| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.162374 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.112803 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0893242 |
| LMO7 | LIM domain 7 | 0.074462 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.070411 |
| NDRG1 | N-myc downstream regulated 1 | 0.063821 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0615959 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0558187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0552874 |
| GOLGB1 | golgin B1 | 0.0486532 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0475667 |
| RNF43 | ring finger protein 43 | 0.0472987 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0468239 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0462685 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0460555 |
| PRELID2 | PRELI domain containing 2 | 0.0457523 |
| COG6 | component of oligomeric golgi complex 6 | 0.0446326 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.044629 |
| RUNX1 | runt-related transcription factor 1 | 0.0443652 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0437324 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0412651 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0403001 |
| SEC24D | SEC24 family member D | 0.0394463 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0391297 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0389383 |
| SERINC5 | serine incorporator 5 | 0.0385503 |
| PTEN | phosphatase and tensin homolog | 0.0376911 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0375668 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0375247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0361183 |
| DSPP | dentin sialophosphoprotein | 0.0360377 |
| HDAC4 | histone deacetylase 4 | 0.0356259 |
| ARGLU1 | arginine and glutamate rich 1 | 0.035175 |
| FNIP1 | folliculin interacting protein 1 | 0.0349594 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0347386 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0346078 |
| NCKAP5 | NCK-associated protein 5 | 0.0344549 |
| GOLGA4 | golgin A4 | 0.0338959 |
| SMAD3 | SMAD family member 3 | 0.0338371 |
| HDLBP | high density lipoprotein binding protein | 0.0338072 |
| IFNGR1 | interferon gamma receptor 1 | 0.0335766 |
| DSTN | destrin (actin depolymerizing factor) | 0.0334697 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0332374 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0325241 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0323857 |
| SBF2 | SET binding factor 2 | 0.032325 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0322229 |
| USP3 | ubiquitin specific peptidase 3 | 0.0320449 |
| EFNB2 | ephrin-B2 | 0.0305996 |
| UBC | ubiquitin C | 0.030361 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302285 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0301591 |
| KIF16B | kinesin family member 16B | 0.029971 |
| RNF149 | ring finger protein 149 | 0.0297786 |
| ABHD2 | abhydrolase domain containing 2 | 0.0296865 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0295837 |
| DIAPH3 | diaphanous-related formin 3 | 0.0295271 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0294043 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.029255 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0290617 |
| MEIS2 | Meis homeobox 2 | 0.0290204 |
| HYOU1 | hypoxia up-regulated 1 | 0.0289771 |
| HELZ | helicase with zinc finger | 0.0286776 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0286704 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0286156 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0285562 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0284508 |
| GSE1 | Gse1 coiled-coil protein | 0.0283681 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0281988 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0280632 |
| OGA | O-GlcNAcase | 0.0275227 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0272324 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0268959 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0268495 |
| TXNIP | thioredoxin interacting protein | 0.0267369 |
| FOSL2 | FOS-like antigen 2 | 0.0265966 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0265727 |
| CCNL1 | cyclin L1 | 0.0264064 |
| USP47 | ubiquitin specific peptidase 47 | 0.0262317 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0262231 |
| PMM2 | phosphomannomutase 2 | 0.0261282 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0261046 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.026024 |
| FAT1 | FAT atypical cadherin 1 | 0.0259603 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0259049 |
| SUCO | SUN domain containing ossification factor | 0.0256912 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0254732 |
| ZNF292 | zinc finger protein 292 | 0.0251423 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0249119 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.024837 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.024779 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0247533 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.024707 |
| CENPF | centromere protein F, 350/400kDa | 0.0246978 |
| COPA | coatomer protein complex, subunit alpha | 0.0245663 |
| MLEC | malectin | 0.024545 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0244124 |
| CDC42SE2 | CDC42 small effector 2 | 0.0242771 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0242255 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0241006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.16905 |
| LYZ | lysozyme | -0.112514 |
| XAF1 | XIAP associated factor 1 | -0.102302 |
| RIGI | RNA sensor RIG-I | -0.0974508 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.092247 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0872693 |
| B2M | beta-2-microglobulin | -0.0870528 |
| LCN2 | lipocalin 2 | -0.0855617 |
| MX2 | MX dynamin-like GTPase 2 | -0.0839757 |
| SP100 | SP100 nuclear antigen | -0.0835866 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0831292 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0773593 |
| RNF213 | ring finger protein 213 | -0.0727189 |
| PTMA | prothymosin, alpha | -0.072402 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0697026 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0674577 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0669979 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0638304 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0624592 |
| TMC5 | transmembrane channel-like 5 | -0.0618974 |
| HLA-B | major histocompatibility complex, class I, B | -0.059509 |
| NPSR1 | neuropeptide S receptor 1 | -0.0588346 |
| EGR1 | early growth response 1 | -0.0555031 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0540159 |
| EPHB2 | EPH receptor B2 | -0.0527404 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0521828 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0517306 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0495498 |
| AREG | amphiregulin | -0.048136 |
| JUN | jun proto-oncogene | -0.0471933 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0466316 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0453635 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0452262 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0437818 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0436438 |
| ANXA2 | annexin A2 | -0.0419436 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0418922 |
| ATP10B | ATPase, class V, type 10B | -0.0400584 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0392316 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0383231 |
| MT2A | metallothionein 2A | -0.0374107 |
| SSH2 | slingshot protein phosphatase 2 | -0.0368243 |
| SPATA13 | spermatogenesis associated 13 | -0.0367394 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0364392 |
| PMP22 | peripheral myelin protein 22 | -0.0361121 |
| SQSTM1 | sequestosome 1 | -0.036063 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0358739 |
| PTGR1 | prostaglandin reductase 1 | -0.0353894 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.034986 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0349859 |
| MX1 | MX dynamin-like GTPase 1 | -0.0349632 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0342332 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0340124 |
| ITGA6 | integrin, alpha 6 | -0.0338716 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0329074 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0326886 |
| TMSB10 | thymosin beta 10 | -0.0326011 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0322703 |
| PRKCA | protein kinase C, alpha | -0.032046 |
| H1-0 | H1.0 linker histone | -0.031669 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0311336 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0309423 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0307985 |
| TFRC | transferrin receptor | -0.0306911 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0301686 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0301141 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0300372 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.029862 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0296186 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0295661 |
| TRIM56 | tripartite motif containing 56 | -0.0289023 |
| KLF6 | Kruppel-like factor 6 | -0.0282512 |
| CLYBL | citrate lyase beta like | -0.0280394 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0279854 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0279585 |
| FTL | ferritin, light polypeptide | -0.0276541 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0275352 |
| ITGA1 | integrin, alpha 1 | -0.0266942 |
| MUC13 | mucin 13, cell surface associated | -0.0264073 |
| POF1B | premature ovarian failure, 1B | -0.0261244 |
| MUC20 | mucin 20, cell surface associated | -0.0260093 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0259164 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0257546 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257415 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0254262 |
| ACTG1 | actin gamma 1 | -0.0249204 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0242115 |
| PLSCR1 | phospholipid scramblase 1 | -0.0241793 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0240946 |
| ERBIN | erbb2 interacting protein | -0.024018 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0236007 |
| FHIT | fragile histidine triad | -0.0235181 |
| NF1 | neurofibromin 1 | -0.0234122 |
| GPX2 | glutathione peroxidase 2 | -0.0233661 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0232651 |
| TNS4 | tensin 4 | -0.0231666 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0231008 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0229385 |
| APOL1 | apolipoprotein L, 1 | -0.0228823 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0226333 |
