| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.198921 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.194665 |
| VIM | vimentin | 0.134417 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.092984 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0907832 |
| PCBP2 | poly(rC) binding protein 2 | 0.0864069 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0857117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0826151 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0765696 |
| TXNRD1 | thioredoxin reductase 1 | 0.0717805 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0701156 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0629068 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.062379 |
| XPO1 | exportin 1 | 0.0615673 |
| NEK7 | NIMA-related kinase 7 | 0.0558459 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0523739 |
| MGAT4C | MGAT4 family, member C | 0.0520127 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0512036 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0509821 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0500119 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0497154 |
| ATP11A | ATPase, class VI, type 11A | 0.0488976 |
| WDR43 | WD repeat domain 43 | 0.0481325 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0471499 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0462698 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0449055 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0441752 |
| RPL7 | ribosomal protein L7 | 0.0441545 |
| YBX1 | Y box binding protein 1 | 0.0432614 |
| MED13L | mediator complex subunit 13-like | 0.0423415 |
| IPO7 | importin 7 | 0.039534 |
| KIF5B | kinesin family member 5B | 0.0394222 |
| USP34 | ubiquitin specific peptidase 34 | 0.0391827 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0391315 |
| ZNF292 | zinc finger protein 292 | 0.0389837 |
| CCNL1 | cyclin L1 | 0.0384783 |
| OGA | O-GlcNAcase | 0.0384686 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0383848 |
| MATR3 | matrin 3 | 0.0381618 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0379809 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0378565 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0375169 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0371229 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0366708 |
| CLTC | clathrin, heavy chain (Hc) | 0.0363978 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.036343 |
| THOC1 | THO complex 1 | 0.0362481 |
| RBM39 | RNA binding motif protein 39 | 0.0360476 |
| AXIN2 | axin 2 | 0.0354796 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0353363 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0352918 |
| GASK1B | golgi associated kinase 1B | 0.0349588 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0348287 |
| ETNK1 | ethanolamine kinase 1 | 0.0347728 |
| RPL11 | ribosomal protein L11 | 0.0344701 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0341019 |
| EPHA6 | EPH receptor A6 | 0.0340439 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0330785 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0330045 |
| PREPL | prolyl endopeptidase-like | 0.0326788 |
| SPAG9 | sperm associated antigen 9 | 0.0323257 |
| ANXA1 | annexin A1 | 0.0322327 |
| TNPO1 | transportin 1 | 0.0318955 |
| NCKAP1 | NCK-associated protein 1 | 0.0318314 |
| DST | dystonin | 0.0315045 |
| CPOX | coproporphyrinogen oxidase | 0.0308095 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0307351 |
| TPM3 | tropomyosin 3 | 0.0306436 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0304573 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0300352 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296494 |
| VMP1 | vacuole membrane protein 1 | 0.029096 |
| RPL19 | ribosomal protein L19 | 0.0288099 |
| LMO7 | LIM domain 7 | 0.0287488 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0287129 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0285845 |
| TMEM41B | transmembrane protein 41B | 0.0283033 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282842 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0282479 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.028029 |
| RPS12 | ribosomal protein S12 | 0.0280041 |
| RPL3 | ribosomal protein L3 | 0.0279459 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0279022 |
| RACK1 | receptor for activated C kinase 1 | 0.0278539 |
| IL6ST | interleukin 6 signal transducer | 0.0278198 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0277605 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0276662 |
| NUP58 | nucleoporin 58 | 0.0274656 |
| TBK1 | TANK-binding kinase 1 | 0.0273679 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0272496 |
| OXR1 | oxidation resistance 1 | 0.0271805 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0271228 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0269169 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0268612 |
| LDHA | lactate dehydrogenase A | 0.0268166 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0267651 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0266745 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0266252 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0265717 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.026392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.127844 |
| NLGN1 | neuroligin 1 | -0.11419 |
| HMGA2 | high mobility group AT-hook 2 | -0.103054 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0645695 |
| EHBP1 | EH domain binding protein 1 | -0.0592807 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.05642 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0558791 |
| PCDH7 | protocadherin 7 | -0.0538888 |
| TMSB10 | thymosin beta 10 | -0.0467617 |
| RASAL2 | RAS protein activator like 2 | -0.0460842 |
| ACTG1 | actin gamma 1 | -0.045027 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0420274 |
| ZNF804A | zinc finger protein 804A | -0.0415359 |
| INTS6 | integrator complex subunit 6 | -0.0398473 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0371762 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.036998 |
| NABP1 | nucleic acid binding protein 1 | -0.0364711 |
| EGR1 | early growth response 1 | -0.0335948 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0333039 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0327471 |
| FTL | ferritin, light polypeptide | -0.0322636 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0303407 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0301291 |
| CUX1 | cut-like homeobox 1 | -0.0297714 |
| NHSL1 | NHS-like 1 | -0.0297349 |
| SYT1 | synaptotagmin I | -0.0297248 |
| MMP12 | matrix metallopeptidase 12 | -0.0294933 |
| NAV3 | neuron navigator 3 | -0.027911 |
| NEBL | nebulette | -0.0272352 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0260172 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0259869 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0257013 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0256529 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0253487 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0246271 |
| ETV6 | ets variant 6 | -0.0246255 |
| PCDH9 | protocadherin 9 | -0.0244555 |
| CANX | calnexin | -0.0238303 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0237443 |
| AHNAK | AHNAK nucleoprotein | -0.0231666 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0225407 |
| JMJD1C | jumonji domain containing 1C | -0.0222771 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0218529 |
| MKI67 | marker of proliferation Ki-67 | -0.0218479 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0215804 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0215352 |
| SETX | senataxin | -0.0214751 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0211044 |
| EXOC4 | exocyst complex component 4 | -0.0209331 |
| RSU1 | Ras suppressor protein 1 | -0.0207405 |
| DENND5B | DENN/MADD domain containing 5B | -0.0206308 |
| TBCA | tubulin folding cofactor A | -0.0206169 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0205582 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0205077 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0203826 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0198131 |
| LRRC23 | leucine rich repeat containing 23 | -0.0193757 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0193756 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0192088 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0191998 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0191183 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0185779 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0183061 |
| PDGFC | platelet derived growth factor C | -0.0180842 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0175691 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0174488 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0170713 |
| R3HDM2 | R3H domain containing 2 | -0.0169767 |
| KSR2 | kinase suppressor of ras 2 | -0.016913 |
| CCND1 | cyclin D1 | -0.016681 |
| FAM193A | family with sequence similarity 193, member A | -0.016481 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0162514 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0162151 |
| CEP112 | centrosomal protein 112kDa | -0.0161785 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0160323 |
| CAVIN1 | caveolae associated protein 1 | -0.0160094 |
| ADIPOR2 | adiponectin receptor 2 | -0.0159939 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.0159184 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0158731 |
| ZNF609 | zinc finger protein 609 | -0.0156994 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0154694 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.015252 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0152323 |
| BPTF | bromodomain PHD finger transcription factor | -0.0152092 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0150958 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0150155 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0149491 |
| ATG7 | autophagy related 7 | -0.0148737 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0147208 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0146787 |
| PARD3B | par-3 family cell polarity regulator beta | -0.014654 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0146063 |
| MAP1B | microtubule-associated protein 1B | -0.014484 |
| BNC2 | basonuclin 2 | -0.0144719 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0144271 |
| AK1 | adenylate kinase 1 | -0.0143909 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0143803 |
| RPL31 | ribosomal protein L31 | -0.0143555 |
| BCHE | butyrylcholinesterase | -0.0143428 |
| MAP4 | microtubule-associated protein 4 | -0.0143421 |
