| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.158419 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.154028 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.131532 |
| HYOU1 | hypoxia up-regulated 1 | 0.0906621 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0860387 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0850269 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0755761 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0745749 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0702628 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0688142 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0649391 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0648009 |
| PLEC | plectin | 0.0638481 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0625111 |
| FLNB | filamin B, beta | 0.0598017 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0597863 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0585294 |
| AHNAK | AHNAK nucleoprotein | 0.0559307 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0548759 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0544763 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0544191 |
| TES | testin LIM domain protein | 0.0536295 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0513908 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0506827 |
| ACTN4 | actinin, alpha 4 | 0.050125 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0495424 |
| ATXN1 | ataxin 1 | 0.0492108 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0483419 |
| FAT1 | FAT atypical cadherin 1 | 0.0481139 |
| ZNF292 | zinc finger protein 292 | 0.0479143 |
| SPAG9 | sperm associated antigen 9 | 0.0476225 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0475037 |
| NDRG1 | N-myc downstream regulated 1 | 0.0469409 |
| DSPP | dentin sialophosphoprotein | 0.0463825 |
| ANLN | anillin, actin binding protein | 0.0449024 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.04396 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0434876 |
| OGA | O-GlcNAcase | 0.0431281 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0428747 |
| TMSB4X | thymosin beta 4, X-linked | 0.0411046 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0407133 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0405868 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0404655 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0403496 |
| CLTC | clathrin, heavy chain (Hc) | 0.0400095 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.039884 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0398646 |
| FAM13A | family with sequence similarity 13, member A | 0.0396797 |
| MUC17 | mucin 17, cell surface associated | 0.0395892 |
| RBM39 | RNA binding motif protein 39 | 0.0394942 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0390321 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0386257 |
| XPO1 | exportin 1 | 0.0377009 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0376978 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0376799 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0376595 |
| ANXA11 | annexin A11 | 0.0374194 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0367824 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0364408 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.036237 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0361991 |
| CANX | calnexin | 0.0353182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348261 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0346955 |
| KRT18 | keratin 18, type I | 0.0340052 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0339998 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0339849 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0338768 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0338403 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.033625 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0329142 |
| TRIM2 | tripartite motif containing 2 | 0.0326995 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0326581 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0326422 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0323819 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0323567 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0322601 |
| H1-0 | H1.0 linker histone | 0.0318898 |
| CCNY | cyclin Y | 0.03152 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0313397 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0312149 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0310833 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0308941 |
| KLHL29 | kelch-like family member 29 | 0.030493 |
| COG5 | component of oligomeric golgi complex 5 | 0.0304829 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0301505 |
| ARCN1 | archain 1 | 0.0301356 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0299628 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0298618 |
| LAMB3 | laminin, beta 3 | 0.0297941 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0297331 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0297252 |
| HELZ | helicase with zinc finger | 0.0294527 |
| NEK6 | NIMA-related kinase 6 | 0.0294319 |
| MEF2A | myocyte enhancer factor 2A | 0.0292615 |
| ARF4 | ADP-ribosylation factor 4 | 0.0291263 |
| GOLGA4 | golgin A4 | 0.0289195 |
| SEPTIN9 | septin 9 | 0.0288302 |
| AFDN | afadin, adherens junction formation factor | 0.0286087 |
| TPD52 | tumor protein D52 | 0.0285619 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.111369 |
| TMSB10 | thymosin beta 10 | -0.0916596 |
| NPSR1 | neuropeptide S receptor 1 | -0.0800916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0751526 |
| FTL | ferritin, light polypeptide | -0.0634742 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0613604 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0546283 |
| RPS6 | ribosomal protein S6 | -0.0513865 |
| B2M | beta-2-microglobulin | -0.0503136 |
| PTMA | prothymosin, alpha | -0.0488787 |
| RPL35A | ribosomal protein L35a | -0.0475371 |
| TMC5 | transmembrane channel-like 5 | -0.0466748 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0432303 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0431926 |
| RPS3 | ribosomal protein S3 | -0.0423572 |
| EHBP1 | EH domain binding protein 1 | -0.0389802 |
| S100A6 | S100 calcium binding protein A6 | -0.0375405 |
| RPLP1 | ribosomal protein, large, P1 | -0.036677 |
| POTEF | POTE ankyrin domain family, member F | -0.0356243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.032852 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0317217 |
| RPL23 | ribosomal protein L23 | -0.0315363 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0312345 |
| S100A10 | S100 calcium binding protein A10 | -0.0311153 |
| S100A11 | S100 calcium binding protein A11 | -0.0304712 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0302375 |
| PKM | pyruvate kinase, muscle | -0.0297209 |
| CDK6 | cyclin-dependent kinase 6 | -0.0277991 |
| S100P | S100 calcium binding protein P | -0.0274226 |
| CLDN4 | claudin 4 | -0.0271749 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0271389 |
| RPL28 | ribosomal protein L28 | -0.027065 |
| GPX2 | glutathione peroxidase 2 | -0.0267302 |
| ACTG1 | actin gamma 1 | -0.026188 |
| TFF2 | trefoil factor 2 | -0.0261122 |
| S100A9 | S100 calcium binding protein A9 | -0.0252619 |
| RPS8 | ribosomal protein S8 | -0.0251191 |
| MUC1 | mucin 1, cell surface associated | -0.024986 |
| RPS19 | ribosomal protein S19 | -0.0248267 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0239364 |
| PFN1 | profilin 1 | -0.0238704 |
| POF1B | premature ovarian failure, 1B | -0.0236644 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0228917 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0223796 |
| PHF14 | PHD finger protein 14 | -0.0223323 |
| EMP1 | epithelial membrane protein 1 | -0.0218081 |
| RPL34 | ribosomal protein L34 | -0.0217928 |
| RPL37A | ribosomal protein L37a | -0.0214839 |
| CST3 | cystatin C | -0.0214109 |
| RPS10 | ribosomal protein S10 | -0.0213871 |
| RPL18 | ribosomal protein L18 | -0.0213639 |
| RPS27A | ribosomal protein S27a | -0.0213519 |
| AGR2 | anterior gradient 2 | -0.0211516 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0210797 |
| RPS12 | ribosomal protein S12 | -0.0210196 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0206156 |
| LCN2 | lipocalin 2 | -0.0204636 |
| RPL9 | ribosomal protein L9 | -0.0204046 |
| HMGB1 | high mobility group box 1 | -0.0199265 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0198206 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0197362 |
| RPS21 | ribosomal protein S21 | -0.0195865 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0195851 |
| RPL8 | ribosomal protein L8 | -0.0193033 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0189916 |
| EPCAM | epithelial cell adhesion molecule | -0.0189794 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0189445 |
| RPS16 | ribosomal protein S16 | -0.0188702 |
| RPS24 | ribosomal protein S24 | -0.0187516 |
| HLA-B | major histocompatibility complex, class I, B | -0.0186841 |
| RPLP2 | ribosomal protein, large, P2 | -0.0185333 |
| FOXQ1 | forkhead box Q1 | -0.0184061 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0179819 |
| SERF2 | small EDRK-rich factor 2 | -0.0177808 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0175071 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0174956 |
| INTS6 | integrator complex subunit 6 | -0.0173549 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.017246 |
| MT2A | metallothionein 2A | -0.0172038 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0171251 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0170734 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0168474 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0167262 |
| RPL30 | ribosomal protein L30 | -0.0165169 |
| RPL7A | ribosomal protein L7a | -0.0162195 |
| PERP | PERP, TP53 apoptosis effector | -0.0161225 |
| DSTN | destrin (actin depolymerizing factor) | -0.0160853 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0159753 |
| RPS29 | ribosomal protein S29 | -0.0155962 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0155533 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0155408 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.015445 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0154361 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0154053 |
| ASTN2 | astrotactin 2 | -0.0154025 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0153974 |
| TTYH3 | tweety family member 3 | -0.0153359 |
| RPL26 | ribosomal protein L26 | -0.0152782 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0149328 |
| HLA-A | major histocompatibility complex, class I, A | -0.0148397 |
