| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.129145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120942 |
| OGA | O-GlcNAcase | 0.0768516 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0712423 |
| RAD51B | RAD51 paralog B | 0.0703669 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0701068 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0682355 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0654356 |
| KRT18 | keratin 18, type I | 0.0555258 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0553312 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0553042 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0531482 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0526319 |
| PLEC | plectin | 0.0517312 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0516637 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0503953 |
| ATXN1 | ataxin 1 | 0.0476606 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0461874 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0461659 |
| TPM3 | tropomyosin 3 | 0.0461457 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0460767 |
| SMAD3 | SMAD family member 3 | 0.0459746 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0455432 |
| PGK1 | phosphoglycerate kinase 1 | 0.0443747 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0432065 |
| BBX | bobby sox homolog (Drosophila) | 0.0429156 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0415402 |
| CEP192 | centrosomal protein 192kDa | 0.0413851 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0405451 |
| ZNF292 | zinc finger protein 292 | 0.0403108 |
| ENO1 | enolase 1, (alpha) | 0.0403079 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0402289 |
| PRELID2 | PRELI domain containing 2 | 0.0402004 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0376445 |
| APP | amyloid beta (A4) precursor protein | 0.0369142 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0368341 |
| CEP250 | centrosomal protein 250kDa | 0.0365326 |
| UBC | ubiquitin C | 0.0360037 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0356701 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356488 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0354863 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0351494 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.035044 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0346877 |
| CTTN | cortactin | 0.0343908 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0338785 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0334867 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0332996 |
| SPAG9 | sperm associated antigen 9 | 0.0331638 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0329416 |
| ADAR | adenosine deaminase, RNA-specific | 0.0323646 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0323281 |
| MCL1 | myeloid cell leukemia 1 | 0.0314635 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304169 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0303855 |
| LOXL2 | lysyl oxidase-like 2 | 0.0298874 |
| UBQLN1 | ubiquilin 1 | 0.0295546 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0293689 |
| AHNAK | AHNAK nucleoprotein | 0.0292377 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.02891 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0286384 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0286274 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0285481 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0284299 |
| SP3 | Sp3 transcription factor | 0.0283271 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0283148 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0282694 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0279008 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0276905 |
| PRKCE | protein kinase C, epsilon | 0.0276345 |
| PFKP | phosphofructokinase, platelet | 0.0272889 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270031 |
| FMNL2 | formin-like 2 | 0.0267069 |
| PREPL | prolyl endopeptidase-like | 0.0265911 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0265195 |
| PTMA | prothymosin, alpha | 0.0264937 |
| ANLN | anillin, actin binding protein | 0.026213 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.025908 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0257175 |
| MKI67 | marker of proliferation Ki-67 | 0.0257158 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0256185 |
| NCKAP1 | NCK-associated protein 1 | 0.0254833 |
| PHIP | pleckstrin homology domain interacting protein | 0.0251409 |
| RLIM | ring finger protein, LIM domain interacting | 0.0250743 |
| FLNA | filamin A, alpha | 0.0250333 |
| CANX | calnexin | 0.0249967 |
| PYGL | phosphorylase, glycogen, liver | 0.0249587 |
| SRPK1 | SRSF protein kinase 1 | 0.024943 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248642 |
| TRIM33 | tripartite motif containing 33 | 0.0248231 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0246279 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0245146 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0244569 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0243817 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0242314 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0241914 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0239822 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0237826 |
| FAM168A | family with sequence similarity 168, member A | 0.0236456 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0234063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.120415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0944475 |
| POTEF | POTE ankyrin domain family, member F | -0.071036 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0632909 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0585244 |
| ACTG1 | actin gamma 1 | -0.0523588 |
| NABP1 | nucleic acid binding protein 1 | -0.052234 |
| PFN1 | profilin 1 | -0.049273 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0436739 |
| TXNRD1 | thioredoxin reductase 1 | -0.0423548 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0371222 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0357102 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0342047 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0312265 |
| YBX3 | Y box binding protein 3 | -0.0272264 |
| THOC2 | THO complex 2 | -0.0270592 |
| OSMR | oncostatin M receptor | -0.0267152 |
| RPS8 | ribosomal protein S8 | -0.0263019 |
| GPHN | gephyrin | -0.0260319 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0256422 |
| ZNF644 | zinc finger protein 644 | -0.0251821 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250974 |
| RAB7A | RAB7A, member RAS oncogene family | -0.024778 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.024598 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0243203 |
| CALD1 | caldesmon 1 | -0.0243011 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0240041 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0239642 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0233116 |
| MT2A | metallothionein 2A | -0.0232684 |
| RPS6 | ribosomal protein S6 | -0.0226838 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0225833 |
| RASAL2 | RAS protein activator like 2 | -0.0223359 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.021646 |
| RPS3 | ribosomal protein S3 | -0.0213279 |
| VCL | vinculin | -0.0213034 |
| INTS6 | integrator complex subunit 6 | -0.0210899 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0208864 |
| MYPN | myopalladin | -0.0208623 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0207552 |
| PMP22 | peripheral myelin protein 22 | -0.0205475 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0205089 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0201183 |
| LATS2 | large tumor suppressor kinase 2 | -0.0199612 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0197929 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0191761 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0190632 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0190354 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0190098 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0189764 |
| NRG1 | neuregulin 1 | -0.0188076 |
| RBM25 | RNA binding motif protein 25 | -0.018639 |
| FTL | ferritin, light polypeptide | -0.0185374 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0184858 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0184546 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0180086 |
| RPL5 | ribosomal protein L5 | -0.0179567 |
| VMP1 | vacuole membrane protein 1 | -0.0179338 |
| RPL36 | ribosomal protein L36 | -0.0178141 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.0177481 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0176246 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0174788 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0174501 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0174088 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0172002 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0171715 |
| ARMH4 | armadillo like helical domain containing 4 | -0.016934 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.0169241 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0167312 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0166711 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0166244 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0163489 |
| WDR43 | WD repeat domain 43 | -0.015897 |
| BPTF | bromodomain PHD finger transcription factor | -0.0158464 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0157326 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0157103 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0156845 |
| RPL28 | ribosomal protein L28 | -0.015649 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0154927 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0154817 |
| RPS15 | ribosomal protein S15 | -0.0153152 |
| RPS19 | ribosomal protein S19 | -0.0151711 |
| RPL8 | ribosomal protein L8 | -0.014942 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0148325 |
| LDHB | lactate dehydrogenase B | -0.0148221 |
| RACK1 | receptor for activated C kinase 1 | -0.0148132 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0146504 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0143487 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0142703 |
| CEP112 | centrosomal protein 112kDa | -0.0139497 |
| KDSR | 3-ketodihydrosphingosine reductase | -0.013808 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0137296 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0136691 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0136618 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0136348 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0135677 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0134411 |
| PLCB4 | phospholipase C, beta 4 | -0.0133777 |
| RPS21 | ribosomal protein S21 | -0.0131754 |
| RPL27 | ribosomal protein L27 | -0.0131123 |
