| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.168428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.166977 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.141021 |
| FLNB | filamin B, beta | 0.120513 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.115727 |
| VIM | vimentin | 0.107391 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.106326 |
| MCL1 | myeloid cell leukemia 1 | 0.104512 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.102811 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.101927 |
| RPL19 | ribosomal protein L19 | 0.101625 |
| ACTN4 | actinin, alpha 4 | 0.100949 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100115 |
| PGK1 | phosphoglycerate kinase 1 | 0.09475 |
| ENO1 | enolase 1, (alpha) | 0.0905217 |
| LASP1 | LIM and SH3 protein 1 | 0.0870393 |
| SMAD3 | SMAD family member 3 | 0.0869689 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0868688 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0842265 |
| CCNY | cyclin Y | 0.0829903 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0821296 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0816416 |
| TMSB4X | thymosin beta 4, X-linked | 0.0807212 |
| FLNA | filamin A, alpha | 0.0791909 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0765893 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0739797 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.073289 |
| CALR | calreticulin | 0.072244 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0719492 |
| FAM13A | family with sequence similarity 13, member A | 0.0704092 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.069597 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0695766 |
| APP | amyloid beta (A4) precursor protein | 0.0686282 |
| PLEC | plectin | 0.0671186 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0664665 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0653633 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0652507 |
| ANXA2 | annexin A2 | 0.0631252 |
| PLAU | plasminogen activator, urokinase | 0.0626622 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0598939 |
| KRT19 | keratin 19, type I | 0.0584134 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0582494 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0572486 |
| KRT18 | keratin 18, type I | 0.0572022 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0569651 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0566203 |
| TMSB10 | thymosin beta 10 | 0.0550914 |
| PFKP | phosphofructokinase, platelet | 0.0547067 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0538576 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0526298 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0524245 |
| OGA | O-GlcNAcase | 0.0523758 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0518547 |
| SPAG9 | sperm associated antigen 9 | 0.0512495 |
| HPCAL1 | hippocalcin-like 1 | 0.0495256 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0481538 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0474911 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0460692 |
| HELZ | helicase with zinc finger | 0.0460651 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0445523 |
| ASPH | aspartate beta-hydroxylase | 0.0444995 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0444318 |
| HMGA1 | high mobility group AT-hook 1 | 0.0437904 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0435751 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0431141 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0427701 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0424989 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0423149 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0409593 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0409248 |
| RNF213 | ring finger protein 213 | 0.0406272 |
| EZR | ezrin | 0.0404507 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0390588 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0389794 |
| LOC112694756 | uncharaterized LOC112694756 | 0.038623 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0377821 |
| CMIP | c-Maf inducing protein | 0.0377519 |
| JUP | junction plakoglobin | 0.0377399 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375195 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0372135 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0371568 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0365809 |
| FAM162A | family with sequence similarity 162, member A | 0.0363765 |
| NDRG1 | N-myc downstream regulated 1 | 0.0362412 |
| RIOK3 | RIO kinase 3 | 0.0360739 |
| TGM2 | transglutaminase 2 | 0.0360108 |
| FNBP1L | formin binding protein 1-like | 0.0359855 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0359025 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0357669 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0355842 |
| IRF6 | interferon regulatory factor 6 | 0.0355655 |
| MMP7 | matrix metallopeptidase 7 | 0.0352543 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0350566 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0349275 |
| KRT8 | keratin 8, type II | 0.0348142 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0348089 |
| FAT1 | FAT atypical cadherin 1 | 0.0348052 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0344042 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0341328 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0341018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205615 |
| MT2A | metallothionein 2A | -0.0962926 |
| HLA-B | major histocompatibility complex, class I, B | -0.0858036 |
| B2M | beta-2-microglobulin | -0.07146 |
| POTEF | POTE ankyrin domain family, member F | -0.0639139 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0552518 |
| RPS2 | ribosomal protein S2 | -0.0538368 |
| RPS6 | ribosomal protein S6 | -0.0506651 |
| FAM3C | family with sequence similarity 3, member C | -0.0481718 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0469143 |
| CDCP1 | CUB domain containing protein 1 | -0.0465705 |
| ACTG1 | actin gamma 1 | -0.0457327 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.044954 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0429926 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0427451 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0395438 |
| EFNA5 | ephrin-A5 | -0.0386438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0378718 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0374308 |
| NRP1 | neuropilin 1 | -0.0352723 |
| RPS29 | ribosomal protein S29 | -0.0347242 |
| RPL9 | ribosomal protein L9 | -0.034612 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0344164 |
| JMJD1C | jumonji domain containing 1C | -0.0340068 |
| OSMR | oncostatin M receptor | -0.0338657 |
| RPS21 | ribosomal protein S21 | -0.032573 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0320461 |
| EGR1 | early growth response 1 | -0.0302735 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030082 |
| RPS8 | ribosomal protein S8 | -0.0298143 |
| DSG2 | desmoglein 2 | -0.029624 |
| TMC5 | transmembrane channel-like 5 | -0.0293702 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0289268 |
| MT1X | metallothionein 1X | -0.0288778 |
| RPL34 | ribosomal protein L34 | -0.028798 |
| CLTC | clathrin, heavy chain (Hc) | -0.0285085 |
| CCNI | cyclin I | -0.0284398 |
| LCN2 | lipocalin 2 | -0.0280413 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275037 |
| FBXO11 | F-box protein 11 | -0.0271838 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0271196 |
| RBM25 | RNA binding motif protein 25 | -0.0264698 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0264583 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0259234 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0258111 |
| MX2 | MX dynamin-like GTPase 2 | -0.0256018 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0254084 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0253824 |
| RPL38 | ribosomal protein L38 | -0.0251186 |
| IER3 | immediate early response 3 | -0.0246464 |
| SYNRG | synergin, gamma | -0.0246273 |
| BPTF | bromodomain PHD finger transcription factor | -0.0245932 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0245828 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.024213 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0241367 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0241271 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0237488 |
| TMEM165 | transmembrane protein 165 | -0.0237137 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0234693 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0234468 |
| DENND4A | DENN/MADD domain containing 4A | -0.0234418 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0232131 |
| RPL37A | ribosomal protein L37a | -0.0231255 |
| CP | ceruloplasmin (ferroxidase) | -0.0227116 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0226391 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.022406 |
| TXNIP | thioredoxin interacting protein | -0.0222815 |
| RPS13 | ribosomal protein S13 | -0.0220769 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0219535 |
| PMP22 | peripheral myelin protein 22 | -0.0218793 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0217076 |
| AREG | amphiregulin | -0.0216559 |
| GOLGB1 | golgin B1 | -0.0214393 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0213229 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0209317 |
| EPCAM | epithelial cell adhesion molecule | -0.0208272 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0207743 |
| RPS24 | ribosomal protein S24 | -0.0207048 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0206758 |
| RPL8 | ribosomal protein L8 | -0.0205302 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0204776 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0203104 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0202835 |
| NABP1 | nucleic acid binding protein 1 | -0.0200875 |
| S100A9 | S100 calcium binding protein A9 | -0.0200573 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0200515 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0196855 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0196667 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0195749 |
| RPL28 | ribosomal protein L28 | -0.0192555 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0191896 |
| MTDH | metadherin | -0.0190831 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0189847 |
| RPL31 | ribosomal protein L31 | -0.0189487 |
| NUMB | numb homolog (Drosophila) | -0.0189457 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0189343 |
| H3-3B | H3.3 histone B | -0.0188439 |
| RTN4 | reticulon 4 | -0.0185226 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0185153 |
| KIAA1217 | KIAA1217 | -0.0184168 |
