| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0629203 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0612078 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0559737 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0379276 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0350495 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0345641 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0340711 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0315717 |
| FLNA | filamin A, alpha | 0.0308016 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0307095 |
| ATP13A3 | ATPase type 13A3 | 0.0300359 |
| SMAD3 | SMAD family member 3 | 0.0269381 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.022262 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0212856 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0209183 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0203735 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0199475 |
| GPR107 | G protein-coupled receptor 107 | 0.0197356 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0197045 |
| ZNF841 | zinc finger protein 841 | 0.0194697 |
| ARF4 | ADP-ribosylation factor 4 | 0.0191873 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0190732 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0185703 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0182747 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0181296 |
| CLTC | clathrin, heavy chain (Hc) | 0.0180598 |
| HLA-C | major histocompatibility complex, class I, C | 0.0174043 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0173031 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 0.0171735 |
| ARRDC3 | arrestin domain containing 3 | 0.0166607 |
| SCFD2 | sec1 family domain containing 2 | 0.0164824 |
| NUP153 | nucleoporin 153kDa | 0.016289 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0161647 |
| TMEM39A | transmembrane protein 39A | 0.0160815 |
| GOLGA3 | golgin A3 | 0.0156317 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0155364 |
| TFG | TRK-fused gene | 0.0151036 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0150878 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0149476 |
| NAV2 | neuron navigator 2 | 0.0149409 |
| FLNB | filamin B, beta | 0.0147964 |
| PLEC | plectin | 0.0147281 |
| UBQLN1 | ubiquilin 1 | 0.0146726 |
| SUCO | SUN domain containing ossification factor | 0.0144934 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0144532 |
| RLIM | ring finger protein, LIM domain interacting | 0.014323 |
| ACTN4 | actinin, alpha 4 | 0.0139176 |
| BCL2L1 | BCL2-like 1 | 0.0135729 |
| UBC | ubiquitin C | 0.0133984 |
| SEPTIN9 | septin 9 | 0.0133898 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0133471 |
| BLCAP | bladder cancer associated protein | 0.0130628 |
| IL6ST | interleukin 6 signal transducer | 0.0129609 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0129514 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0129087 |
| CORO1C | coronin, actin binding protein, 1C | 0.01289 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0128502 |
| CUL4B | cullin 4B | 0.0128414 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0126149 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0123906 |
| COL5A1 | collagen, type V, alpha 1 | 0.0122281 |
| DIDO1 | death inducer-obliterator 1 | 0.0121278 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0121091 |
| GOLGA2 | golgin A2 | 0.012052 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0119944 |
| RUNX2 | runt-related transcription factor 2 | 0.0119555 |
| ANKRD36 | ankyrin repeat domain 36 | 0.011932 |
| OSMR | oncostatin M receptor | 0.0119287 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0119269 |
| ODF2 | outer dense fiber of sperm tails 2 | 0.011877 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0117677 |
| PLPP3 | phospholipid phosphatase 3 | 0.0117664 |
| XPO6 | exportin 6 | 0.0116302 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0116106 |
| FAT1 | FAT atypical cadherin 1 | 0.0114976 |
| MB21D2 | Mab-21 domain containing 2 | 0.0114732 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 0.0113442 |
| CEP192 | centrosomal protein 192kDa | 0.0111194 |
| PMM2 | phosphomannomutase 2 | 0.0110361 |
| NUP214 | nucleoporin 214kDa | 0.0110192 |
| COG6 | component of oligomeric golgi complex 6 | 0.0109072 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0108128 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0107476 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0107423 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.010721 |
| NUP98 | nucleoporin 98kDa | 0.0107008 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0106904 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0106458 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0105955 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0105583 |
| RANBP9 | RAN binding protein 9 | 0.01052 |
| YME1L1 | YME1-like 1 ATPase | 0.0105089 |
| H1-4 | H1.4 linker histone, cluster member | 0.0104911 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0104708 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0104093 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0102845 |
| GCN1 | GCN1 activator of EIF2AK4 | 0.0102843 |
| LOXL2 | lysyl oxidase-like 2 | 0.0102705 |
| SPAG9 | sperm associated antigen 9 | 0.010269 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0101864 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.120507 |
| FTL | ferritin, light polypeptide | -0.10722 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.100323 |
| HLA-B | major histocompatibility complex, class I, B | -0.0895072 |
| MT2A | metallothionein 2A | -0.0891403 |
| FN1 | fibronectin 1 | -0.0835241 |
| NDRG1 | N-myc downstream regulated 1 | -0.072928 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0642137 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0615791 |
| DEK | DEK proto-oncogene | -0.0608924 |
| RPS6 | ribosomal protein S6 | -0.0592245 |
| POTEF | POTE ankyrin domain family, member F | -0.0568354 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0540617 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0483664 |
| VIM | vimentin | -0.0452665 |
| ANXA2 | annexin A2 | -0.0430617 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0427486 |
| ACTG1 | actin gamma 1 | -0.0424317 |
| RPL35A | ribosomal protein L35a | -0.0393143 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0392637 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0376366 |
| LDHA | lactate dehydrogenase A | -0.0370282 |
| TMSB10 | thymosin beta 10 | -0.0367256 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.035162 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0346146 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0339732 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0331684 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0319141 |
| DTNA | dystrobrevin, alpha | -0.0318162 |
| RPS8 | ribosomal protein S8 | -0.031357 |
| PTMA | prothymosin, alpha | -0.0308547 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0304505 |
| PFN1 | profilin 1 | -0.0290754 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.028898 |
| SET | SET nuclear proto-oncogene | -0.0287428 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0283153 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0278369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0274512 |
| PKM | pyruvate kinase, muscle | -0.0271046 |
| ASPH | aspartate beta-hydroxylase | -0.027079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0264855 |
| ENO1 | enolase 1, (alpha) | -0.0262905 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0257942 |
| HMGB1 | high mobility group box 1 | -0.0257899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.025429 |
| RPLP2 | ribosomal protein, large, P2 | -0.025331 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0248882 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0243979 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0238957 |
| RPL12 | ribosomal protein L12 | -0.0233896 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0233775 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0231198 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0231116 |
| B2M | beta-2-microglobulin | -0.0223835 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0223652 |
| TPM1 | tropomyosin 1 (alpha) | -0.0214852 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0214564 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0212896 |
| CCDC80 | coiled-coil domain containing 80 | -0.0212378 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0210516 |
| RPS3 | ribosomal protein S3 | -0.021005 |
| MMP12 | matrix metallopeptidase 12 | -0.0209584 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0202295 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.020196 |
| GNAS | GNAS complex locus | -0.0199485 |
| VEGFA | vascular endothelial growth factor A | -0.0199358 |
| CCND1 | cyclin D1 | -0.0198796 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0198668 |
| RPL5 | ribosomal protein L5 | -0.0196949 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0195616 |
| S100A6 | S100 calcium binding protein A6 | -0.0191274 |
| TPM4 | tropomyosin 4 | -0.0189551 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0189014 |
| RAI14 | retinoic acid induced 14 | -0.0188924 |
| LMNA | lamin A/C | -0.0188287 |
| NAV1 | neuron navigator 1 | -0.0186947 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0183739 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0182139 |
| MAP1B | microtubule-associated protein 1B | -0.0180662 |
| RND3 | Rho family GTPase 3 | -0.0179715 |
| RPL23 | ribosomal protein L23 | -0.0179709 |
| CAVIN1 | caveolae associated protein 1 | -0.0179364 |
| RPS13 | ribosomal protein S13 | -0.0178999 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0178638 |
| KRT7 | keratin 7, type II | -0.0177234 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0176826 |
| DST | dystonin | -0.0175764 |
| FOSL1 | FOS-like antigen 1 | -0.0174676 |
| ANXA1 | annexin A1 | -0.0174643 |
| YBX1 | Y box binding protein 1 | -0.0174424 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0173648 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0172016 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.01702 |
| RPL11 | ribosomal protein L11 | -0.0169848 |
| RACK1 | receptor for activated C kinase 1 | -0.0168763 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0168177 |
| CENPF | centromere protein F, 350/400kDa | -0.0166919 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0166097 |
| RPS19 | ribosomal protein S19 | -0.0165751 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0164437 |
