| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.223739 |
| SMAD3 | SMAD family member 3 | 0.197631 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.170711 |
| FLNB | filamin B, beta | 0.120943 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.11674 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.108319 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.10413 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.096605 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0965164 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0910037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0888496 |
| SPAG9 | sperm associated antigen 9 | 0.0868284 |
| MCL1 | myeloid cell leukemia 1 | 0.0861148 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0766024 |
| MSN | moesin | 0.0702364 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0691388 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0679037 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0662541 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0661031 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.065808 |
| PLEC | plectin | 0.0647108 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0641645 |
| USP3 | ubiquitin specific peptidase 3 | 0.0617821 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.06013 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0595439 |
| HELZ | helicase with zinc finger | 0.0584558 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0562839 |
| PCBP2 | poly(rC) binding protein 2 | 0.0559401 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0552366 |
| NDRG1 | N-myc downstream regulated 1 | 0.0551215 |
| CMIP | c-Maf inducing protein | 0.0546287 |
| FMNL2 | formin-like 2 | 0.0540859 |
| LOXL2 | lysyl oxidase-like 2 | 0.0518282 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0511203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.051118 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0509744 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0499907 |
| FLNA | filamin A, alpha | 0.048894 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0485856 |
| PGK1 | phosphoglycerate kinase 1 | 0.0476709 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0469509 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0464048 |
| FAM107B | family with sequence similarity 107, member B | 0.0458605 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0457858 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0456343 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0453412 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0438009 |
| NAV2 | neuron navigator 2 | 0.043497 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0430869 |
| MYO10 | myosin X | 0.0429904 |
| PKM | pyruvate kinase, muscle | 0.0425844 |
| NUP58 | nucleoporin 58 | 0.0418118 |
| ACTN4 | actinin, alpha 4 | 0.0412334 |
| SEPTIN9 | septin 9 | 0.0401383 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0397225 |
| ENO1 | enolase 1, (alpha) | 0.0393708 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0392873 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0390885 |
| RTN4 | reticulon 4 | 0.0384341 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0379672 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0372196 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0370994 |
| UBC | ubiquitin C | 0.0353876 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0351655 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0351365 |
| RPL7 | ribosomal protein L7 | 0.0350129 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0349494 |
| OGA | O-GlcNAcase | 0.0349443 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0344836 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0341378 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.034134 |
| PFKP | phosphofructokinase, platelet | 0.0336782 |
| MYOF | myoferlin | 0.0334145 |
| MYO1B | myosin IB | 0.0333945 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0330003 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326657 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0326241 |
| KRT18 | keratin 18, type I | 0.0321566 |
| FA2H | fatty acid 2-hydroxylase | 0.031863 |
| CORO1C | coronin, actin binding protein, 1C | 0.0318515 |
| ZNF292 | zinc finger protein 292 | 0.0315936 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0314938 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0308294 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0307602 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306681 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304672 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0303657 |
| LDHA | lactate dehydrogenase A | 0.0303167 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.030123 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0300362 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0299413 |
| ACLY | ATP citrate lyase | 0.0299221 |
| AUTS2 | autism susceptibility candidate 2 | 0.0298615 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0297015 |
| XPO1 | exportin 1 | 0.029506 |
| YEATS2 | YEATS domain containing 2 | 0.0294513 |
| NBAS | neuroblastoma amplified sequence | 0.0294315 |
| GPC6 | glypican 6 | 0.0294026 |
| SUCO | SUN domain containing ossification factor | 0.0293916 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0291877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.101739 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.100721 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0893377 |
| ACTG1 | actin gamma 1 | -0.0776951 |
| KYNU | kynureninase | -0.0664008 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0609062 |
| OSMR | oncostatin M receptor | -0.0551107 |
| MT2A | metallothionein 2A | -0.0533891 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0529429 |
| TMSB10 | thymosin beta 10 | -0.0507427 |
| EHBP1 | EH domain binding protein 1 | -0.0487454 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0477033 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0474651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.045075 |
| VCL | vinculin | -0.0421361 |
| MT1X | metallothionein 1X | -0.0417149 |
| FTL | ferritin, light polypeptide | -0.0415488 |
| RPS6 | ribosomal protein S6 | -0.0409896 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0399016 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0395627 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0386411 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0379431 |
| NTN4 | netrin 4 | -0.0376447 |
| BPTF | bromodomain PHD finger transcription factor | -0.0369693 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0357637 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0326013 |
| KRT81 | keratin 81, type II | -0.0305971 |
| RPS19 | ribosomal protein S19 | -0.030543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303439 |
| GLIS3 | GLIS family zinc finger 3 | -0.0296181 |
| RSPO3 | R-spondin 3 | -0.0291257 |
| HMGA2 | high mobility group AT-hook 2 | -0.028991 |
| SP100 | SP100 nuclear antigen | -0.0288833 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0285223 |
| RHCG | Rh family, C glycoprotein | -0.0281475 |
| PALLD | palladin, cytoskeletal associated protein | -0.0281107 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.027827 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0275761 |
| STC1 | stanniocalcin 1 | -0.0274841 |
| PMP22 | peripheral myelin protein 22 | -0.0263457 |
| DUSP16 | dual specificity phosphatase 16 | -0.0258697 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0253688 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0239032 |
| BICC1 | BicC family RNA binding protein 1 | -0.0233864 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233602 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0229482 |
| RAI14 | retinoic acid induced 14 | -0.0228816 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0220994 |
| EGR1 | early growth response 1 | -0.0219267 |
| MYO9A | myosin IXA | -0.0216133 |
| NABP1 | nucleic acid binding protein 1 | -0.0211246 |
| TBCA | tubulin folding cofactor A | -0.0210079 |
| RAB31 | RAB31, member RAS oncogene family | -0.0208802 |
| RPL12 | ribosomal protein L12 | -0.0207858 |
| ASTN2 | astrotactin 2 | -0.0206908 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0205021 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0201184 |
| CDKL5 | cyclin-dependent kinase-like 5 | -0.0199537 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0199173 |
| EFNA5 | ephrin-A5 | -0.0192672 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192229 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0190753 |
| HLA-B | major histocompatibility complex, class I, B | -0.0187873 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | -0.0186417 |
| CCDC88A | coiled-coil domain containing 88A | -0.0186343 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0183444 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0181148 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.018011 |
| NRP1 | neuropilin 1 | -0.018 |
| RIGI | RNA sensor RIG-I | -0.0178952 |
| RPL32 | ribosomal protein L32 | -0.0177088 |
| RPS13 | ribosomal protein S13 | -0.0175932 |
| RANBP17 | RAN binding protein 17 | -0.0171734 |
| RPS16 | ribosomal protein S16 | -0.0170479 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0170362 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0170332 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0169422 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0169108 |
| TCIM | transcriptional and immune response regulator | -0.016774 |
| RAB10 | RAB10, member RAS oncogene family | -0.016619 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0165953 |
| FYB1 | FYN binding protein 1 | -0.0165425 |
| TCF12 | transcription factor 12 | -0.0165367 |
| TPM1 | tropomyosin 1 (alpha) | -0.016135 |
| INTS6 | integrator complex subunit 6 | -0.016093 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0160475 |
| PDE7B | phosphodiesterase 7B | -0.016021 |
| RPL35A | ribosomal protein L35a | -0.0158849 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0156644 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.0155381 |
| FOXP1 | forkhead box P1 | -0.0154599 |
| RPS5 | ribosomal protein S5 | -0.0153481 |
| PFN1 | profilin 1 | -0.0153366 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0153226 |
| PON2 | paraoxonase 2 | -0.0152523 |
| PDE10A | phosphodiesterase 10A | -0.0152073 |
| GOLGB1 | golgin B1 | -0.015159 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0150837 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0150164 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0148418 |
