| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0787949 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.077998 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0753134 |
| OGA | O-GlcNAcase | 0.0642439 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0611377 |
| PLEC | plectin | 0.0610374 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0584686 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0583752 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0558972 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0543462 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0543174 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0525853 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0510056 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0504742 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0495623 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0481149 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0481027 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0476486 |
| ARGLU1 | arginine and glutamate rich 1 | 0.046381 |
| AFDN | afadin, adherens junction formation factor | 0.0450682 |
| ACTN4 | actinin, alpha 4 | 0.0435407 |
| TMEM65 | transmembrane protein 65 | 0.041843 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0413478 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0392441 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0386981 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0370967 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0342875 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0340793 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0340406 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0339434 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0335435 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0335374 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0333357 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0333235 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0325274 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.031805 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314874 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314418 |
| EPS8L1 | EPS8-like 1 | 0.0313483 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0310612 |
| RPL19 | ribosomal protein L19 | 0.0305878 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0304992 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0297845 |
| FOXO3 | forkhead box O3 | 0.0297267 |
| CTBP2 | C-terminal binding protein 2 | 0.0296141 |
| TOP1 | topoisomerase (DNA) I | 0.0296068 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294132 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0290849 |
| PRELID2 | PRELI domain containing 2 | 0.0285652 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0284849 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0281767 |
| MCL1 | myeloid cell leukemia 1 | 0.0280294 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0279012 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.027814 |
| USP3 | ubiquitin specific peptidase 3 | 0.0277434 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0275127 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0275067 |
| MYO18A | myosin XVIIIA | 0.0271506 |
| NCKAP1 | NCK-associated protein 1 | 0.0269395 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0267571 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0266627 |
| FLNA | filamin A, alpha | 0.0266044 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0264704 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0263257 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263252 |
| HKDC1 | hexokinase domain containing 1 | 0.0262888 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260825 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0260721 |
| YTHDC1 | YTH domain containing 1 | 0.026002 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.025166 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0250864 |
| RPL3 | ribosomal protein L3 | 0.0250695 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0250149 |
| TUFT1 | tuftelin 1 | 0.0249446 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0248612 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.024799 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0247296 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0247294 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0245736 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0244694 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0243306 |
| USP12 | ubiquitin specific peptidase 12 | 0.0241691 |
| RNF145 | ring finger protein 145 | 0.0239976 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234005 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0232092 |
| VEGFA | vascular endothelial growth factor A | 0.0230878 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.022949 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0228277 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0228257 |
| SERINC1 | serine incorporator 1 | 0.0226245 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0226185 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0225645 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225559 |
| DIDO1 | death inducer-obliterator 1 | 0.0225486 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0224404 |
| STX3 | syntaxin 3 | 0.0222293 |
| RPL13A | ribosomal protein L13a | 0.0221981 |
| CASC3 | cancer susceptibility candidate 3 | 0.0220814 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0219806 |
| RBM33 | RNA binding motif protein 33 | 0.0219254 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.200319 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183582 |
| RPS6 | ribosomal protein S6 | -0.123535 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0924666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0841965 |
| EZR | ezrin | -0.0821614 |
| POTEF | POTE ankyrin domain family, member F | -0.0767608 |
| RPL23 | ribosomal protein L23 | -0.0688017 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0673218 |
| RPS8 | ribosomal protein S8 | -0.0652347 |
| RPLP1 | ribosomal protein, large, P1 | -0.0645147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.063042 |
| BPTF | bromodomain PHD finger transcription factor | -0.061898 |
| RPLP0 | ribosomal protein, large, P0 | -0.0592191 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0590055 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0586197 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0567792 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0551926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0543112 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0502539 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0501466 |
| S100A10 | S100 calcium binding protein A10 | -0.049666 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0491728 |
| LYZ | lysozyme | -0.0479891 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0472071 |
| RPS5 | ribosomal protein S5 | -0.0468881 |
| RPL12 | ribosomal protein L12 | -0.0463753 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0459235 |
| FBXO32 | F-box protein 32 | -0.0455077 |
| ACTG1 | actin gamma 1 | -0.0451256 |
| RPL8 | ribosomal protein L8 | -0.044767 |
| RPL28 | ribosomal protein L28 | -0.0430718 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0429346 |
| RPL18 | ribosomal protein L18 | -0.0426411 |
| CCNI | cyclin I | -0.0425884 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0421819 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0417894 |
| RPL35A | ribosomal protein L35a | -0.0405766 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0403607 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0402418 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0394212 |
| RPLP2 | ribosomal protein, large, P2 | -0.0388422 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0383862 |
| KRT20 | keratin 20, type I | -0.0381382 |
| RPS19 | ribosomal protein S19 | -0.0374374 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0372624 |
| RPS13 | ribosomal protein S13 | -0.0372018 |
| BCL2L1 | BCL2-like 1 | -0.0365821 |
| PERP | PERP, TP53 apoptosis effector | -0.0349887 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0349367 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0349015 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0347109 |
| RPS21 | ribosomal protein S21 | -0.0346334 |
| RPL27A | ribosomal protein L27a | -0.0341414 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338265 |
| RPS3 | ribosomal protein S3 | -0.0333554 |
| LATS2 | large tumor suppressor kinase 2 | -0.0330702 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0330158 |
| MYADM | myeloid-associated differentiation marker | -0.0328999 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0328102 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0326167 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0322674 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.032051 |
| TMSB10 | thymosin beta 10 | -0.0318271 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0316488 |
| HMGB1 | high mobility group box 1 | -0.031169 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0311356 |
| EGR1 | early growth response 1 | -0.0311246 |
| RPL9 | ribosomal protein L9 | -0.0301852 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301357 |
| EMP1 | epithelial membrane protein 1 | -0.0295965 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0293448 |
| POMP | proteasome maturation protein | -0.0293278 |
| GOLM2 | golgi membrane protein 2 | -0.0286245 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0284484 |
| NF1 | neurofibromin 1 | -0.02827 |
| MYO1E | myosin IE | -0.0282616 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0281862 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0280939 |
| FOSL1 | FOS-like antigen 1 | -0.0280473 |
| DEK | DEK proto-oncogene | -0.0279091 |
| RPS23 | ribosomal protein S23 | -0.0276826 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272985 |
| RPS16 | ribosomal protein S16 | -0.0272555 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272472 |
| RPL34 | ribosomal protein L34 | -0.0271417 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0268255 |
| DSTN | destrin (actin depolymerizing factor) | -0.0267972 |
| PKM | pyruvate kinase, muscle | -0.0267888 |
| GPX2 | glutathione peroxidase 2 | -0.0267652 |
| FOXP1 | forkhead box P1 | -0.0266035 |
| S100A9 | S100 calcium binding protein A9 | -0.0264403 |
| RPL11 | ribosomal protein L11 | -0.0262777 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259626 |
| NBEAL1 | neurobeachin-like 1 | -0.0254519 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0254227 |
| PFN1 | profilin 1 | -0.0252418 |
| CBX3 | chromobox homolog 3 | -0.0251093 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0251088 |
| WWC1 | WW and C2 domain containing 1 | -0.0250511 |
