| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC17 | mucin 17, cell surface associated | 0.360797 |
| FLNB | filamin B, beta | 0.284451 |
| PLEC | plectin | 0.153936 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109512 |
| NDRG1 | N-myc downstream regulated 1 | 0.0975071 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0971165 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0852792 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0815751 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0788489 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0784899 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.069633 |
| MCL1 | myeloid cell leukemia 1 | 0.0678514 |
| CORO1C | coronin, actin binding protein, 1C | 0.0673904 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656378 |
| PCBP2 | poly(rC) binding protein 2 | 0.0633838 |
| ACTN4 | actinin, alpha 4 | 0.0628558 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0624782 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0620614 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0614708 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0606904 |
| PGK1 | phosphoglycerate kinase 1 | 0.0605619 |
| DSPP | dentin sialophosphoprotein | 0.0602036 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0592834 |
| RCOR1 | REST corepressor 1 | 0.0591702 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0561248 |
| TPM3 | tropomyosin 3 | 0.0542978 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0539656 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0539508 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0538801 |
| FAM107B | family with sequence similarity 107, member B | 0.0507375 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0501234 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0496798 |
| MSN | moesin | 0.04797 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0478775 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0478093 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0470074 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.045513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0442069 |
| LAMB3 | laminin, beta 3 | 0.0437702 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0433725 |
| ITGA6 | integrin, alpha 6 | 0.0430093 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0429616 |
| EZR | ezrin | 0.0428789 |
| PARD3 | par-3 family cell polarity regulator | 0.0426744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0423618 |
| FMNL2 | formin-like 2 | 0.0420335 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0415375 |
| SPAG9 | sperm associated antigen 9 | 0.0415172 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.041379 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0401298 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0398809 |
| LAMC2 | laminin, gamma 2 | 0.0393385 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0384278 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0381997 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0381511 |
| CAPRIN2 | caprin family member 2 | 0.0378635 |
| NCOR2 | nuclear receptor corepressor 2 | 0.037266 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0366788 |
| SNX9 | sorting nexin 9 | 0.036229 |
| KRT18 | keratin 18, type I | 0.0346934 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0342995 |
| OGA | O-GlcNAcase | 0.0342387 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0342163 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0335547 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.033208 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0328156 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0326073 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0319132 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0318076 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0317573 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0316722 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.03166 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0315203 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0298537 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0293405 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.02911 |
| YTHDC1 | YTH domain containing 1 | 0.0289646 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0289492 |
| TGM2 | transglutaminase 2 | 0.0289084 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0288941 |
| FAM13A | family with sequence similarity 13, member A | 0.028891 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0287834 |
| NUP58 | nucleoporin 58 | 0.0286664 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284667 |
| CTBP2 | C-terminal binding protein 2 | 0.028242 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0277287 |
| RPL19 | ribosomal protein L19 | 0.0274635 |
| CCNY | cyclin Y | 0.0273365 |
| UBC | ubiquitin C | 0.0271313 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0270079 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0267287 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0267233 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.026634 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026615 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0264936 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0264748 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0264702 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0261537 |
| FNDC3B | fibronectin type III domain containing 3B | 0.026126 |
| SEPTIN9 | septin 9 | 0.0260112 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.159685 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.128341 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.103598 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.10254 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0819442 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0785932 |
| S100A10 | S100 calcium binding protein A10 | -0.0630291 |
| ACTG1 | actin gamma 1 | -0.0512717 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0496496 |
| PRSS3 | protease, serine, 3 | -0.0490411 |
| VCAN | versican | -0.0488147 |
| EFNA5 | ephrin-A5 | -0.0473563 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0452461 |
| RPL34 | ribosomal protein L34 | -0.0433605 |
| S100A4 | S100 calcium binding protein A4 | -0.0422227 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0418323 |
| RPL8 | ribosomal protein L8 | -0.0403078 |
| RPS21 | ribosomal protein S21 | -0.0396624 |
| RPL35A | ribosomal protein L35a | -0.0394042 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0385939 |
| PTMA | prothymosin, alpha | -0.0383056 |
| RPS24 | ribosomal protein S24 | -0.0374666 |
| RRBP1 | ribosome binding protein 1 | -0.0367979 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.036532 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0360526 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353482 |
| RPL12 | ribosomal protein L12 | -0.0347345 |
| RPLP0 | ribosomal protein, large, P0 | -0.0346076 |
| KLF6 | Kruppel-like factor 6 | -0.0342665 |
| TXNRD1 | thioredoxin reductase 1 | -0.0340984 |
| RPL30 | ribosomal protein L30 | -0.0329793 |
| EHBP1 | EH domain binding protein 1 | -0.0325616 |
| RPL37A | ribosomal protein L37a | -0.0320009 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.031403 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0312869 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.030496 |
| RPS13 | ribosomal protein S13 | -0.0303709 |
| FTL | ferritin, light polypeptide | -0.0301695 |
| RPS27A | ribosomal protein S27a | -0.0297715 |
| SQSTM1 | sequestosome 1 | -0.0290604 |
| EPCAM | epithelial cell adhesion molecule | -0.0288655 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0288227 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0278967 |
| THOC2 | THO complex 2 | -0.027826 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.027733 |
| S100A6 | S100 calcium binding protein A6 | -0.0271637 |
| CALU | calumenin | -0.0270209 |
| MORF4L2 | mortality factor 4 like 2 | -0.0267795 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0266392 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0265581 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0262922 |
| GNAS | GNAS complex locus | -0.0259327 |
| HMGA2 | high mobility group AT-hook 2 | -0.0255955 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0255615 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0255041 |
| RACK1 | receptor for activated C kinase 1 | -0.0254997 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0251517 |
| ANXA2 | annexin A2 | -0.0251116 |
| MYOF | myoferlin | -0.0250794 |
| RPS8 | ribosomal protein S8 | -0.0248147 |
| RPL26 | ribosomal protein L26 | -0.0247638 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.024675 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0246498 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0246105 |
| RPS3 | ribosomal protein S3 | -0.0244699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0240578 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0240268 |
| CD2AP | CD2-associated protein | -0.0239571 |
| RPL37 | ribosomal protein L37 | -0.0237163 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.023641 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0235953 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0235607 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226974 |
| IER3 | immediate early response 3 | -0.0226421 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.022625 |
| PRELID2 | PRELI domain containing 2 | -0.0223985 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0222851 |
| S100A11 | S100 calcium binding protein A11 | -0.0222146 |
| JMJD1C | jumonji domain containing 1C | -0.0218776 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0215178 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0213261 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0209758 |
| RPL9 | ribosomal protein L9 | -0.0209688 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0209616 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0208684 |
| ARF1 | ADP-ribosylation factor 1 | -0.0207089 |
| RPLP2 | ribosomal protein, large, P2 | -0.0203517 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0202547 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0201273 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.020081 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0198562 |
| RIGI | RNA sensor RIG-I | -0.0197777 |
| RPS28 | ribosomal protein S28 | -0.019496 |
| RTN3 | reticulon 3 | -0.0191244 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0191126 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0186654 |
| RPS6 | ribosomal protein S6 | -0.0186545 |
| SDC4 | syndecan 4 | -0.0185191 |
| RPL31 | ribosomal protein L31 | -0.0184596 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0183745 |