| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.202548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.104079 |
| NDRG1 | N-myc downstream regulated 1 | 0.104061 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102218 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0995682 |
| EREG | epiregulin | 0.0894429 |
| GOLGA4 | golgin A4 | 0.0887584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0870913 |
| DSCAM | Down syndrome cell adhesion molecule | 0.085032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0832396 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0804293 |
| FAM13A | family with sequence similarity 13, member A | 0.0789764 |
| FAT1 | FAT atypical cadherin 1 | 0.0787081 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0753378 |
| TXNIP | thioredoxin interacting protein | 0.0748086 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0682465 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0679673 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0676292 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0635551 |
| RNF145 | ring finger protein 145 | 0.0622572 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0620919 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0609981 |
| FLNB | filamin B, beta | 0.0584534 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0568028 |
| MED13L | mediator complex subunit 13-like | 0.055955 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0551404 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0517726 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0515282 |
| CALR | calreticulin | 0.0508912 |
| RNF43 | ring finger protein 43 | 0.0502241 |
| PRELID2 | PRELI domain containing 2 | 0.050184 |
| WAC | WW domain containing adaptor with coiled-coil | 0.049279 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0477973 |
| OGA | O-GlcNAcase | 0.0472818 |
| ZNF292 | zinc finger protein 292 | 0.0471962 |
| ACTN4 | actinin, alpha 4 | 0.0468835 |
| LMO7 | LIM domain 7 | 0.0463845 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.046031 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0459617 |
| LDHA | lactate dehydrogenase A | 0.0453443 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0450239 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0449421 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0448818 |
| TNS4 | tensin 4 | 0.0448376 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0446528 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0444723 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0444204 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0443027 |
| CCNY | cyclin Y | 0.0441526 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0437909 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0435722 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0433211 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0428001 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0423563 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0422854 |
| PTEN | phosphatase and tensin homolog | 0.0421144 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0412235 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0411529 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0410789 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0407064 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405214 |
| DSPP | dentin sialophosphoprotein | 0.0404131 |
| RBM39 | RNA binding motif protein 39 | 0.0403639 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0402495 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.039921 |
| PIGR | polymeric immunoglobulin receptor | 0.039487 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.039428 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0391078 |
| TRIM2 | tripartite motif containing 2 | 0.0388222 |
| PCBP2 | poly(rC) binding protein 2 | 0.0382018 |
| NEBL | nebulette | 0.0380801 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0378766 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0377928 |
| KRT18 | keratin 18, type I | 0.0367296 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0367125 |
| SETD5 | SET domain containing 5 | 0.0362093 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0361141 |
| TFG | TRK-fused gene | 0.0357173 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0353435 |
| ENO1 | enolase 1, (alpha) | 0.035331 |
| HDLBP | high density lipoprotein binding protein | 0.035279 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0351818 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0350433 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0348698 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.034744 |
| CTBP2 | C-terminal binding protein 2 | 0.0345905 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0344443 |
| ATXN1 | ataxin 1 | 0.0343947 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0343584 |
| COPA | coatomer protein complex, subunit alpha | 0.0343011 |
| NEK7 | NIMA-related kinase 7 | 0.0342343 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0338631 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0338178 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0336256 |
| NBAS | neuroblastoma amplified sequence | 0.0334795 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0333677 |
| HELZ | helicase with zinc finger | 0.033181 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.03306 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0329519 |
| VEGFA | vascular endothelial growth factor A | 0.0329082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.17124 |
| NPSR1 | neuropeptide S receptor 1 | -0.136245 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0980182 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.093521 |
| TMSB10 | thymosin beta 10 | -0.0727625 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0679537 |
| ONECUT3 | one cut homeobox 3 | -0.0640249 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0625492 |
| MT2A | metallothionein 2A | -0.06194 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0614035 |
| RPS6 | ribosomal protein S6 | -0.0521755 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0475179 |
| ACTG1 | actin gamma 1 | -0.0460362 |
| AHNAK | AHNAK nucleoprotein | -0.0450252 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0422754 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0393287 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0377367 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0365454 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0312625 |
| EHBP1 | EH domain binding protein 1 | -0.0302451 |
| MT1E | metallothionein 1E | -0.0293918 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0290326 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.028429 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0273274 |
| RNF217 | ring finger protein 217 | -0.0272243 |
| TPM4 | tropomyosin 4 | -0.0269295 |
| FTL | ferritin, light polypeptide | -0.0257982 |
| HMGB1 | high mobility group box 1 | -0.0248336 |
| MT1X | metallothionein 1X | -0.02461 |
| S100A6 | S100 calcium binding protein A6 | -0.0243884 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.023923 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0238789 |
| MYO1E | myosin IE | -0.0237508 |
| CLOCK | clock circadian regulator | -0.0215539 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0213709 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0213449 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0211388 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0210482 |
| RPS19 | ribosomal protein S19 | -0.0209611 |
| IER3 | immediate early response 3 | -0.0206073 |
| MTAP | methylthioadenosine phosphorylase | -0.0205358 |
| MECOM | MDS1 and EVI1 complex locus | -0.0203456 |
| RIN2 | Ras and Rab interactor 2 | -0.0201445 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.02006 |
| SVIL | supervillin | -0.0193054 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0192237 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0187109 |
| RPLP1 | ribosomal protein, large, P1 | -0.0184436 |
| DIAPH2 | diaphanous-related formin 2 | -0.0184318 |
| LAMA4 | laminin, alpha 4 | -0.0181517 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0180573 |
| TFF1 | trefoil factor 1 | -0.0179128 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0177477 |
| CCDC91 | coiled-coil domain containing 91 | -0.0176786 |
| SRPK1 | SRSF protein kinase 1 | -0.0175554 |
| FERMT1 | fermitin family member 1 | -0.0174007 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0173975 |
| HMGA2 | high mobility group AT-hook 2 | -0.0172271 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0171601 |
| CALB1 | calbindin 1, 28kDa | -0.0169176 |
| NRN1 | neuritin 1 | -0.0166823 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0166118 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0163287 |
| LSAMP | limbic system-associated membrane protein | -0.0163276 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0159061 |
| DEK | DEK proto-oncogene | -0.0155917 |
| EPHB2 | EPH receptor B2 | -0.0155141 |
| VCAN | versican | -0.0154921 |
| AHI1 | Abelson helper integration site 1 | -0.0154651 |
| CRACD | capping protein inhibiting regulator of actin dynamics | -0.015451 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0151449 |
| CSTB | cystatin B (stefin B) | -0.0150813 |
| PRDX2 | peroxiredoxin 2 | -0.0150759 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0150323 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0148024 |
| ABR | active BCR-related | -0.0143593 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0143381 |
| CNKSR3 | CNKSR family member 3 | -0.0142143 |
| RPS27A | ribosomal protein S27a | -0.0139875 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0139255 |
| WLS | wntless Wnt ligand secretion mediator | -0.0138712 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0138671 |
| EZR | ezrin | -0.0138591 |
| PKP4 | plakophilin 4 | -0.0137208 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0136469 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0135424 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0134605 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0134257 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0134161 |
| INSR | insulin receptor | -0.0134002 |
| NBEAL1 | neurobeachin-like 1 | -0.0133374 |
| LMNA | lamin A/C | -0.0133087 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0132859 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0132694 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.013268 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0132217 |
| SH3D19 | SH3 domain containing 19 | -0.0131785 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.013173 |
| CUX1 | cut-like homeobox 1 | -0.0131607 |
| CCND1 | cyclin D1 | -0.0131595 |
