| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.130868 |
| PLEC | plectin | 0.123017 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.107031 |
| MYOF | myoferlin | 0.0927577 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0843951 |
| MTSS1 | metastasis suppressor 1 | 0.0822247 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0786359 |
| SMAD3 | SMAD family member 3 | 0.0771073 |
| MEF2A | myocyte enhancer factor 2A | 0.0697635 |
| KIAA1217 | KIAA1217 | 0.0634283 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0631696 |
| MSN | moesin | 0.0595999 |
| FOXO1 | forkhead box O1 | 0.0537309 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0531194 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0522412 |
| FLNA | filamin A, alpha | 0.0485244 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0478815 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.045659 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0451053 |
| OGA | O-GlcNAcase | 0.0444746 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0444018 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0441043 |
| ACTN4 | actinin, alpha 4 | 0.0438251 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0437523 |
| AHNAK | AHNAK nucleoprotein | 0.0433672 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0429624 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0426944 |
| PDLIM1 | PDZ and LIM domain 1 | 0.042581 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0416918 |
| PTK2 | protein tyrosine kinase 2 | 0.0412663 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0397178 |
| PRELID2 | PRELI domain containing 2 | 0.0396166 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0394649 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0394102 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0385688 |
| NAV2 | neuron navigator 2 | 0.0381627 |
| MYO10 | myosin X | 0.037886 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367758 |
| NEK7 | NIMA-related kinase 7 | 0.0365109 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0353469 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0352405 |
| RIN2 | Ras and Rab interactor 2 | 0.0347105 |
| BCL2L1 | BCL2-like 1 | 0.0344307 |
| SBF2 | SET binding factor 2 | 0.0341779 |
| ASPH | aspartate beta-hydroxylase | 0.0341393 |
| CUL4B | cullin 4B | 0.034101 |
| ANLN | anillin, actin binding protein | 0.0339585 |
| SEPTIN9 | septin 9 | 0.0325635 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0325229 |
| CD44 | CD44 molecule (Indian blood group) | 0.0323454 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0320566 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0319224 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0310083 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0308587 |
| LOXL2 | lysyl oxidase-like 2 | 0.0306579 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0305482 |
| AFAP1 | actin filament associated protein 1 | 0.0302065 |
| VCL | vinculin | 0.0300954 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.030081 |
| ZNF292 | zinc finger protein 292 | 0.0300725 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0299504 |
| MCL1 | myeloid cell leukemia 1 | 0.0298339 |
| AOPEP | aminopeptidase O (putative) | 0.0297775 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.029763 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0296227 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0295862 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0289013 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0288224 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0283791 |
| PLAT | plasminogen activator, tissue | 0.0276849 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0275647 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0268332 |
| ARRDC3 | arrestin domain containing 3 | 0.0266913 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0266066 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0265155 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0262061 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0260208 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0257855 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0253787 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0253783 |
| H1-0 | H1.0 linker histone | 0.0252183 |
| SPAG9 | sperm associated antigen 9 | 0.0251418 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0251261 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0251168 |
| FOXP1 | forkhead box P1 | 0.0250925 |
| BLCAP | bladder cancer associated protein | 0.0246331 |
| TGM2 | transglutaminase 2 | 0.0246185 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0244339 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0243157 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0242359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0239743 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0238284 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0233235 |
| RBM39 | RNA binding motif protein 39 | 0.0232376 |
| DIDO1 | death inducer-obliterator 1 | 0.0232102 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0230468 |
| MED13L | mediator complex subunit 13-like | 0.022956 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0229338 |
| CAPRIN2 | caprin family member 2 | 0.02282 |
| ANXA11 | annexin A11 | 0.0227594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.146519 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.100255 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0958658 |
| PTMA | prothymosin, alpha | -0.070563 |
| MT2A | metallothionein 2A | -0.0690505 |
| RPS6 | ribosomal protein S6 | -0.0614469 |
| TMSB10 | thymosin beta 10 | -0.0605558 |
| B2M | beta-2-microglobulin | -0.0599252 |
| HLA-B | major histocompatibility complex, class I, B | -0.0518615 |
| RPS8 | ribosomal protein S8 | -0.047854 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0465447 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0462142 |
| RPLP2 | ribosomal protein, large, P2 | -0.0453478 |
| RPLP1 | ribosomal protein, large, P1 | -0.0446034 |
| S100A10 | S100 calcium binding protein A10 | -0.0418771 |
| RPS13 | ribosomal protein S13 | -0.0415583 |
| IGF2 | insulin-like growth factor 2 | -0.0409862 |
| RPS3 | ribosomal protein S3 | -0.0406024 |
| FTL | ferritin, light polypeptide | -0.0405178 |
| RPS21 | ribosomal protein S21 | -0.0404668 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0379697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0361663 |
| RPL37 | ribosomal protein L37 | -0.0360479 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357554 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0355619 |
| RPS19 | ribosomal protein S19 | -0.0355117 |
| LDHA | lactate dehydrogenase A | -0.034822 |
| INTS6 | integrator complex subunit 6 | -0.0338409 |
| RPL35A | ribosomal protein L35a | -0.0331154 |
| S100A11 | S100 calcium binding protein A11 | -0.033059 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0322793 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0320435 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0318838 |
| DPYD | dihydropyrimidine dehydrogenase | -0.030575 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0305329 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0299897 |
| S100A9 | S100 calcium binding protein A9 | -0.0299402 |
| GNAS | GNAS complex locus | -0.0298617 |
| RPL37A | ribosomal protein L37a | -0.0295212 |
| HM13 | histocompatibility (minor) 13 | -0.0292463 |
| RPL8 | ribosomal protein L8 | -0.0291633 |
| S100A6 | S100 calcium binding protein A6 | -0.0288306 |
| RPL34 | ribosomal protein L34 | -0.0280549 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0278877 |
| RPS25 | ribosomal protein S25 | -0.0278367 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0273726 |
| CSTB | cystatin B (stefin B) | -0.0267093 |
| EGR1 | early growth response 1 | -0.0267062 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0260248 |
| RPL12 | ribosomal protein L12 | -0.026 |
| POTEF | POTE ankyrin domain family, member F | -0.0255177 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.025212 |
| RACK1 | receptor for activated C kinase 1 | -0.0243319 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0240407 |
| WASF2 | WAS protein family, member 2 | -0.023866 |
| PFN1 | profilin 1 | -0.0236697 |
| SQLE | squalene epoxidase | -0.0235672 |
| ACTG1 | actin gamma 1 | -0.0235488 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0231592 |
| RPL7A | ribosomal protein L7a | -0.0231115 |
| RPL9 | ribosomal protein L9 | -0.0230503 |
| S100A2 | S100 calcium binding protein A2 | -0.0229951 |
| MTDH | metadherin | -0.0227321 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0227124 |
| RPS24 | ribosomal protein S24 | -0.0226468 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0224005 |
| RPL11 | ribosomal protein L11 | -0.0221891 |
| ANXA1 | annexin A1 | -0.0220477 |
| RPS29 | ribosomal protein S29 | -0.0219734 |
| MT1X | metallothionein 1X | -0.0215284 |
| RPS14 | ribosomal protein S14 | -0.0215013 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207857 |
| RPS12 | ribosomal protein S12 | -0.0207738 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205728 |
| THBD | thrombomodulin | -0.0205197 |
| RPS27A | ribosomal protein S27a | -0.0201378 |
| RPL26 | ribosomal protein L26 | -0.0199688 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0199615 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0199116 |
| RPL27A | ribosomal protein L27a | -0.0197786 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0196759 |
| RPL31 | ribosomal protein L31 | -0.0196586 |
| RPL23 | ribosomal protein L23 | -0.0195812 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0193949 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0191826 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0186819 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0186618 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0185183 |
| RPL28 | ribosomal protein L28 | -0.0183484 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0182627 |
| MYADM | myeloid-associated differentiation marker | -0.018169 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0181205 |
| MORF4L2 | mortality factor 4 like 2 | -0.018056 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0179446 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0179037 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.017893 |
| MT1E | metallothionein 1E | -0.0178453 |
| KISS1 | KiSS-1 metastasis-suppressor | -0.0177529 |
| CAV2 | caveolin 2 | -0.0176108 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0175834 |