| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.13119 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.104973 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10318 |
| COL5A1 | collagen, type V, alpha 1 | 0.103019 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0966229 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0841275 |
| PLEC | plectin | 0.0758454 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0720443 |
| SEPTIN9 | septin 9 | 0.0688466 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0680209 |
| NAV1 | neuron navigator 1 | 0.0610653 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0550627 |
| HMGA2 | high mobility group AT-hook 2 | 0.0536321 |
| NAV2 | neuron navigator 2 | 0.0532352 |
| CDH13 | cadherin 13 | 0.0508248 |
| FLNA | filamin A, alpha | 0.0464161 |
| MYO10 | myosin X | 0.0460438 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0455858 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0440755 |
| LOXL2 | lysyl oxidase-like 2 | 0.0421631 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0410766 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0404979 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0383256 |
| SMAD3 | SMAD family member 3 | 0.0370535 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0356399 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0333174 |
| TNS1 | tensin 1 | 0.0314963 |
| LAMB3 | laminin, beta 3 | 0.0305142 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0300132 |
| PCBP3 | poly(rC) binding protein 3 | 0.0296832 |
| VCL | vinculin | 0.0288569 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0286093 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.028016 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0278935 |
| RASA3 | RAS p21 protein activator 3 | 0.0277345 |
| ACTN4 | actinin, alpha 4 | 0.0274782 |
| ACTN1 | actinin, alpha 1 | 0.0272897 |
| FLNB | filamin B, beta | 0.026988 |
| MCL1 | myeloid cell leukemia 1 | 0.0269397 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0266166 |
| RAI14 | retinoic acid induced 14 | 0.0264172 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0259075 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0258153 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0256823 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0255497 |
| CLMP | CXADR-like membrane protein | 0.024906 |
| MSN | moesin | 0.0247395 |
| AHNAK | AHNAK nucleoprotein | 0.0246189 |
| RRM2 | ribonucleotide reductase M2 | 0.0245084 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0243085 |
| GLIS3 | GLIS family zinc finger 3 | 0.0239609 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0237003 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0235419 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0230796 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0221874 |
| MLPH | melanophilin | 0.0217436 |
| L1CAM | L1 cell adhesion molecule | 0.0215894 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0215548 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.021537 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0212089 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0211873 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.020908 |
| HDLBP | high density lipoprotein binding protein | 0.0202392 |
| DIAPH2 | diaphanous-related formin 2 | 0.0199116 |
| INHBA | inhibin, beta A | 0.0196397 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0195138 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0192295 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0188726 |
| ASPH | aspartate beta-hydroxylase | 0.0187784 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0187766 |
| CAPRIN2 | caprin family member 2 | 0.0187146 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.018656 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0185465 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0185077 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0181249 |
| PRELID2 | PRELI domain containing 2 | 0.0179119 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0178553 |
| LASP1 | LIM and SH3 protein 1 | 0.0177753 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0177241 |
| FAM219A | family with sequence similarity 219, member A | 0.0173671 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0173194 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0167851 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0167774 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0166853 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0165888 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0164075 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163587 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0163092 |
| HJURP | Holliday junction recognition protein | 0.015927 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.015913 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0158888 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0158444 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0158253 |
| EGFR | epidermal growth factor receptor | 0.015621 |
| YEATS2 | YEATS domain containing 2 | 0.0155704 |
| CEP250 | centrosomal protein 250kDa | 0.0155208 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0154152 |
| STK10 | serine/threonine kinase 10 | 0.0154056 |
| CMIP | c-Maf inducing protein | 0.015391 |
| ATXN1 | ataxin 1 | 0.0153208 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.628547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133463 |
| MT2A | metallothionein 2A | -0.1141 |
| TMSB10 | thymosin beta 10 | -0.103821 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0790304 |
| RPS6 | ribosomal protein S6 | -0.07164 |
| EGR1 | early growth response 1 | -0.0715154 |
| FTL | ferritin, light polypeptide | -0.0672928 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0670033 |
| PTMA | prothymosin, alpha | -0.0620254 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0620192 |
| VIM | vimentin | -0.0596189 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0490296 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0463832 |
| NDRG1 | N-myc downstream regulated 1 | -0.0463064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0458457 |
| RPLP1 | ribosomal protein, large, P1 | -0.0446347 |
| IER3 | immediate early response 3 | -0.0444609 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0438919 |
| RPL35A | ribosomal protein L35a | -0.0416895 |
| FAM13A | family with sequence similarity 13, member A | -0.0398397 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0385089 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0381224 |
| ACTG1 | actin gamma 1 | -0.0380681 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0365173 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0363595 |
| RPS19 | ribosomal protein S19 | -0.036355 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0355753 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350689 |
| RPLP0 | ribosomal protein, large, P0 | -0.0347291 |
| RPS8 | ribosomal protein S8 | -0.0343349 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0339564 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0338502 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0337323 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0328169 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0326655 |
| S100A10 | S100 calcium binding protein A10 | -0.0314137 |
| STC1 | stanniocalcin 1 | -0.0312249 |
| RNF24 | ring finger protein 24 | -0.0304143 |
| RTN4 | reticulon 4 | -0.030344 |
| USP3 | ubiquitin specific peptidase 3 | -0.0300494 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296299 |
| GOLGA4 | golgin A4 | -0.0292969 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0290374 |
| RPL23 | ribosomal protein L23 | -0.0290001 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0289207 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0285812 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0285177 |
| MAP1B | microtubule-associated protein 1B | -0.028035 |
| CDCP1 | CUB domain containing protein 1 | -0.0277878 |
| MT1X | metallothionein 1X | -0.0277522 |
| RPL12 | ribosomal protein L12 | -0.0277179 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0277174 |
| ADM | adrenomedullin | -0.0275454 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0270318 |
| B2M | beta-2-microglobulin | -0.0269013 |
| LDHA | lactate dehydrogenase A | -0.0266681 |
| SYAP1 | synapse associated protein 1 | -0.0266333 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0265741 |
| CCNI | cyclin I | -0.0264055 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0262032 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.026161 |
| GNAS | GNAS complex locus | -0.0258987 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0258801 |
| FAM162A | family with sequence similarity 162, member A | -0.0258512 |
| SEC24A | SEC24 family member A | -0.0256143 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0255015 |
| RPL8 | ribosomal protein L8 | -0.0254944 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254394 |
| RPL32 | ribosomal protein L32 | -0.0253676 |
| RPLP2 | ribosomal protein, large, P2 | -0.0253615 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0253358 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0253132 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0252972 |
| RPL34 | ribosomal protein L34 | -0.0252674 |
| ZNF292 | zinc finger protein 292 | -0.0251381 |
| MORF4L2 | mortality factor 4 like 2 | -0.0247283 |
| PFN1 | profilin 1 | -0.0243666 |
| YBX1 | Y box binding protein 1 | -0.024337 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0239628 |
| RLF | rearranged L-myc fusion | -0.0238505 |
| WDR45B | WD repeat domain 45B | -0.0236891 |
| RPS16 | ribosomal protein S16 | -0.0236067 |
| JUN | jun proto-oncogene | -0.0236055 |
| PKM | pyruvate kinase, muscle | -0.0235936 |
| RPL11 | ribosomal protein L11 | -0.023447 |
| RACK1 | receptor for activated C kinase 1 | -0.0233385 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0228104 |
| LOX | lysyl oxidase | -0.0225524 |
| RPL9 | ribosomal protein L9 | -0.0224317 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0223643 |
| S100A6 | S100 calcium binding protein A6 | -0.0222233 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0220227 |
| ASTN2 | astrotactin 2 | -0.0217911 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0217204 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0216507 |
| TXNRD1 | thioredoxin reductase 1 | -0.0214039 |
| RPS13 | ribosomal protein S13 | -0.021166 |
| RBM39 | RNA binding motif protein 39 | -0.0211489 |
| S100A9 | S100 calcium binding protein A9 | -0.0207565 |
