| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.361093 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.279791 |
| COL6A3 | collagen, type VI, alpha 3 | 0.19788 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.180701 |
| LOXL2 | lysyl oxidase-like 2 | 0.178709 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.167683 |
| PLEC | plectin | 0.072964 |
| CALR | calreticulin | 0.0676245 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0652651 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0632563 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0550784 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.053409 |
| FLNA | filamin A, alpha | 0.0494415 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0492882 |
| ATP13A3 | ATPase type 13A3 | 0.0485316 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0476526 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0407024 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0387997 |
| POSTN | periostin, osteoblast specific factor | 0.0387582 |
| SMAD3 | SMAD family member 3 | 0.0386992 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0384005 |
| ACTN4 | actinin, alpha 4 | 0.0376534 |
| ARRDC3 | arrestin domain containing 3 | 0.037526 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0366511 |
| MTSS1 | metastasis suppressor 1 | 0.0353626 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0349432 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0340721 |
| CADM1 | cell adhesion molecule 1 | 0.0335897 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.033345 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0332571 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0321308 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320814 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.031033 |
| FAT1 | FAT atypical cadherin 1 | 0.0293045 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0275031 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0269519 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0253246 |
| ADM | adrenomedullin | 0.024907 |
| RPL19 | ribosomal protein L19 | 0.0246675 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0245171 |
| SQLE | squalene epoxidase | 0.0245017 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0243532 |
| COL6A1 | collagen, type VI, alpha 1 | 0.023296 |
| CABIN1 | calcineurin binding protein 1 | 0.0231288 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0231265 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0230843 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0225949 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.022203 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0217016 |
| NAV2 | neuron navigator 2 | 0.0216739 |
| VEGFA | vascular endothelial growth factor A | 0.021473 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0214571 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0212023 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0208635 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0207671 |
| APP | amyloid beta (A4) precursor protein | 0.0205568 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0204251 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0200726 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0198497 |
| SEPTIN9 | septin 9 | 0.0198226 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0197168 |
| SPAG9 | sperm associated antigen 9 | 0.0197104 |
| MSN | moesin | 0.019618 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0195161 |
| GOLGA2 | golgin A2 | 0.0193944 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0191264 |
| PFKP | phosphofructokinase, platelet | 0.0188541 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0186935 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0185998 |
| MYO10 | myosin X | 0.0184905 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.018391 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0183814 |
| PYGL | phosphorylase, glycogen, liver | 0.0181918 |
| COL5A1 | collagen, type V, alpha 1 | 0.0178874 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0177501 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0176183 |
| CTSB | cathepsin B | 0.0176178 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0174698 |
| COL7A1 | collagen, type VII, alpha 1 | 0.017422 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0173778 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0172624 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0171201 |
| TNS1 | tensin 1 | 0.0169689 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0169669 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168715 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0166217 |
| RPL3 | ribosomal protein L3 | 0.0163901 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0160781 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0158737 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0158616 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0158405 |
| SDC2 | syndecan 2 | 0.015728 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0156868 |
| LASP1 | LIM and SH3 protein 1 | 0.0156568 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0156355 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0155934 |
| VIM | vimentin | 0.0155636 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0155496 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.015041 |
| MINK1 | misshapen-like kinase 1 | 0.0150387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.239157 |
| COL1A1 | collagen, type I, alpha 1 | -0.166347 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.102245 |
| ASPH | aspartate beta-hydroxylase | -0.0819429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0812325 |
| CDH13 | cadherin 13 | -0.0803552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.079668 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0681571 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0631009 |
| RPS6 | ribosomal protein S6 | -0.0617053 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0610395 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0602479 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.055039 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0510778 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0508295 |
| MT2A | metallothionein 2A | -0.0505106 |
| CD44 | CD44 molecule (Indian blood group) | -0.0498211 |
| HMGA2 | high mobility group AT-hook 2 | -0.0486178 |
| ACTG1 | actin gamma 1 | -0.0472721 |
| RPS8 | ribosomal protein S8 | -0.0442952 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0433614 |
| COL1A2 | collagen, type I, alpha 2 | -0.0412626 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0410717 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0404038 |
| GLIS3 | GLIS family zinc finger 3 | -0.0392494 |
| CALD1 | caldesmon 1 | -0.0389441 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0377483 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.037364 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0365815 |
| VCAN | versican | -0.0358008 |
| B2M | beta-2-microglobulin | -0.0351533 |
| FTL | ferritin, light polypeptide | -0.0337167 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0336244 |
| HLA-B | major histocompatibility complex, class I, B | -0.0329419 |
| CNTN5 | contactin 5 | -0.0327735 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0326636 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0326107 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0325472 |
| IL6ST | interleukin 6 signal transducer | -0.0325135 |
| RIGI | RNA sensor RIG-I | -0.0321332 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0312199 |
| S100A9 | S100 calcium binding protein A9 | -0.0308768 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0304907 |
| FBN1 | fibrillin 1 | -0.0300583 |
| TRAM1 | translocation associated membrane protein 1 | -0.029926 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.02969 |
| OSMR | oncostatin M receptor | -0.0296186 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0290709 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0276684 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0275969 |
| RPL35A | ribosomal protein L35a | -0.0264832 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0262565 |
| RND3 | Rho family GTPase 3 | -0.0260753 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0259449 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0257311 |
| RPL28 | ribosomal protein L28 | -0.0256175 |
| RPL8 | ribosomal protein L8 | -0.0255058 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0254609 |
| MTDH | metadherin | -0.0253118 |
| RPLP0 | ribosomal protein, large, P0 | -0.025295 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0252147 |
| RPS2 | ribosomal protein S2 | -0.0251593 |
| NREP | neuronal regeneration related protein | -0.025022 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0249223 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0246717 |
| AHR | aryl hydrocarbon receptor | -0.0243827 |
| RPS13 | ribosomal protein S13 | -0.0242343 |
| CLTC | clathrin, heavy chain (Hc) | -0.0241578 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0234126 |
| NRP1 | neuropilin 1 | -0.0233433 |
| EXOC4 | exocyst complex component 4 | -0.0232909 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0231981 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0230243 |
| RPS21 | ribosomal protein S21 | -0.0229854 |
| MT1X | metallothionein 1X | -0.0225463 |
| POTEF | POTE ankyrin domain family, member F | -0.0218501 |
| LDHA | lactate dehydrogenase A | -0.0216052 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0215712 |
| RPLP1 | ribosomal protein, large, P1 | -0.0215333 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0215274 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0211408 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0210462 |
| EHBP1 | EH domain binding protein 1 | -0.0209838 |
| MAP1B | microtubule-associated protein 1B | -0.020803 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0206827 |
| RPL26 | ribosomal protein L26 | -0.0205798 |
| CD99 | CD99 molecule | -0.0204266 |
| PKM | pyruvate kinase, muscle | -0.0204042 |
| PALLD | palladin, cytoskeletal associated protein | -0.0202948 |
| OXR1 | oxidation resistance 1 | -0.0201863 |
| ENO1 | enolase 1, (alpha) | -0.0201127 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0199819 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0194879 |
| RPL12 | ribosomal protein L12 | -0.0194841 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0192764 |
| TAPBP | TAP binding protein (tapasin) | -0.0192077 |
| DSTN | destrin (actin depolymerizing factor) | -0.0191754 |
| RPL9 | ribosomal protein L9 | -0.0189909 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0189251 |
| SEC24D | SEC24 family member D | -0.0188762 |
