| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LASP1 | LIM and SH3 protein 1 | 0.0966096 |
| CEP250 | centrosomal protein 250kDa | 0.0862208 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0642624 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0616862 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0462962 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0461009 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0409266 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.039495 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0378959 |
| LRRC59 | leucine rich repeat containing 59 | 0.0358472 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.034594 |
| PLEC | plectin | 0.0344336 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0337356 |
| ACTN4 | actinin, alpha 4 | 0.0336588 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0327692 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0308314 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0301742 |
| MCL1 | myeloid cell leukemia 1 | 0.0293442 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0287065 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0277311 |
| GSE1 | Gse1 coiled-coil protein | 0.0277077 |
| MSI2 | musashi RNA-binding protein 2 | 0.0276709 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.027644 |
| DTNA | dystrobrevin, alpha | 0.0274863 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268462 |
| MYO5B | myosin VB | 0.0254709 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0251776 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0250655 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0229778 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0217769 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.021443 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0210868 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0210802 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209973 |
| FOXO3 | forkhead box O3 | 0.020957 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0208341 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0206389 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0205515 |
| GSDMB | gasdermin B | 0.0204408 |
| FLNA | filamin A, alpha | 0.0202891 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0192686 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0188052 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0184484 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0179531 |
| KIF1A | kinesin family member 1A | 0.017662 |
| FGF13 | fibroblast growth factor 13 | 0.01766 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0175404 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0169769 |
| FAM219A | family with sequence similarity 219, member A | 0.0167394 |
| FASN | fatty acid synthase | 0.0167393 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0167042 |
| RELT | RELT tumor necrosis factor receptor | 0.0166958 |
| DENND1A | DENN/MADD domain containing 1A | 0.016416 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0163248 |
| KIF16B | kinesin family member 16B | 0.0162297 |
| INTS6 | integrator complex subunit 6 | 0.0160489 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0158636 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0156882 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0156756 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0152409 |
| DENND5A | DENN/MADD domain containing 5A | 0.0152251 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0150053 |
| RCOR1 | REST corepressor 1 | 0.0147644 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0145571 |
| TBL1X | transducin (beta)-like 1X-linked | 0.014537 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0145115 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0142457 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0142011 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.014154 |
| PPP1R9B | protein phosphatase 1, regulatory subunit 9B | 0.0140911 |
| TENM2 | teneurin transmembrane protein 2 | 0.0139891 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.013968 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0139336 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0139191 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0136811 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0136718 |
| HELZ | helicase with zinc finger | 0.0136557 |
| PRELID2 | PRELI domain containing 2 | 0.0135424 |
| SQSTM1 | sequestosome 1 | 0.0135011 |
| KRT86 | keratin 86, type II | 0.0134256 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0133781 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0133738 |
| SMAD3 | SMAD family member 3 | 0.0133578 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0133462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.013337 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0132959 |
| FLNB | filamin B, beta | 0.0131876 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0131322 |
| MLPH | melanophilin | 0.0130661 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0130404 |
| KRT18 | keratin 18, type I | 0.0129695 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0129501 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0127944 |
| DIDO1 | death inducer-obliterator 1 | 0.0127726 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0127672 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0125932 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0125252 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0124869 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0122909 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.012286 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.217643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122533 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.083543 |
| MT2A | metallothionein 2A | -0.0794609 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0777663 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0731578 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0663367 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0638267 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0590147 |
| ASPH | aspartate beta-hydroxylase | -0.0530094 |
| ACTG1 | actin gamma 1 | -0.0521979 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0506005 |
| CCNI | cyclin I | -0.0491608 |
| S100A9 | S100 calcium binding protein A9 | -0.0479764 |
| RPS6 | ribosomal protein S6 | -0.0449016 |
| PTMA | prothymosin, alpha | -0.0443392 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0428758 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0417018 |
| S100A8 | S100 calcium binding protein A8 | -0.0407851 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0405853 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0405726 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0405335 |
| B2M | beta-2-microglobulin | -0.039447 |
| RPS3 | ribosomal protein S3 | -0.0389888 |
| RPL35A | ribosomal protein L35a | -0.0387813 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0385735 |
| CLTC | clathrin, heavy chain (Hc) | -0.0382741 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0378833 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0377599 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0359489 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0350282 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0343726 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0332859 |
| RPL19 | ribosomal protein L19 | -0.0326326 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0325578 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0313595 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0308907 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0307787 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0303083 |
| VMP1 | vacuole membrane protein 1 | -0.0300995 |
| POTEF | POTE ankyrin domain family, member F | -0.0299558 |
| OSMR | oncostatin M receptor | -0.0298672 |
| TMC5 | transmembrane channel-like 5 | -0.0276786 |
| FTL | ferritin, light polypeptide | -0.0271588 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0269471 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0265692 |
| TMSB10 | thymosin beta 10 | -0.0265029 |
| NTN4 | netrin 4 | -0.0263909 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0259013 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0256285 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.025164 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0251445 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0250195 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0246413 |
| RPS8 | ribosomal protein S8 | -0.0246074 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0244723 |
| SMIM14 | small integral membrane protein 14 | -0.0242661 |
| RPL12 | ribosomal protein L12 | -0.0237042 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0236896 |
| PERP | PERP, TP53 apoptosis effector | -0.0236204 |
| LDHA | lactate dehydrogenase A | -0.0235028 |
| RPL8 | ribosomal protein L8 | -0.0232803 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0232455 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0231579 |
| SERINC3 | serine incorporator 3 | -0.0230397 |
| NCOA6 | nuclear receptor coactivator 6 | -0.022966 |
| TMEM165 | transmembrane protein 165 | -0.0228781 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0227528 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0226529 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0226491 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225346 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0225215 |
| PKM | pyruvate kinase, muscle | -0.022355 |
| PFN1 | profilin 1 | -0.0222488 |
| AREG | amphiregulin | -0.0222168 |
| S100A14 | S100 calcium binding protein A14 | -0.0221227 |
| RPLP0 | ribosomal protein, large, P0 | -0.0217616 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0216822 |
| RPS19 | ribosomal protein S19 | -0.0215697 |
| SERF2 | small EDRK-rich factor 2 | -0.0215595 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0214737 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.021327 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0212671 |
| TXNRD1 | thioredoxin reductase 1 | -0.0211917 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0211093 |
| TUBA1B | tubulin, alpha 1b | -0.02102 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0209385 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0207668 |
| FNBP1 | formin binding protein 1 | -0.020634 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.020475 |
| WDR45B | WD repeat domain 45B | -0.0203709 |
| RPLP1 | ribosomal protein, large, P1 | -0.0203077 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0203048 |
| MIEN1 | migration and invasion enhancer 1 | -0.0202279 |
| GNAS | GNAS complex locus | -0.0202214 |
| PRR11 | proline rich 11 | -0.0201696 |
| RPL7A | ribosomal protein L7a | -0.0200999 |
| ANXA2 | annexin A2 | -0.0200079 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0199755 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0199517 |
