| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.18508 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.126481 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.108537 |
| DST | dystonin | 0.105819 |
| THBS1 | thrombospondin 1 | 0.0875514 |
| TMSB4X | thymosin beta 4, X-linked | 0.0866672 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0787301 |
| PEG10 | paternally expressed 10 | 0.0735253 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0666693 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0660624 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0637317 |
| ACTN4 | actinin, alpha 4 | 0.0585238 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0570182 |
| ENAH | enabled homolog (Drosophila) | 0.0567957 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0550308 |
| ITGAV | integrin, alpha V | 0.0544816 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0510099 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.050935 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0495638 |
| XPO1 | exportin 1 | 0.0494329 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0484099 |
| MYO10 | myosin X | 0.0480897 |
| ANXA1 | annexin A1 | 0.0479486 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0477531 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.046413 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0447236 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0441068 |
| FLNA | filamin A, alpha | 0.0439047 |
| CANX | calnexin | 0.0437734 |
| PRTG | protogenin | 0.0433116 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0432763 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0430528 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0429738 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0420003 |
| APP | amyloid beta (A4) precursor protein | 0.0415255 |
| UBQLN1 | ubiquilin 1 | 0.0407359 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0406086 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0405246 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0398092 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0391394 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0387295 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0383358 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0380101 |
| EMP1 | epithelial membrane protein 1 | 0.0379402 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0378073 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0373906 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0370821 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0368945 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0368694 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0365334 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0360872 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0360306 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0355882 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0353922 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0353383 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0344782 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0342754 |
| ZNF292 | zinc finger protein 292 | 0.0340566 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0338662 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0337845 |
| COL5A2 | collagen, type V, alpha 2 | 0.0336574 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0335045 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.033499 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.033174 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0328358 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0327642 |
| CORO1C | coronin, actin binding protein, 1C | 0.0327454 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0325949 |
| SHROOM3 | shroom family member 3 | 0.0324347 |
| OLA1 | Obg-like ATPase 1 | 0.032182 |
| H1-4 | H1.4 linker histone, cluster member | 0.0319585 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031943 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0319141 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0318665 |
| RBM33 | RNA binding motif protein 33 | 0.0317213 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0315233 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0311818 |
| FMNL2 | formin-like 2 | 0.0309658 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0308421 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | 0.0308294 |
| RPL3 | ribosomal protein L3 | 0.0307484 |
| PRELID2 | PRELI domain containing 2 | 0.0306305 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.030521 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0301257 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0300497 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0297582 |
| LYPLA1 | lysophospholipase I | 0.0296183 |
| HELZ | helicase with zinc finger | 0.0294801 |
| RTN4 | reticulon 4 | 0.0294246 |
| MTF2 | metal response element binding transcription factor 2 | 0.0292544 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0291096 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0289256 |
| RBM39 | RNA binding motif protein 39 | 0.0288477 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0288215 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.028678 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0284685 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0281627 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0280517 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.027993 |
| PGRMC1 | progesterone receptor membrane component 1 | 0.0278042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.162764 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.128091 |
| TMSB10 | thymosin beta 10 | -0.0753978 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0737523 |
| PCDH9 | protocadherin 9 | -0.0525561 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0523577 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0518822 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0475814 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0471369 |
| MEIS2 | Meis homeobox 2 | -0.0445151 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0438221 |
| B2M | beta-2-microglobulin | -0.0425178 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0403325 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0401214 |
| SPAG9 | sperm associated antigen 9 | -0.039653 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0374147 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0370743 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0369263 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0363763 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.035089 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0349713 |
| CADM2 | cell adhesion molecule 2 | -0.0344141 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0336303 |
| RPS6 | ribosomal protein S6 | -0.0329602 |
| SNX6 | sorting nexin 6 | -0.0306919 |
| SRP54 | signal recognition particle 54kDa | -0.030639 |
| RPL35A | ribosomal protein L35a | -0.030455 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0297227 |
| RPLP1 | ribosomal protein, large, P1 | -0.029714 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0290114 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0288972 |
| HDAC9 | histone deacetylase 9 | -0.0276405 |
| TMEM165 | transmembrane protein 165 | -0.0275235 |
| FTL | ferritin, light polypeptide | -0.0272288 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0272103 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0269073 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0268108 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0260481 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0256228 |
| VMP1 | vacuole membrane protein 1 | -0.0255925 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.025522 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0252822 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0250306 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0248675 |
| LRRC4C | leucine rich repeat containing 4C | -0.0239001 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0235941 |
| TOX | thymocyte selection-associated high mobility group box | -0.022986 |
| PHIP | pleckstrin homology domain interacting protein | -0.0228383 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0227875 |
| TENM2 | teneurin transmembrane protein 2 | -0.0223812 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0221994 |
| NHSL1 | NHS-like 1 | -0.0221882 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0220571 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0220316 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0218338 |
| LPIN2 | lipin 2 | -0.0218063 |
| RPS13 | ribosomal protein S13 | -0.0215928 |
| CCN2 | cellular communication network factor 2 | -0.0215329 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0213047 |
| EXOC1 | exocyst complex component 1 | -0.0212863 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0212599 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0211932 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.020907 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0208187 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0205981 |
| RPS24 | ribosomal protein S24 | -0.0204334 |
| CDC27 | cell division cycle 27 | -0.0204299 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0203793 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0202344 |
| LATS2 | large tumor suppressor kinase 2 | -0.02017 |
| RIGI | RNA sensor RIG-I | -0.0200344 |
| RPL37A | ribosomal protein L37a | -0.019846 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.019771 |
| GPATCH8 | G patch domain containing 8 | -0.0197039 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0195842 |
| RPS16 | ribosomal protein S16 | -0.019532 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0195006 |
| TENT4B | terminal nucleotidyltransferase 4B | -0.0194387 |
| APOE | apolipoprotein E | -0.0193043 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0191921 |
| UBXN4 | UBX domain protein 4 | -0.0191451 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0188501 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.0187878 |
| RAD51B | RAD51 paralog B | -0.0186838 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.018663 |
| KLHL5 | kelch-like family member 5 | -0.0185119 |
| RBM20 | RNA binding motif protein 20 | -0.0182429 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0182197 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0181576 |
| LNPK | lunapark, ER junction formation factor | -0.0181116 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0179997 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0177393 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.017669 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0176679 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0176608 |
| EPN2 | epsin 2 | -0.0176277 |
| MYO9A | myosin IXA | -0.0175022 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0174968 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0174912 |
| INSR | insulin receptor | -0.017402 |
