| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.322012 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.159192 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.12289 |
| MCL1 | myeloid cell leukemia 1 | 0.122745 |
| NDRG1 | N-myc downstream regulated 1 | 0.110813 |
| ARRDC3 | arrestin domain containing 3 | 0.102022 |
| CES1 | carboxylesterase 1 | 0.0907527 |
| SMAD3 | SMAD family member 3 | 0.0879274 |
| PLEC | plectin | 0.0839503 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0825448 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0814779 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0763624 |
| FAM13A | family with sequence similarity 13, member A | 0.0731833 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0718012 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0703585 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0699815 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0697281 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0693382 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0678224 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0672368 |
| SPAG9 | sperm associated antigen 9 | 0.0641803 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0641079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0616966 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0602867 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0598575 |
| MSN | moesin | 0.0591074 |
| HYOU1 | hypoxia up-regulated 1 | 0.0578773 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.056645 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.056001 |
| PYGL | phosphorylase, glycogen, liver | 0.0559533 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.055435 |
| ATP13A3 | ATPase type 13A3 | 0.0552218 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0539908 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0533831 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0528092 |
| HELZ | helicase with zinc finger | 0.0518773 |
| RNF145 | ring finger protein 145 | 0.0512607 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0483563 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0483534 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0475535 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0467484 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0465605 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0465425 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0464449 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0450665 |
| RPL7 | ribosomal protein L7 | 0.0447232 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0446844 |
| DSPP | dentin sialophosphoprotein | 0.0440825 |
| TOP1 | topoisomerase (DNA) I | 0.0432585 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0429017 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.042648 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0424846 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0421855 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0421843 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0418844 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0416625 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0413968 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.040893 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.040862 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0407938 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0405634 |
| RUNX1 | runt-related transcription factor 1 | 0.0405063 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0404896 |
| PTMA | prothymosin, alpha | 0.0404629 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0402678 |
| MKI67 | marker of proliferation Ki-67 | 0.0402205 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0400514 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0398681 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0396011 |
| NCKAP1 | NCK-associated protein 1 | 0.03896 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0388447 |
| RPL19 | ribosomal protein L19 | 0.0387542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0386775 |
| SETD5 | SET domain containing 5 | 0.0384891 |
| KRT18 | keratin 18, type I | 0.038205 |
| ENO1 | enolase 1, (alpha) | 0.0381971 |
| TFG | TRK-fused gene | 0.0375695 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0370387 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.036679 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0365204 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0364885 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0359037 |
| PUM2 | pumilio RNA-binding family member 2 | 0.035731 |
| PDE8A | phosphodiesterase 8A | 0.0353473 |
| MED13L | mediator complex subunit 13-like | 0.0352285 |
| UBC | ubiquitin C | 0.0351918 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.034995 |
| NUP58 | nucleoporin 58 | 0.0346511 |
| TPD52 | tumor protein D52 | 0.0343934 |
| UVRAG | UV radiation resistance associated | 0.0342946 |
| PTK2 | protein tyrosine kinase 2 | 0.0339568 |
| LAMB3 | laminin, beta 3 | 0.0337706 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0336893 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0330267 |
| NPTN | neuroplastin | 0.0329556 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0328795 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0325608 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0323645 |
| RPL3 | ribosomal protein L3 | 0.0321365 |
| TPM3 | tropomyosin 3 | 0.0317073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.156803 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119679 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0585389 |
| OSMR | oncostatin M receptor | -0.0549062 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0539801 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0515497 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0491345 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0480438 |
| EGR1 | early growth response 1 | -0.0479857 |
| MT2A | metallothionein 2A | -0.0432659 |
| EFNA5 | ephrin-A5 | -0.0430682 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0428562 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0384408 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0376181 |
| GM2A | GM2 ganglioside activator | -0.0343646 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0331494 |
| RPS24 | ribosomal protein S24 | -0.0325027 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0321814 |
| NABP1 | nucleic acid binding protein 1 | -0.0313455 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0311057 |
| TRIM56 | tripartite motif containing 56 | -0.0305414 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0298913 |
| AHNAK | AHNAK nucleoprotein | -0.0290083 |
| SMIM14 | small integral membrane protein 14 | -0.0273826 |
| HLA-B | major histocompatibility complex, class I, B | -0.0265373 |
| RPL34 | ribosomal protein L34 | -0.0262344 |
| PATJ | PATJ crumbs cell polarity complex component | -0.026227 |
| FRMD4B | FERM domain containing 4B | -0.0261403 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.025762 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0252936 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0251486 |
| AGR2 | anterior gradient 2 | -0.0241724 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.024103 |
| MORF4L2 | mortality factor 4 like 2 | -0.0240579 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.024023 |
| CANX | calnexin | -0.0238018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0233413 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0225723 |
| CCND1 | cyclin D1 | -0.0224594 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0222828 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0220751 |
| TMSB10 | thymosin beta 10 | -0.0220185 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0220173 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0218193 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0217424 |
| MT1X | metallothionein 1X | -0.0216448 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0215799 |
| RPL35A | ribosomal protein L35a | -0.0214294 |
| RIGI | RNA sensor RIG-I | -0.021079 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0210585 |
| MGAT4C | MGAT4 family, member C | -0.0210116 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0209714 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0208332 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0203837 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0202139 |
| TUT4 | terminal uridylyl transferase 4 | -0.0201874 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0201049 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0198611 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0197726 |
| ACTG1 | actin gamma 1 | -0.0197281 |
| SEC61G | Sec61 gamma subunit | -0.0195251 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0195026 |
| RNF169 | ring finger protein 169 | -0.0190842 |
| ASPH | aspartate beta-hydroxylase | -0.0189281 |
| NBEAL1 | neurobeachin-like 1 | -0.0188891 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0186668 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.018631 |
| BPTF | bromodomain PHD finger transcription factor | -0.0180396 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0178518 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0177723 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0177076 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0176298 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0176286 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0176036 |
| SEC24D | SEC24 family member D | -0.0173988 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0173964 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0173793 |
| H1-0 | H1.0 linker histone | -0.017337 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0169835 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0166597 |
| RPLP1 | ribosomal protein, large, P1 | -0.0166393 |
| CCNI | cyclin I | -0.0164527 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0163939 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0160748 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0160702 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0160175 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0157342 |
| S100A9 | S100 calcium binding protein A9 | -0.0157198 |
| SP100 | SP100 nuclear antigen | -0.0150402 |
| HM13 | histocompatibility (minor) 13 | -0.0150168 |
| EMP1 | epithelial membrane protein 1 | -0.0149779 |
| SHTN1 | shootin 1 | -0.0148442 |
| NPC1 | Niemann-Pick disease, type C1 | -0.014778 |
| RPS21 | ribosomal protein S21 | -0.0147512 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0144976 |
| ATG12 | autophagy related 12 | -0.0144854 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0143582 |
| SDC4 | syndecan 4 | -0.0142813 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0140022 |
| FOXP1 | forkhead box P1 | -0.0139392 |
