| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.163899 |
| FNDC3B | fibronectin type III domain containing 3B | 0.138198 |
| SMAD3 | SMAD family member 3 | 0.12691 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.116546 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0896659 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0827501 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0791614 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0786506 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0776062 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0775998 |
| PCBP2 | poly(rC) binding protein 2 | 0.0761895 |
| ATP13A3 | ATPase type 13A3 | 0.0748712 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0699273 |
| NAV2 | neuron navigator 2 | 0.0676132 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0655233 |
| FAM13A | family with sequence similarity 13, member A | 0.0636022 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0635696 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0598555 |
| OGA | O-GlcNAcase | 0.0587335 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.058395 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.058331 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0575068 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0571907 |
| SPAG9 | sperm associated antigen 9 | 0.0553231 |
| FLNB | filamin B, beta | 0.0531834 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0519046 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0493147 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0469409 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0467011 |
| HELZ | helicase with zinc finger | 0.0462014 |
| RUNX1 | runt-related transcription factor 1 | 0.0460878 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0448435 |
| USP3 | ubiquitin specific peptidase 3 | 0.0447216 |
| SIK3 | SIK family kinase 3 | 0.0441722 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0435682 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0430022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.042885 |
| PFKP | phosphofructokinase, platelet | 0.0425613 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0425152 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0423904 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0418173 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0411709 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0403215 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0401998 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.039664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0392916 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0392761 |
| PTK2 | protein tyrosine kinase 2 | 0.0392578 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0392122 |
| LOXL2 | lysyl oxidase-like 2 | 0.0387406 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0378324 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.037492 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0374704 |
| APP | amyloid beta (A4) precursor protein | 0.0374693 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0371546 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0358844 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0355178 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.033773 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0332007 |
| MYO10 | myosin X | 0.0331913 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0329368 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0325233 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.031863 |
| FMNL2 | formin-like 2 | 0.03167 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0315261 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0313037 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0312778 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0309838 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0309157 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308165 |
| SETD5 | SET domain containing 5 | 0.0308024 |
| CTNNBL1 | catenin, beta like 1 | 0.0307439 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0299076 |
| NBAS | neuroblastoma amplified sequence | 0.0298912 |
| RUNX2 | runt-related transcription factor 2 | 0.0298523 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0297832 |
| PDE8A | phosphodiesterase 8A | 0.0296504 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0293973 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0292094 |
| TGM2 | transglutaminase 2 | 0.0291898 |
| NGLY1 | N-glycanase 1 | 0.02889 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0288673 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0288378 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0284532 |
| AHR | aryl hydrocarbon receptor | 0.0278249 |
| RNF145 | ring finger protein 145 | 0.0276671 |
| RBM39 | RNA binding motif protein 39 | 0.0276062 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0271562 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0270309 |
| MSN | moesin | 0.0269224 |
| MYO1B | myosin IB | 0.026883 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0268482 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0267662 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0266263 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0265935 |
| RBM33 | RNA binding motif protein 33 | 0.026557 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0264458 |
| NEK7 | NIMA-related kinase 7 | 0.0262857 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0262493 |
| VEGFA | vascular endothelial growth factor A | 0.0261964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150039 |
| VIM | vimentin | -0.135676 |
| TMSB10 | thymosin beta 10 | -0.116788 |
| LOX | lysyl oxidase | -0.115747 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104002 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0888153 |
| FTL | ferritin, light polypeptide | -0.0885144 |
| HMGA2 | high mobility group AT-hook 2 | -0.0678506 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0546321 |
| RPS19 | ribosomal protein S19 | -0.0526087 |
| SYT1 | synaptotagmin I | -0.0517809 |
| GLCCI1 | glucocorticoid induced 1 | -0.0499182 |
| MT2A | metallothionein 2A | -0.0497843 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0479275 |
| PTMA | prothymosin, alpha | -0.0476061 |
| FN1 | fibronectin 1 | -0.0456388 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0451544 |
| RPLP1 | ribosomal protein, large, P1 | -0.0432878 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0425368 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0422759 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0418785 |
| NTN4 | netrin 4 | -0.041161 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0402421 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0380314 |
| EGR1 | early growth response 1 | -0.0373455 |
| S100A6 | S100 calcium binding protein A6 | -0.0370942 |
| IER3 | immediate early response 3 | -0.0368271 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0354223 |
| RAD51B | RAD51 paralog B | -0.0349238 |
| NRG1 | neuregulin 1 | -0.0345361 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.03453 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0343677 |
| MAP1B | microtubule-associated protein 1B | -0.0342433 |
| CDH13 | cadherin 13 | -0.0339814 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.033797 |
| BPTF | bromodomain PHD finger transcription factor | -0.0337288 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0336564 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0333198 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0333027 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0329346 |
| MYO9A | myosin IXA | -0.0327858 |
| ZNF804A | zinc finger protein 804A | -0.0326842 |
| RPS6 | ribosomal protein S6 | -0.0319855 |
| DST | dystonin | -0.0313954 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0305959 |
| CANX | calnexin | -0.0305084 |
| STC1 | stanniocalcin 1 | -0.0302541 |
| RPS8 | ribosomal protein S8 | -0.030027 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0298385 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.029821 |
| RPLP2 | ribosomal protein, large, P2 | -0.0295925 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0295486 |
| EHBP1 | EH domain binding protein 1 | -0.0293294 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.029088 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0290649 |
| RPL35A | ribosomal protein L35a | -0.0286395 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0286329 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0285325 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0281018 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0279992 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0279605 |
| MECOM | MDS1 and EVI1 complex locus | -0.0277649 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276547 |
| TGFB1 | transforming growth factor, beta 1 | -0.0272463 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0270427 |
| ARF4 | ADP-ribosylation factor 4 | -0.0269319 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0265194 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0259727 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0257995 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0254504 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0253273 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251441 |
| RASAL2 | RAS protein activator like 2 | -0.0247822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0245713 |
| MYADM | myeloid-associated differentiation marker | -0.024542 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0245139 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0244081 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0241212 |
| RPL34 | ribosomal protein L34 | -0.0239759 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0237977 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0234251 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0233301 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0232612 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.02312 |
| ZNF609 | zinc finger protein 609 | -0.0227876 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0225342 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0221956 |
| PFN1 | profilin 1 | -0.0221311 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217806 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0217125 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0214482 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0214433 |
| RAI14 | retinoic acid induced 14 | -0.0214001 |
| HLA-B | major histocompatibility complex, class I, B | -0.0213752 |
| SUMF1 | sulfatase modifying factor 1 | -0.0212946 |
| AADAC | arylacetamide deacetylase | -0.0211724 |
| ATF4 | activating transcription factor 4 | -0.0210892 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0210807 |
| VCL | vinculin | -0.0209394 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0208755 |
