| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.13119 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.102612 |
| FLNB | filamin B, beta | 0.0845353 |
| FAT1 | FAT atypical cadherin 1 | 0.0777528 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0669921 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0667113 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0614635 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0606325 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0604925 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0579718 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0574734 |
| GOLGA4 | golgin A4 | 0.0551773 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0533095 |
| RPL4 | ribosomal protein L4 | 0.0516872 |
| OGA | O-GlcNAcase | 0.0496978 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0482169 |
| ACTN4 | actinin, alpha 4 | 0.0468599 |
| RPL3 | ribosomal protein L3 | 0.0464323 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.045557 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0452704 |
| DSPP | dentin sialophosphoprotein | 0.0446944 |
| CANX | calnexin | 0.0442219 |
| FOXO1 | forkhead box O1 | 0.0441062 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0432956 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0417579 |
| MYO6 | myosin VI | 0.0414718 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0414708 |
| LMO7 | LIM domain 7 | 0.0402158 |
| HDLBP | high density lipoprotein binding protein | 0.0394867 |
| MED13L | mediator complex subunit 13-like | 0.0394335 |
| ANKRD11 | ankyrin repeat domain 11 | 0.039236 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0388662 |
| PRELID2 | PRELI domain containing 2 | 0.0384523 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0373419 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0368341 |
| LAMB3 | laminin, beta 3 | 0.036549 |
| EREG | epiregulin | 0.0361886 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0358377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0358245 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0350681 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0347673 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0343857 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0334542 |
| SMAD3 | SMAD family member 3 | 0.0324438 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0323787 |
| CCPG1 | cell cycle progression 1 | 0.0322935 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0319916 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0315053 |
| USP3 | ubiquitin specific peptidase 3 | 0.0312657 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0312383 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0312109 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0311013 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0309757 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0309005 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0307421 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0307082 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0304487 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.030277 |
| RPL19 | ribosomal protein L19 | 0.0301184 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0299112 |
| LRRC1 | leucine rich repeat containing 1 | 0.0296838 |
| ATXN1 | ataxin 1 | 0.0295584 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.029474 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.029302 |
| YME1L1 | YME1-like 1 ATPase | 0.0290711 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0290193 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0286444 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0283159 |
| CDC42SE2 | CDC42 small effector 2 | 0.0279301 |
| AFDN | afadin, adherens junction formation factor | 0.0276146 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.027501 |
| ZNF292 | zinc finger protein 292 | 0.0274702 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0271996 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0271729 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0271674 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271551 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0270788 |
| PTEN | phosphatase and tensin homolog | 0.0270574 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.026666 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0261787 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0260752 |
| COG5 | component of oligomeric golgi complex 5 | 0.0260751 |
| RNF145 | ring finger protein 145 | 0.0257923 |
| CORO1C | coronin, actin binding protein, 1C | 0.025706 |
| NCKAP1 | NCK-associated protein 1 | 0.0256589 |
| EPHA2 | EPH receptor A2 | 0.0256434 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0255422 |
| CDK19 | cyclin-dependent kinase 19 | 0.0255176 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0253395 |
| ABHD17C | abhydrolase domain containing 17C | 0.0253168 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0252965 |
| ETNK1 | ethanolamine kinase 1 | 0.0252884 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0245692 |
| SHROOM3 | shroom family member 3 | 0.0244004 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0243057 |
| SUCO | SUN domain containing ossification factor | 0.0242215 |
| POU2F1 | POU class 2 homeobox 1 | 0.0241964 |
| GOLGA3 | golgin A3 | 0.0240139 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0239787 |
| RPL7 | ribosomal protein L7 | 0.0239284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.171701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170236 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.109573 |
| RPLP1 | ribosomal protein, large, P1 | -0.0980522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0848509 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.076869 |
| RPLP0 | ribosomal protein, large, P0 | -0.0749029 |
| POTEF | POTE ankyrin domain family, member F | -0.073128 |
| ACTG1 | actin gamma 1 | -0.0721152 |
| RPS8 | ribosomal protein S8 | -0.0713091 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0658346 |
| TMSB10 | thymosin beta 10 | -0.0581591 |
| RPS19 | ribosomal protein S19 | -0.05651 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0541012 |
| RPL35A | ribosomal protein L35a | -0.0536071 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0525972 |
| PTMA | prothymosin, alpha | -0.0505056 |
| RPLP2 | ribosomal protein, large, P2 | -0.0504681 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0447677 |
| RPS13 | ribosomal protein S13 | -0.043954 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0435017 |
| RPL34 | ribosomal protein L34 | -0.0429758 |
| RPL31 | ribosomal protein L31 | -0.0418941 |
| RPL23 | ribosomal protein L23 | -0.040315 |
| HLA-B | major histocompatibility complex, class I, B | -0.0393851 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.039153 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0390338 |
| RACK1 | receptor for activated C kinase 1 | -0.0389019 |
| PKM | pyruvate kinase, muscle | -0.0378313 |
| RPL28 | ribosomal protein L28 | -0.0369576 |
| RPS23 | ribosomal protein S23 | -0.0366439 |
| RPL9 | ribosomal protein L9 | -0.0365517 |
| EGR1 | early growth response 1 | -0.0360747 |
| SP100 | SP100 nuclear antigen | -0.0360471 |
| RPL8 | ribosomal protein L8 | -0.0360359 |
| MX1 | MX dynamin-like GTPase 1 | -0.0360037 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.035318 |
| MT2A | metallothionein 2A | -0.0351294 |
| RPS14 | ribosomal protein S14 | -0.0348443 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0341885 |
| RPL32 | ribosomal protein L32 | -0.0339619 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0333455 |
| S100A10 | S100 calcium binding protein A10 | -0.0324146 |
| S100A9 | S100 calcium binding protein A9 | -0.0318199 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.031217 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0310207 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0300667 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0298227 |
| RPL12 | ribosomal protein L12 | -0.0293828 |
| PFN1 | profilin 1 | -0.0290991 |
| FOXP1 | forkhead box P1 | -0.0285133 |
| CLDN4 | claudin 4 | -0.0282915 |
| RPS5 | ribosomal protein S5 | -0.0280505 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0276525 |
| RBM25 | RNA binding motif protein 25 | -0.0275911 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0275496 |
| PERP | PERP, TP53 apoptosis effector | -0.0271921 |
| RPS3 | ribosomal protein S3 | -0.0263539 |
| RPL37A | ribosomal protein L37a | -0.0261944 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0260816 |
| RPS24 | ribosomal protein S24 | -0.0259918 |
| RPS29 | ribosomal protein S29 | -0.0257747 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0256327 |
| RPS27A | ribosomal protein S27a | -0.0254872 |
| RPS15 | ribosomal protein S15 | -0.0252316 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0251086 |
| RPS21 | ribosomal protein S21 | -0.025008 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0248278 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0248274 |
| DIAPH2 | diaphanous-related formin 2 | -0.0248001 |
| RPL36 | ribosomal protein L36 | -0.0245692 |
| ENO1 | enolase 1, (alpha) | -0.024318 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0242001 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0238806 |
| RPL18 | ribosomal protein L18 | -0.0234983 |
| WWOX | WW domain containing oxidoreductase | -0.0229897 |
| RPS16 | ribosomal protein S16 | -0.0226964 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0226699 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0226684 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0224267 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0222108 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0217182 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0216763 |
| DEK | DEK proto-oncogene | -0.0216166 |
| INTS6 | integrator complex subunit 6 | -0.0216154 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0215863 |
| RPS11 | ribosomal protein S11 | -0.0215858 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0214975 |
| JUN | jun proto-oncogene | -0.0214824 |
| FTL | ferritin, light polypeptide | -0.0214087 |
| NPSR1 | neuropeptide S receptor 1 | -0.0211513 |
| RPL27A | ribosomal protein L27a | -0.0211347 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208992 |
| S100A6 | S100 calcium binding protein A6 | -0.0208458 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0208186 |
| TBCA | tubulin folding cofactor A | -0.0208044 |
| RIGI | RNA sensor RIG-I | -0.0207865 |
| RPL38 | ribosomal protein L38 | -0.0204909 |
| MX2 | MX dynamin-like GTPase 2 | -0.0204299 |
| FHIT | fragile histidine triad | -0.0204146 |
