopodia) 1.458
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.458
CCL2 chemokine (C-C motif) ligand 2 1.456
PSD4 pleckstrin and Sec7 domain containing 4 1.452
ODAPH odontogenesis associated phosphoprotein 1.448
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.445
EFNA1 ephrin-A1 1.445
MMP2 matrix metallopeptidase 2 1.442
ANXA2 annexin A2 1.442
EPN3 epsin 3 1.44
CXCL8 chemokine (C-X-C motif) ligand 8 1.44
EPN2 epsin 2 1.437
FMNL1 formin-like 1 1.437
ODAM odontogenic, ameloblast asssociated 1.436
JMY junction mediating and regulatory protein, p53 cofactor 1.436
NCF1 neutrophil cytosolic factor 1 1.436
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.435
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.434
DGKA diacylglycerol kinase, alpha 80kDa 1.429
CYBB cytochrome b-245, beta polypeptide 1.427
SNX33 sorting nexin 33 1.426
GSK3B glycogen synthase kinase 3 beta 1.426
EXOC2 exocyst complex component 2 1.426
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.426
EVL Enah/Vasp-like 1.423
CYRIB CYFIP related Rac1 interactor B 1.422
RAB10 RAB10, member RAS oncogene family 1.42
ACTG1 actin gamma 1 1.419
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.417
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.417
RAB35 RAB35, member RAS oncogene family 1.417
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 1.416
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.415
ADAP1 ArfGAP with dual PH domains 1 1.414
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.413
ARHGAP26 Rho GTPase activating protein 26 1.411
DLC1 DLC1 Rho GTPase activating protein 1.411
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.411
EPS8L1 EPS8-like 1 1.41
CD8A CD8a molecule 1.409
SNAI1 snail family zinc finger 1 1.409
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.409
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.407
KRIT1 KRIT1, ankyrin repeat containing 1.403
SNX18 sorting nexin 18 1.402
MYO5A myosin VA (heavy chain 12, myoxin) 1.401
BCAR3 breast cancer anti-estrogen resistance 3 1.394
RHOU ras homolog family member U 1.393
RND3 Rho family GTPase 3 1.389
MYH9 myosin, heavy chain 9, non-muscle 1.389
MTSS2 MTSS I-BAR domain containing 2 1.389
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.388
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.388
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.387
CTSK cathepsin K 1.386
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.386
ARF4 ADP-ribosylation factor 4 1.386
DBNL drebrin-like 1.385
PRKCZ protein kinase C, zeta 1.385
RAB20 RAB20, member RAS oncogene family 1.382
MTMR2 myotubularin related protein 2 1.382
RHOJ ras homolog family member J 1.381
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.38
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.379
MYO1A myosin IA 1.376
PRKD1 protein kinase D1 1.372
AXL AXL receptor tyrosine kinase 1.37
LGALS3 lectin, galactoside-binding, soluble, 3 1.37
ARHGAP44 Rho GTPase activating protein 44 1.369
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 1.368
CD63 CD63 molecule 1.367
RIN1 Ras and Rab interactor 1 1.364
LPP LIM domain containing preferred translocation partner in lipoma 1.361
PELP1 proline, glutamate and leucine rich protein 1 1.36
ARRB1 arrestin, beta 1 1.359
DOCK5 dedicator of cytokinesis 5 1.358
FGD2 FYVE, RhoGEF and PH domain containing 2 1.358
PTPRC protein tyrosine phosphatase, receptor type, C 1.357
MYO5B myosin VB 1.357
FGF7 fibroblast growth factor 7 1.356
CCL19 chemokine (C-C motif) ligand 19 1.354
SNAI2 snail family zinc finger 2 1.354
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.354
SNAP91 synaptosomal-associated protein, 91kDa 1.353
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.353
AMELX amelogenin, X-linked 1.352
RHOBTB1 Rho-related BTB domain containing 1 1.352
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 1.35
KDR kinase insert domain receptor 1.35
MAPK1 mitogen-activated protein kinase 1 1.349
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 1.348
LGALS4 lectin, galactoside-binding, soluble, 4 1.346
ICAM2 intercellular adhesion molecule 2 1.345
CSF1R colony stimulating factor 1 receptor 1.344
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.342
TMOD4 tropomodulin 4 (muscle) 1.342
IL4 interleukin 4 1.341
STIM1 stromal interaction molecule 1 1.338
ERVW-1 endogenous retrovirus group W, member 1 1.338
ITGAV integrin, alpha V 1.335
SORBS3 sorbin and SH3 domain containing 3 1.333
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.332
MTM1 myotubularin 1 1.329
CLIP1 CAP-GLY domain containing linker protein 1 1.329
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 1.326
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.325
LIMS1 LIM and senescent cell antigen-like domains 1 1.323
RIC8A RIC8 guanine nucleotide exchange factor A 1.322
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.322
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.321
DGKZ diacylglycerol kinase, zeta 1.321
EXOC7 exocyst complex component 7 1.318
CA2 carbonic anhydrase II 1.318
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.317
RAP1A RAP1A, member of RAS oncogene family 1.317
ANXA5 annexin A5 1.315
CD47 CD47 molecule 1.315
FGF10 fibroblast growth factor 10 1.314
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 1.314
ARHGAP5 Rho GTPase activating protein 5 1.313
ARRB2 arrestin, beta 2 1.311
NCF2 neutrophil cytosolic factor 2 1.311
KALRN kalirin, RhoGEF kinase 1.31
MYO1E myosin IE 1.309
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.308
HDAC6 histone deacetylase 6 1.306
DOCK7 dedicator of cytokinesis 7 1.304
STK10 serine/threonine kinase 10 1.304
COBL cordon-bleu WH2 repeat protein 1.304
IL10 interleukin 10 1.303
CARMIL1 capping protein regulator and myosin 1 linker 1 1.303
GAS6 growth arrest-specific 6 1.302
RACK1 receptor for activated C kinase 1 1.302
PLS3 plastin 3 1.301
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 1.299
RHOV ras homolog family member V 1.298
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.297
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.296
PDPN podoplanin 1.292
SPHK1 sphingosine kinase 1 1.292
DOCK4 dedicator of cytokinesis 4 1.292
IGF1R insulin-like growth factor 1 receptor 1.292
SOS2 son of sevenless homolog 2 (Drosophila) 1.291
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.291
SKAP2 src kinase associated phosphoprotein 2 1.29
MYO18A myosin XVIIIA 1.29
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.289
VCAM1 vascular cell adhesion molecule 1 1.288
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.288
IL2 interleukin 2 1.288
LIMK2 LIM domain kinase 2 1.286
DAAM1 dishevelled associated activator of morphogenesis 1 1.284
FGF9 fibroblast growth factor 9 1.284
PTS 6-pyruvoyltetrahydropterin synthase 1.282
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 1.281
FGF18 fibroblast growth factor 18 1.281
CLEC7A C-type lectin domain family 7, member A 1.28
CCR7 chemokine (C-C motif) receptor 7 1.28
TNK2 tyrosine kinase, non-receptor, 2 1.279
BCR breakpoint cluster region 1.278
BCL2 B-cell CLL/lymphoma 2 1.276
SCIMP SLP adaptor and CSK interacting membrane protein 1.276
TRAF4 TNF receptor-associated factor 4 1.274
ACP5 acid phosphatase 5, tartrate resistant 1.274
SCARB1 scavenger receptor class B, member 1 1.273
FGF4 fibroblast growth factor 4 1.272
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.271
FGF5 fibroblast growth factor 5 1.271
TLR2 toll-like receptor 2 1.271
FGF17 fibroblast growth factor 17 1.27
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.27
MPZ myelin protein zero 1.269
SLC4A2 solute carrier family 4 (anion exchanger), member 2 1.268
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.266
PECAM1 platelet/endothelial cell adhesion molecule 1 1.265
FGF8 fibroblast growth factor 8 (androgen-induced) 1.264
FGF22 fibroblast growth factor 22 1.264
FGF6 fibroblast growth factor 6 1.263
CAVIN1 caveolae associated protein 1 1.263
FGF16 fibroblast growth factor 16 1.262
INPP5J inositol polyphosphate-5-phosphatase J 1.262
FGF3 fibroblast growth factor 3 1.262
MYO1F myosin IF 1.261
SCARB2 scavenger receptor class B, member 2 1.261
CLCN7 chloride channel, voltage-sensitive 7 1.26
ELMO2 engulfment and cell motility 2 1.26
FGF20 fibroblast growth factor 20 1.26
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.259
DBN1 drebrin 1 1.258
ERBB4 erb-b2 receptor tyrosine kinase 4 1.258
RALB v-ral simian leukemia viral oncogene homolog B 1.256
ZEB1 zinc finger E-box binding homeobox 1 1.255
ERV3-1 endogenous retrovirus group 3, member 1 1.254
FGD4 FYVE, RhoGEF and PH domain containing 4 1.254
MAPK8 mitogen-activated protein kinase 8 1.253
CD36 CD36 molecule (thrombospondin receptor) 1.253
FOS FBJ murine osteosarcoma viral oncogene homolog 1.252
HIP1R huntingtin interacting protein 1 related 1.252
KLHL41 kelch-like family member 41 1.251
ANXA1 annexin A1 1.251
CLASP2 cytoplasmic linker associated protein 2 1.251
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 1.251
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.251
MTMR9 myotubularin related protein 9 1.25
SLK STE20-like kinase 1.249
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.249
FMNL2 formin-like 2 1.249
EPS8L2 EPS8-like 2 1.248
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.246
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 1.245
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.245
FLOT2 flotillin 2 1.243
CYRIA CYFIP related Rac1 interactor A 1.243
AFDN afadin, adherens junction formation factor 1.243
TGFB1I1 transforming growth factor beta 1 induced transcript 1 1.238
MYO5C myosin VC 1.238
AIF1 allograft inflammatory factor 1 1.237
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.236
MYO10 myosin X 1.235
DOCK3 dedicator of cytokinesis 3 1.235
ADD1 adducin 1 (alpha) 1.235
MYH10 myosin, heavy chain 10, non-muscle 1.234
CD9 CD9 molecule 1.233
GPR68 G protein-coupled receptor 68 1.232
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.232
NOX1 NADPH oxidase 1 1.232
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.23
HCK HCK proto-oncogene, Src family tyrosine kinase 1.23
MTMR4 myotubularin related protein 4 1.23
ABHD12B abhydrolase domain containing 12B 1.229
TMSB4X thymosin beta 4, X-linked 1.227
CCL21 chemokine (C-C motif) ligand 21 1.226
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.226
SDC4 syndecan 4 1.226
DGKG diacylglycerol kinase, gamma 90kDa 1.224
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 1.224
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.223
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.223
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.223
OCLN occludin 1.222
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.22
ACTA1 actin, alpha 1, skeletal muscle 1.217
S1PR3 sphingosine-1-phosphate receptor 3 1.217
GIPC1 GIPC PDZ domain containing family, member 1 1.217
LLGL1 lethal giant larvae homolog 1 (Drosophila) 1.216
SELPLG selectin P ligand 1.216
KNG1 kininogen 1 1.215
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B 1.215
MYO6 myosin VI 1.213
SACK1H scaffolding CK1 anchoring protein H 1.212
DIAPH2 diaphanous-related formin 2 1.211
MYLK3 myosin light chain kinase 3 1.21
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.21
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.209
PRKD3 protein kinase D3 1.208
STX4 syntaxin 4 1.208
THBS1 thrombospondin 1 1.208
PRKD2 protein kinase D2 1.207
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.206
AMOT angiomotin 1.206
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.205
RAB6A RAB6A, member RAS oncogene family 1.204
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 1.204
FERMT3 fermitin family member 3 1.202
LAMP2 lysosomal-associated membrane protein 2 1.202
RAP1B RAP1B, member of RAS oncogene family 1.201
SVIL supervillin 1.2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 1.2
RND1 Rho family GTPase 1 1.199
RCC1 regulator of chromosome condensation 1 1.199
SELL selectin L 1.198
FYB1 FYN binding protein 1 1.197
ADD3 adducin 3 (gamma) 1.196
SKAP1 src kinase associated phosphoprotein 1 1.195
EPHA1 EPH receptor A1 1.194
IL18 interleukin 18 1.194
TGFA transforming growth factor, alpha 1.194
ADD2 adducin 2 (beta) 1.194
EXOC4 exocyst complex component 4 1.193
GOLGA2 golgin A2 1.193
PTP4A3 protein tyrosine phosphatase type IVA, member 3 1.193
CD86 CD86 molecule 1.192
NF1 neurofibromin 1 1.19
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.189
VAMP3 vesicle-associated membrane protein 3 1.188
UTRN utrophin 1.186
STK26 serine/threonine protein kinase 26 1.185
RAB5C RAB5C, member RAS oncogene family 1.184
HSPB1 heat shock 27kDa protein 1 1.184
PODXL podocalyxin-like 1.184
OR5H6 olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene) 1.183
SDC1 syndecan 1 1.182
IL1A interleukin 1, alpha 1.181
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.179
STK24 serine/threonine kinase 24 1.179
ARL4A ADP-ribosylation factor-like 4A 1.178
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.178
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.177
EFNB2 ephrin-B2 1.175
LIMD1 LIM domains containing 1 1.175
FSCN3 fascin actin-bundling protein 3, testicular 1.175
MACF1 microtubule-actin crosslinking factor 1 1.174
PLAU plasminogen activator, urokinase 1.173
CORO1B coronin, actin binding protein, 1B 1.173
PRKCSH protein kinase C substrate 80K-H 1.172
KSR1 kinase suppressor of ras 1 1.169
BECN1 beclin 1, autophagy related 1.167
PARVA parvin, alpha 1.166
RND2 Rho family GTPase 2 1.162
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.162
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.16
MAPK11 mitogen-activated protein kinase 11 1.159
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.158
HSPB2 heat shock 27kDa protein 2 1.158
EFNA2 ephrin-A2 1.157
RAB7A RAB7A, member RAS oncogene family 1.156
STMN1 stathmin 1 1.156
GLB1 galactosidase, beta 1 1.155
SH3GL1 SH3-domain GRB2-like 1 1.155
EHD1 EH-domain containing 1 1.155
CLDN1 claudin 1 1.153
NCF4 neutrophil cytosolic factor 4, 40kDa 1.152
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.151
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.149
EFNB1 ephrin-B1 1.146
AKAP11 A kinase (PRKA) anchor protein 11 1.145
LGALS8 lectin, galactoside-binding, soluble, 8 1.145
PLAUR plasminogen activator, urokinase receptor 1.145
NOX4 NADPH oxidase 4 1.144
SPIRE1 spire-type actin nucleation factor 1 1.143
FES FES proto-oncogene, tyrosine kinase 1.142
PGR progesterone receptor 1.14
PARVB parvin, beta 1.138
VIPR1 vasoactive intestinal peptide receptor 1 1.137
AKAP13 A kinase (PRKA) anchor protein 13 1.137
RAB31 RAB31, member RAS oncogene family 1.137
PHGDH phosphoglycerate dehydrogenase 1.135
HSPB3 heat shock 27kDa protein 3 1.132
MAPK14 mitogen-activated protein kinase 14 1.132
MYD88 myeloid differentiation primary response 88 1.13
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.129
DENND1C DENN/MADD domain containing 1C 1.128
SPIRE2 spire-type actin nucleation factor 2 1.127
IL3 interleukin 3 1.127
RCC2 regulator of chromosome condensation 2 1.126
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 1.126
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.125
PVR poliovirus receptor 1.124
ENAH enabled homolog (Drosophila) 1.121
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 1.12
CD151 CD151 molecule (Raph blood group) 1.12
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.12
PLA2G4F phospholipase A2, group IVF 1.119
TCHP trichoplein, keratin filament binding 1.119
GRHL3 grainyhead-like 3 (Drosophila) 1.119
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.118
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 1.117
IFNB1 interferon, beta 1, fibroblast 1.117
RHEB Ras homolog enriched in brain 1.116
CLDN7 claudin 7 1.115
CD81 CD81 molecule 1.113
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 1.112
BMX BMX non-receptor tyrosine kinase 1.112
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.112
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.111
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.11
ACTN3 actinin, alpha 3 (gene/pseudogene) 1.109
AGFG1 ArfGAP with FG repeats 1 1.106
EXOC8 exocyst complex component 8 1.105
CXXC1 CXXC finger protein 1 1.104
TYROBP TYRO protein tyrosine kinase binding protein 1.104
APOE apolipoprotein E 1.103
CASR calcium-sensing receptor 1.103
RAB7B RAB7B, member RAS oncogene family 1.102
SNAP23 synaptosomal-associated protein, 23kDa 1.102
POTEF POTE ankyrin domain family, member F 1.101
ARHGAP25 Rho GTPase activating protein 25 1.1
SPRR1A small proline-rich protein 1A 1.098
CYBA cytochrome b-245, alpha polypeptide 1.097
CDK4 cyclin-dependent kinase 4 1.097
TGOLN2 trans-golgi network protein 2 1.096
WDR1 WD repeat domain 1 1.095
CDK5 cyclin-dependent kinase 5 1.093
NECTIN1 nectin cell adhesion molecule 1 1.093
PIEZO1 piezo-type mechanosensitive ion channel component 1 1.092
PKN1 protein kinase N1 1.09
RAB27A RAB27A, member RAS oncogene family 1.088
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.088
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.082
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.082
NTN1 netrin 1 1.081
EFNA4 ephrin-A4 1.081
ACTN2 actinin, alpha 2 1.08
NLRC4 NLR family, CARD domain containing 4 1.079
APP amyloid beta (A4) precursor protein 1.077
CD68 CD68 molecule 1.077
EXOC5 exocyst complex component 5 1.075
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.075
SHH sonic hedgehog 1.074
MAP2K3 mitogen-activated protein kinase kinase 3 1.073
BDNF brain-derived neurotrophic factor 1.073
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.073
RIGI RNA sensor RIG-I 1.072
RAB40B RAB40B, member RAS oncogene family 1.069
CLINT1 clathrin interactor 1 1.067
OSTM1 osteopetrosis associated transmembrane protein 1 1.067
CTSS cathepsin S 1.067
PALD1 phosphatase domain containing, paladin 1 1.067
PLEC plectin 1.066
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.065
RAB14 RAB14, member RAS oncogene family 1.065
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.065
WASHC2C WASH complex subunit 2C 1.065
SPHK2 sphingosine kinase 2 1.064
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.063
ELMO3 engulfment and cell motility 3 1.063
SEPTIN2 septin 2 1.063
HSPA4 heat shock 70kDa protein 4 1.062
CALCOCO2 calcium binding and coiled-coil domain 2 1.06
RAB5B RAB5B, member RAS oncogene family 1.06
GAS7 growth arrest-specific 7 1.059
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 1.059
CNRIP1 cannabinoid receptor interacting protein 1 1.058
LMNA lamin A/C 1.058
F11R F11 receptor 1.058
OR52A5 olfactory receptor, family 52, subfamily A, member 5 1.056
RAB25 RAB25, member RAS oncogene family 1.055
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.055
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 1.053
BCL2L1 BCL2-like 1 1.053
CD80 CD80 molecule 1.053
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.053
ADRB2 adrenoceptor beta 2, surface 1.053
RAB22A RAB22A, member RAS oncogene family 1.052
FMN1 formin 1 1.052
DOCK6 dedicator of cytokinesis 6 1.052
ARL4C ADP-ribosylation factor-like 4C 1.051
NUMB numb homolog (Drosophila) 1.051
NEB nebulin 1.051
ORAI1 ORAI calcium release-activated calcium modulator 1 1.05
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 1.05
EXOC3 exocyst complex component 3 1.049
EFNB3 ephrin-B3 1.049
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.048
CD19 CD19 molecule 1.048
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.048
CDKN2A cyclin-dependent kinase inhibitor 2A 1.048
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 1.046
AHNAK AHNAK nucleoprotein 1.045
SIRPA signal-regulatory protein alpha 1.044
AJUBA ajuba LIM protein 1.04
CAPN2 calpain 2, (m/II) large subunit 1.039
EHD3 EH-domain containing 3 1.038
ATG5 autophagy related 5 1.038
NOX3 NADPH oxidase 3 1.037
EHD2 EH-domain containing 2 1.037
CYCS cytochrome c, somatic 1.037
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.036
CD28 CD28 molecule 1.035
CTSD cathepsin D 1.035
EPHB2 EPH receptor B2 1.035
SORBS2 sorbin and SH3 domain containing 2 1.034
NHLRC2 NHL repeat containing 2 1.033
SEPTIN6 septin 6 1.032
S100A10 S100 calcium binding protein A10 1.031
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.03
PPP1R9B protein phosphatase 1, regulatory subunit 9B 1.03
C3 complement component 3 1.03
RICTOR RPTOR independent companion of MTOR, complex 2 1.029
WTIP Wilms tumor 1 interacting protein 1.029
H3-5 H3.5 histone 1.029
BUB1B-PAK6 BUB1B-PAK6 readthrough 1.029
H3-7 H3.7 histone (putative) 1.029
H3C13 H3 clustered histone 13 1.029
RAB1A RAB1A, member RAS oncogene family 1.028
H3-4 H3.4 histone, cluster member 1.028
FGR FGR proto-oncogene, Src family tyrosine kinase 1.027
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 1.026
GTPBP4 GTP binding protein 4 1.025
CDK1 cyclin-dependent kinase 1 1.025
H3-3B H3.3 histone B 1.025
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.024
EXOC1 exocyst complex component 1 1.024
S100A4 S100 calcium binding protein A4 1.024
EFNA3 ephrin-A3 1.024
AGXT alanine-glyoxylate aminotransferase 1.022
PSD2 pleckstrin and Sec7 domain containing 2 1.022
TSC2 tuberous sclerosis 2 1.022
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1.022
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.021
MRC1 mannose receptor, C type 1 1.021
PARD6A par-6 family cell polarity regulator alpha 1.021
H3C7 H3 clustered histone 7 1.02
ARL11 ADP-ribosylation factor-like 11 1.019
PHACTR3 phosphatase and actin regulator 3 1.018
SEPTIN9 septin 9 1.016
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.015
EPN1 epsin 1 1.015
TBC1D2 TBC1 domain family, member 2 1.015
EFNA5 ephrin-A5 1.014
OPTN optineurin 1.013
GAB2 GRB2-associated binding protein 2 1.013
FGD5 FYVE, RhoGEF and PH domain containing 5 1.013
MAPK12 mitogen-activated protein kinase 12 1.012
HBEGF heparin-binding EGF-like growth factor 1.012
BSG basigin (Ok blood group) 1.012
ARHGAP10 Rho GTPase activating protein 10 1.012
PRKG1 protein kinase, cGMP-dependent, type I 1.011
MAPK13 mitogen-activated protein kinase 13 1.011
CD40 CD40 molecule, TNF receptor superfamily member 5 1.011
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.009
RACGAP1 Rac GTPase activating protein 1 1.009
CD2 CD2 molecule 1.009
GSDMD gasdermin D 1.008
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.008
RIPOR1 RHO family interacting cell polarization regulator 1 1.007
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.006
PROM1 prominin 1 1.006
KRT18 keratin 18, type I 1.005
SACK1G scaffolding CK1 anchoring protein G 1.004
NOXA1 NADPH oxidase activator 1 1.004
TMOD1 tropomodulin 1 1.004
FPR1 formyl peptide receptor 1 1.003
CANX calnexin 1.002
PTGES2 prostaglandin E synthase 2 1.001
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.0
GAP43 growth associated protein 43 1.0
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.999
NISCH nischarin 0.999
FGFR2 fibroblast growth factor receptor 2 0.999
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.997
CLDN4 claudin 4 0.997
SELENOP selenoprotein P 0.997
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.996
LUZP1 leucine zipper protein 1 0.995
PTK6 protein tyrosine kinase 6 0.995
ARHGAP31 Rho GTPase activating protein 31 0.995
NRP1 neuropilin 1 0.993
AIF1L allograft inflammatory factor 1-like 0.993
SEPTIN7 septin 7 0.993
RAB40A RAB40A, member RAS oncogene family 0.991
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.99
IRS1 insulin receptor substrate 1 0.99
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.989
LDLR low density lipoprotein receptor 0.989
VAMP8 vesicle-associated membrane protein 8 0.989
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 0.988
TBC1D4 TBC1 domain family, member 4 0.988
SELE selectin E 0.988
CTSA cathepsin A 0.987
CTRL chymotrypsin-like 0.987
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.986
S1PR2 sphingosine-1-phosphate receptor 2 0.986
PPME1 protein phosphatase methylesterase 1 0.986
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.985
LY96 lymphocyte antigen 96 0.984
KRT8 keratin 8, type II 0.984
TLR3 toll-like receptor 3 0.984
SLIT3 slit homolog 3 (Drosophila) 0.983
WNT5A wingless-type MMTV integration site family, member 5A 0.982
IL17F interleukin 17F 0.981
KITLG KIT ligand 0.981
TOX4 TOX high mobility group box family member 4 0.981
DCSTAMP dendrocyte expressed seven transmembrane protein 0.98
GRAP2 GRB2-related adaptor protein 2 0.979
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.979
CLTA clathrin, light chain A 0.979
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.979
MAPK7 mitogen-activated protein kinase 7 0.979
EHBP1 EH domain binding protein 1 0.978
MAP3K10 mitogen-activated protein kinase kinase kinase 10 0.977
NES nestin 0.977
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.977
OPHN1 oligophrenin 1 0.976
IRF3 interferon regulatory factor 3 0.976
SLIT2 slit homolog 2 (Drosophila) 0.974
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.974
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 0.973
TRIP6 thyroid hormone receptor interactor 6 0.973
SMAD4 SMAD family member 4 0.973
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 0.972
DLG1 discs, large homolog 1 (Drosophila) 0.972
SQSTM1 sequestosome 1 0.971
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.97
SCAMP3 secretory carrier membrane protein 3 0.97
CIB1 calcium and integrin binding 1 (calmyrin) 0.969
RASIP1 Ras interacting protein 1 0.969
GRB7 growth factor receptor-bound protein 7 0.969
CAV2 caveolin 2 0.968
GFAP glial fibrillary acidic protein 0.968
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.967
LMTK2 lemur tyrosine kinase 2 0.967
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 0.967
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.967
FIG4 FIG4 phosphoinositide 5-phosphatase 0.967
DNMBP dynamin binding protein 0.967
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.967
ULK1 unc-51 like autophagy activating kinase 1 0.966
CAV3 caveolin 3 0.966
CCL3 chemokine (C-C motif) ligand 3 0.966
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.965
TOM1 target of myb1 (chicken) 0.965
FGF13 fibroblast growth factor 13 0.964
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 0.964
EPCAM epithelial cell adhesion molecule 0.963
MMP7 matrix metallopeptidase 7 0.963
MMP1 matrix metallopeptidase 1 0.963
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.963
MAP1B microtubule-associated protein 1B 0.962
ABLIM1 actin binding LIM protein 1 0.962
ARHGAP29 Rho GTPase activating protein 29 0.962
SOX2 SRY (sex determining region Y)-box 2 0.962
LOX lysyl oxidase 0.962
SCRIB scribbled planar cell polarity protein 0.961
AGRN agrin 0.961
TWF2 twinfilin actin binding protein 2 0.96
TYRO3 TYRO3 protein tyrosine kinase 0.96
CSRP1 cysteine and glycine-rich protein 1 0.96
DVL1 dishevelled segment polarity protein 1 0.96
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.959
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.958
CDC50B cell division cycle 50 P4-ATPase accessory subunit B 0.957
RIPK2 receptor-interacting serine-threonine kinase 2 0.956
STAT5B signal transducer and activator of transcription 5B 0.956
EPHB4 EPH receptor B4 0.956
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.956
S100A8 S100 calcium binding protein A8 0.955
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.955
SYNPO synaptopodin 0.954
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.952
SLC25A40 solute carrier family 25, member 40 0.951
SH3GL2 SH3-domain GRB2-like 2 0.95
TMEM229A transmembrane protein 229A 0.95
CALCR calcitonin receptor 0.95
PI4K2B phosphatidylinositol 4-kinase type 2 beta 0.95
TLR9 toll-like receptor 9 0.95
ITGB4 integrin, beta 4 0.949
NAV2 neuron navigator 2 0.949
NUMBL numb homolog (Drosophila)-like 0.948
PLXNB2 plexin B2 0.948
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.948
C1D C1D nuclear receptor corepressor 0.947
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.947
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.946
MFGE8 milk fat globule-EGF factor 8 protein 0.945
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.945
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.944
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.944
ABI3 ABI family, member 3 0.943
FAM107A family with sequence similarity 107, member A 0.942
TJP2 tight junction protein 2 0.941
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.941
TMOD3 tropomodulin 3 (ubiquitous) 0.941
CTSB cathepsin B 0.94
ARL13B ADP-ribosylation factor-like 13B 0.94
HABP2 hyaluronan binding protein 2 0.939
LMOD2 leiomodin 2 (cardiac) 0.938
FBLIM1 filamin binding LIM protein 1 0.938
LURAP1 leucine rich adaptor protein 1 0.936
PCNA proliferating cell nuclear antigen 0.935
SPNS1 spinster homolog 1 (Drosophila) 0.935
S1PR1 sphingosine-1-phosphate receptor 1 0.935
JAK2 Janus kinase 2 0.933
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.933
PTPRJ protein tyrosine phosphatase, receptor type, J 0.933
NOXO1 NADPH oxidase organizer 1 0.932
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.931
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.93
SNX2 sorting nexin 2 0.93
ATG7 autophagy related 7 0.93
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.929
CD24 CD24 molecule 0.929
PDCD10 programmed cell death 10 0.929
SMAD2 SMAD family member 2 0.928
MYOCD myocardin 0.928
CD209 CD209 molecule 0.926
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.925
NGEF neuronal guanine nucleotide exchange factor 0.925
LRP6 low density lipoprotein receptor-related protein 6 0.924
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.924
SEPTIN11 septin 11 0.924
USP6 ubiquitin specific peptidase 6 0.923
CD59 CD59 molecule, complement regulatory protein 0.922
CD34 CD34 molecule 0.921
TLR5 toll-like receptor 5 0.921
MRAS muscle RAS oncogene homolog 0.919
MTMR3 myotubularin related protein 3 0.919