| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | 0.177384 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.167295 |
| LOXL2 | lysyl oxidase-like 2 | 0.162574 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.125441 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.112349 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0941923 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0920628 |
| COL3A1 | collagen, type III, alpha 1 | 0.083509 |
| PLAT | plasminogen activator, tissue | 0.0834733 |
| FLNB | filamin B, beta | 0.0833791 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0789156 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0774613 |
| CD44 | CD44 molecule (Indian blood group) | 0.0761113 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0713923 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0692636 |
| COL1A2 | collagen, type I, alpha 2 | 0.0679156 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0678779 |
| THBS2 | thrombospondin 2 | 0.0673495 |
| APP | amyloid beta (A4) precursor protein | 0.0662294 |
| NAV1 | neuron navigator 1 | 0.0620411 |
| SEPTIN9 | septin 9 | 0.061575 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0612959 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0611364 |
| DST | dystonin | 0.0601243 |
| COL5A2 | collagen, type V, alpha 2 | 0.0590374 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0589311 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0566958 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0562434 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0560591 |
| AUTS2 | autism susceptibility candidate 2 | 0.0557595 |
| OGA | O-GlcNAcase | 0.0554238 |
| SBF2 | SET binding factor 2 | 0.0552012 |
| GPC6 | glypican 6 | 0.055101 |
| MYOF | myoferlin | 0.0530942 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0520165 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0510221 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.050964 |
| ATP13A3 | ATPase type 13A3 | 0.0483003 |
| RNF213 | ring finger protein 213 | 0.0465431 |
| PLEC | plectin | 0.0453727 |
| DENND5A | DENN/MADD domain containing 5A | 0.0448125 |
| NAV2 | neuron navigator 2 | 0.0441393 |
| FLNA | filamin A, alpha | 0.0435003 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0433116 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0429248 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0427511 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0423215 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.042269 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0419942 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0417226 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0415394 |
| MB21D2 | Mab-21 domain containing 2 | 0.041073 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409463 |
| SPAG9 | sperm associated antigen 9 | 0.0405288 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.040072 |
| AHNAK | AHNAK nucleoprotein | 0.0389759 |
| CTSB | cathepsin B | 0.0384587 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.038384 |
| ANXA2 | annexin A2 | 0.0376886 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0365749 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0363478 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.035949 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0355186 |
| PGK1 | phosphoglycerate kinase 1 | 0.0345018 |
| STC1 | stanniocalcin 1 | 0.0343976 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0333539 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.033122 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0327825 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.032656 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0324323 |
| UBC | ubiquitin C | 0.0321827 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0321733 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0319252 |
| ABI1 | abl-interactor 1 | 0.0316281 |
| XPO1 | exportin 1 | 0.0309534 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.030366 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0298937 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0298332 |
| WTAP | Wilms tumor 1 associated protein | 0.0297013 |
| ADAR | adenosine deaminase, RNA-specific | 0.0297012 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0294937 |
| AFAP1 | actin filament associated protein 1 | 0.0293995 |
| HLA-E | major histocompatibility complex, class I, E | 0.0289739 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0285195 |
| HELZ | helicase with zinc finger | 0.0284096 |
| ACTN4 | actinin, alpha 4 | 0.028401 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0283566 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.028226 |
| FMNL2 | formin-like 2 | 0.0281408 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0278589 |
| SETD5 | SET domain containing 5 | 0.0275493 |
| CLIC4 | chloride intracellular channel 4 | 0.0275182 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0274504 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0273243 |
| TMSB4X | thymosin beta 4, X-linked | 0.0270634 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0269782 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0268108 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.02679 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0267173 |
| TRIM22 | tripartite motif containing 22 | 0.0266184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.0669046 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0653853 |
| POTEF | POTE ankyrin domain family, member F | -0.0508253 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0505985 |
| TMSB10 | thymosin beta 10 | -0.0473242 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0464957 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0418109 |
| SUCNR1 | succinate receptor 1 | -0.0352199 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.034748 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0346567 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0307611 |
| EGFR | epidermal growth factor receptor | -0.0306824 |
| PFN1 | profilin 1 | -0.0304009 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0297101 |
| DCLK2 | doublecortin-like kinase 2 | -0.0294704 |
| LMNA | lamin A/C | -0.0292617 |
| FTL | ferritin, light polypeptide | -0.0285822 |
| MYADM | myeloid-associated differentiation marker | -0.0280401 |
| ACTG1 | actin gamma 1 | -0.0274817 |
| MAP1B | microtubule-associated protein 1B | -0.0264165 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0262976 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0260732 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0254177 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0241437 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0229254 |
| EFNA5 | ephrin-A5 | -0.0228978 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0216252 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0215858 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0199779 |
| INTS6 | integrator complex subunit 6 | -0.0193755 |
| FOSL1 | FOS-like antigen 1 | -0.0189478 |
| FN1 | fibronectin 1 | -0.0188986 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0184467 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0181851 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0179756 |
| PCDH7 | protocadherin 7 | -0.0176187 |
| RND3 | Rho family GTPase 3 | -0.0173092 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0169414 |
| FMN2 | formin 2 | -0.016843 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0165872 |
| MT2A | metallothionein 2A | -0.0165094 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.016134 |
| RPL35A | ribosomal protein L35a | -0.0160863 |
| IL7R | interleukin 7 receptor | -0.0157057 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0156187 |
| CSTB | cystatin B (stefin B) | -0.0156113 |
| EGR1 | early growth response 1 | -0.0154894 |
| ANKRD30B | ankyrin repeat domain 30B | -0.0154319 |
| PKM | pyruvate kinase, muscle | -0.0154126 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.0153556 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0153397 |
| RPL28 | ribosomal protein L28 | -0.0151682 |
| CTSD | cathepsin D | -0.0150365 |
| HM13 | histocompatibility (minor) 13 | -0.0149525 |
| RPS8 | ribosomal protein S8 | -0.0149243 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0137324 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0136886 |
| NAV3 | neuron navigator 3 | -0.0135442 |
| SEPTIN7 | septin 7 | -0.0133362 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.013176 |
| CCND1 | cyclin D1 | -0.012985 |
| RPLP1 | ribosomal protein, large, P1 | -0.012688 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0126635 |
| TBCA | tubulin folding cofactor A | -0.0125736 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0124928 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0123528 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0121731 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0120682 |
| MTDH | metadherin | -0.0120169 |
| SEC61G | Sec61 gamma subunit | -0.0119911 |
| RPL37 | ribosomal protein L37 | -0.0119793 |
| VAT1 | vesicle amine transport 1 | -0.0118285 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0116834 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0114851 |
| RIGI | RNA sensor RIG-I | -0.0114768 |
| NUCB2 | nucleobindin 2 | -0.011396 |
| S100A11 | S100 calcium binding protein A11 | -0.0112932 |
| KRT81 | keratin 81, type II | -0.0112847 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | -0.0112012 |
| COL5A1 | collagen, type V, alpha 1 | -0.0111404 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0111078 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | -0.0110991 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0110631 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0110627 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.0110616 |
| HSPB1 | heat shock 27kDa protein 1 | -0.010939 |
| PLXNA2 | plexin A2 | -0.0108186 |
| GDF15 | growth differentiation factor 15 | -0.0107438 |
| IKBIP | IKBKB interacting protein | -0.0106476 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0105794 |
| RPS6 | ribosomal protein S6 | -0.0105575 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0105395 |
| MBTD1 | mbt domain containing 1 | -0.0105254 |
| POMP | proteasome maturation protein | -0.0103295 |
| RACK1 | receptor for activated C kinase 1 | -0.0103049 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.010238 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0102089 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.010125 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -0.0100997 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0100593 |
