| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.241009 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109538 |
| FNDC3B | fibronectin type III domain containing 3B | 0.10913 |
| EGFR | epidermal growth factor receptor | 0.0941585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0869824 |
| SMAD3 | SMAD family member 3 | 0.0854489 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0798439 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.075625 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0726095 |
| LOXL2 | lysyl oxidase-like 2 | 0.071592 |
| NDRG1 | N-myc downstream regulated 1 | 0.0715832 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0693776 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0565603 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.055274 |
| CADM1 | cell adhesion molecule 1 | 0.0544181 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0538082 |
| CANX | calnexin | 0.052602 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0514515 |
| OGA | O-GlcNAcase | 0.0493161 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0485916 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0483885 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0470288 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0468535 |
| AHNAK | AHNAK nucleoprotein | 0.0467715 |
| STC1 | stanniocalcin 1 | 0.0467674 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0449556 |
| FAM13A | family with sequence similarity 13, member A | 0.0447561 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0438855 |
| SBF2 | SET binding factor 2 | 0.0426674 |
| FLNA | filamin A, alpha | 0.0410988 |
| HELZ | helicase with zinc finger | 0.0397337 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0395523 |
| COG5 | component of oligomeric golgi complex 5 | 0.0395518 |
| TNS3 | tensin 3 | 0.0392043 |
| DST | dystonin | 0.0390314 |
| PLEC | plectin | 0.039001 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0384557 |
| ATP13A3 | ATPase type 13A3 | 0.0383458 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0382842 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.038088 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0380384 |
| ANO6 | anoctamin 6 | 0.0376716 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0359453 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0359131 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0356419 |
| TNNC1 | troponin C type 1 (slow) | 0.0349205 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0345512 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.034148 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0341446 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0340783 |
| INHBA | inhibin, beta A | 0.0337326 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0335775 |
| GOLGB1 | golgin B1 | 0.0334634 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0333027 |
| LRRC49 | leucine rich repeat containing 49 | 0.0332983 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0330823 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0329547 |
| COL5A1 | collagen, type V, alpha 1 | 0.0329351 |
| MSN | moesin | 0.0328987 |
| SEC24D | SEC24 family member D | 0.0324909 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0321948 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0319595 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0317968 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0314217 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308001 |
| HDLBP | high density lipoprotein binding protein | 0.0307538 |
| PRELID2 | PRELI domain containing 2 | 0.0304275 |
| APP | amyloid beta (A4) precursor protein | 0.0302533 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0301828 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0299496 |
| RTN4 | reticulon 4 | 0.0298196 |
| FLNB | filamin B, beta | 0.0297792 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0297635 |
| GOLGA3 | golgin A3 | 0.0297315 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0297294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0295662 |
| SMYD3 | SET and MYND domain containing 3 | 0.029259 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0292189 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0291541 |
| SETD5 | SET domain containing 5 | 0.0287078 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0285228 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.028412 |
| MYOF | myoferlin | 0.0283227 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0283165 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0282684 |
| GLIS3 | GLIS family zinc finger 3 | 0.0280464 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0278615 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0272325 |
| ATXN1 | ataxin 1 | 0.0270868 |
| CORO1C | coronin, actin binding protein, 1C | 0.0265889 |
| TPM3 | tropomyosin 3 | 0.0263863 |
| ZNF292 | zinc finger protein 292 | 0.0262365 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0262171 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.026175 |
| YEATS2 | YEATS domain containing 2 | 0.0260435 |
| CLTC | clathrin, heavy chain (Hc) | 0.0259911 |
| ASPH | aspartate beta-hydroxylase | 0.025675 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0254137 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0254063 |
| GPR107 | G protein-coupled receptor 107 | 0.0253323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25749 |
| TMSB10 | thymosin beta 10 | -0.160625 |
| FTL | ferritin, light polypeptide | -0.140977 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.140189 |
| MT2A | metallothionein 2A | -0.12125 |
| VIM | vimentin | -0.101806 |
| B2M | beta-2-microglobulin | -0.0837637 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0801166 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0785981 |
| HLA-B | major histocompatibility complex, class I, B | -0.0735426 |
| PTMA | prothymosin, alpha | -0.0647671 |
| RPS6 | ribosomal protein S6 | -0.0624748 |
| NLGN1 | neuroligin 1 | -0.0574382 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0529541 |
| POTEF | POTE ankyrin domain family, member F | -0.0525994 |
| RPL35A | ribosomal protein L35a | -0.0525967 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0463212 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.045812 |
| RPS8 | ribosomal protein S8 | -0.0457408 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0456464 |
| TPM4 | tropomyosin 4 | -0.0444769 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0427679 |
| HLA-A | major histocompatibility complex, class I, A | -0.0419819 |
| FN1 | fibronectin 1 | -0.0386291 |
| TPI1 | triosephosphate isomerase 1 | -0.0369742 |
| EGR1 | early growth response 1 | -0.036566 |
| IGF2 | insulin-like growth factor 2 | -0.0350896 |
| RPS13 | ribosomal protein S13 | -0.0347919 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0339728 |
| SEC61G | Sec61 gamma subunit | -0.0339248 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0338771 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0338664 |
| ACTG1 | actin gamma 1 | -0.0333128 |
| RPL28 | ribosomal protein L28 | -0.0323547 |
| PRSS23 | protease, serine, 23 | -0.0316089 |
| RPS19 | ribosomal protein S19 | -0.0307534 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0306198 |
| S100A9 | S100 calcium binding protein A9 | -0.0294967 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290263 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0283261 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278299 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0275462 |
| PFN1 | profilin 1 | -0.0257921 |
| RPL23 | ribosomal protein L23 | -0.0257759 |
| S100A6 | S100 calcium binding protein A6 | -0.0256365 |
| GNAS | GNAS complex locus | -0.0256126 |
| RPL34 | ribosomal protein L34 | -0.0254975 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0254819 |
| RPL9 | ribosomal protein L9 | -0.0254062 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0251414 |
| RPL37A | ribosomal protein L37a | -0.0249556 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246907 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0240319 |
| RPL31 | ribosomal protein L31 | -0.0236829 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0234872 |
| RPS27A | ribosomal protein S27a | -0.0232653 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0230283 |
| RPL12 | ribosomal protein L12 | -0.0223884 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0222613 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0218804 |
| RPS21 | ribosomal protein S21 | -0.021503 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0213017 |
| CTSD | cathepsin D | -0.0211437 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0210723 |
| MT1X | metallothionein 1X | -0.0209428 |
| CBX3 | chromobox homolog 3 | -0.0207975 |
| H3-3B | H3.3 histone B | -0.0205849 |
| RPLP0 | ribosomal protein, large, P0 | -0.0204543 |
| RPS16 | ribosomal protein S16 | -0.0199245 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0199132 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0199025 |
| ZNF804A | zinc finger protein 804A | -0.0198856 |
| ASTN2 | astrotactin 2 | -0.0197266 |
| LMNA | lamin A/C | -0.0196303 |
| RPS14 | ribosomal protein S14 | -0.0195467 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0194247 |
| RACK1 | receptor for activated C kinase 1 | -0.0193283 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0192925 |
| CCND1 | cyclin D1 | -0.019241 |
| PKM | pyruvate kinase, muscle | -0.0189169 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0186491 |
| CENPE | centromere protein E, 312kDa | -0.0186489 |
| RPL18 | ribosomal protein L18 | -0.0183182 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0182401 |
| CLMP | CXADR-like membrane protein | -0.0181202 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0181018 |
| RIGI | RNA sensor RIG-I | -0.017949 |
| RPS24 | ribosomal protein S24 | -0.0178395 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0177809 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0177359 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.017539 |
| TUBB4B | tubulin, beta 4B class IVb | -0.017456 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0174369 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0173832 |
| RPL36 | ribosomal protein L36 | -0.017179 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0171611 |
| ENO1 | enolase 1, (alpha) | -0.0170125 |
| RPS3 | ribosomal protein S3 | -0.0168067 |
| CA9 | carbonic anhydrase IX | -0.0166797 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0165327 |
