| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | 0.128592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119082 |
| RBM39 | RNA binding motif protein 39 | 0.11865 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.115161 |
| FAM13A | family with sequence similarity 13, member A | 0.102361 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0999054 |
| ZNF292 | zinc finger protein 292 | 0.0975491 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0909857 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0907554 |
| PTK2 | protein tyrosine kinase 2 | 0.0842583 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0809233 |
| EGFR | epidermal growth factor receptor | 0.0793685 |
| RNF145 | ring finger protein 145 | 0.0765848 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0762022 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0755589 |
| FN1 | fibronectin 1 | 0.0730925 |
| YTHDC1 | YTH domain containing 1 | 0.0711537 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0701712 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0680103 |
| RORA | RAR-related orphan receptor A | 0.0665239 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0661635 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.066108 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0660202 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0653426 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0652115 |
| INHBA | inhibin, beta A | 0.0651593 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0640709 |
| FAT1 | FAT atypical cadherin 1 | 0.0640453 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0624176 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0606103 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0601341 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.059046 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0578094 |
| RIOK3 | RIO kinase 3 | 0.0562744 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0558576 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0557073 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0551173 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0550483 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0532328 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0528693 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0523428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0520669 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0506046 |
| ANXA5 | annexin A5 | 0.049698 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0486376 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0483761 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0478887 |
| PTEN | phosphatase and tensin homolog | 0.0474383 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.047039 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0464839 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0459485 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0450548 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0442435 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0442015 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0441831 |
| RLF | rearranged L-myc fusion | 0.0439723 |
| RTN4 | reticulon 4 | 0.0435651 |
| CCNY | cyclin Y | 0.0433068 |
| FOXJ3 | forkhead box J3 | 0.0428901 |
| RND3 | Rho family GTPase 3 | 0.0425676 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0420798 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0413346 |
| ADAR | adenosine deaminase, RNA-specific | 0.0410072 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0405278 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.039965 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0399511 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0397286 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0396852 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0393756 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0391835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0389192 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0388812 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0387433 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0379362 |
| RIGI | RNA sensor RIG-I | 0.0379018 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0372128 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0367924 |
| SCFD1 | sec1 family domain containing 1 | 0.0366434 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.036024 |
| JMJD1C | jumonji domain containing 1C | 0.0360106 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0360009 |
| MED13L | mediator complex subunit 13-like | 0.0351488 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0343913 |
| LSAMP | limbic system-associated membrane protein | 0.0337685 |
| PRKCA | protein kinase C, alpha | 0.0336438 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0336252 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0330844 |
| NUP58 | nucleoporin 58 | 0.0324046 |
| TPD52 | tumor protein D52 | 0.0321542 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0320623 |
| PDE10A | phosphodiesterase 10A | 0.0317394 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0315849 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0312237 |
| MSI2 | musashi RNA-binding protein 2 | 0.031217 |
| XPO1 | exportin 1 | 0.0311628 |
| NAV2 | neuron navigator 2 | 0.0310369 |
| TPR | translocated promoter region, nuclear basket protein | 0.0308262 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0305772 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0302596 |
| RBM25 | RNA binding motif protein 25 | 0.0296381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.14609 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.134319 |
| ATOSA | atos homolog A | -0.130373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109345 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0966507 |
| AHNAK | AHNAK nucleoprotein | -0.0959508 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0915032 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0902016 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0900507 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0799825 |
| FTL | ferritin, light polypeptide | -0.0783717 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0781392 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.076843 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0747958 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.072515 |
| B2M | beta-2-microglobulin | -0.0701179 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0678607 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0655673 |
| FOXO3 | forkhead box O3 | -0.0651428 |
| LAMC2 | laminin, gamma 2 | -0.0619356 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.060848 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0605692 |
| LMO7 | LIM domain 7 | -0.0604782 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0575995 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0571515 |
| MYO1E | myosin IE | -0.0571286 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0551772 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0544272 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0542723 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0537391 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0532735 |
| S100A9 | S100 calcium binding protein A9 | -0.0524757 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0522613 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0520188 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0518319 |
| OSMR | oncostatin M receptor | -0.0516855 |
| ABHD17C | abhydrolase domain containing 17C | -0.0514116 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0509684 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0506544 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0503718 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0495462 |
| LAMB3 | laminin, beta 3 | -0.0493327 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0492348 |
| UBC | ubiquitin C | -0.0491959 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0469933 |
| TXNRD1 | thioredoxin reductase 1 | -0.0462381 |
| HLA-B | major histocompatibility complex, class I, B | -0.0460586 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0458225 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0455586 |
| KRT17 | keratin 17, type I | -0.0454983 |
| USP53 | ubiquitin specific peptidase 53 | -0.045478 |
| RPLP1 | ribosomal protein, large, P1 | -0.0454253 |
| RREB1 | ras responsive element binding protein 1 | -0.0446553 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0444083 |
| CCNI | cyclin I | -0.044211 |
| PTMA | prothymosin, alpha | -0.0437385 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0429704 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0429316 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0428524 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0425446 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0419809 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0410925 |
| PKM | pyruvate kinase, muscle | -0.0410748 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0410006 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0409732 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0404678 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0393575 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.039049 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0389323 |
| CEP350 | centrosomal protein 350kDa | -0.0387687 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0387033 |
| PERP | PERP, TP53 apoptosis effector | -0.0385759 |
| RPL26 | ribosomal protein L26 | -0.0385015 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.038402 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0383451 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0380395 |
| KIAA1217 | KIAA1217 | -0.0375618 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0374108 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0372027 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0369965 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0369564 |
| SEC24D | SEC24 family member D | -0.0368092 |
| SQSTM1 | sequestosome 1 | -0.0361012 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360427 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0357597 |
| MYOF | myoferlin | -0.0352893 |
| RAI14 | retinoic acid induced 14 | -0.0343034 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0342791 |
| TANK | TRAF family member-associated NFKB activator | -0.0342674 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0339282 |
| MCL1 | myeloid cell leukemia 1 | -0.033802 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0336578 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0335618 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0325488 |
| RPL19 | ribosomal protein L19 | -0.0325295 |
| NBEA | neurobeachin | -0.0323893 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0323297 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0322275 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.031662 |
| RAB10 | RAB10, member RAS oncogene family | -0.0309039 |
