| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.159702 |
| ACTN4 | actinin, alpha 4 | 0.154962 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.131582 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.127638 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.127561 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.127529 |
| SEPTIN9 | septin 9 | 0.124222 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.10589 |
| FNDC3B | fibronectin type III domain containing 3B | 0.103744 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0981364 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0924477 |
| SMAD3 | SMAD family member 3 | 0.0885717 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0836406 |
| NAV2 | neuron navigator 2 | 0.0797017 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0715773 |
| SPAG9 | sperm associated antigen 9 | 0.0702252 |
| DST | dystonin | 0.068606 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0676815 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0612012 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0607262 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0602762 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0598729 |
| ANLN | anillin, actin binding protein | 0.0584471 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0562289 |
| MSN | moesin | 0.0548759 |
| PLEC | plectin | 0.0545595 |
| ZFP36 | ZFP36 ring finger protein | 0.0532783 |
| PCBP2 | poly(rC) binding protein 2 | 0.0488225 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0486543 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.048534 |
| MYOF | myoferlin | 0.0478302 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0475642 |
| LDHA | lactate dehydrogenase A | 0.047206 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0468937 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0468421 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0465857 |
| TPM3 | tropomyosin 3 | 0.0455565 |
| MCL1 | myeloid cell leukemia 1 | 0.0448726 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0423849 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0423683 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0423079 |
| EGFR | epidermal growth factor receptor | 0.0412452 |
| L1CAM | L1 cell adhesion molecule | 0.0409847 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0408247 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0406013 |
| XPO1 | exportin 1 | 0.0395686 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0395035 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0393832 |
| PDE10A | phosphodiesterase 10A | 0.0393232 |
| CMIP | c-Maf inducing protein | 0.0385777 |
| CENPF | centromere protein F, 350/400kDa | 0.0384029 |
| FLNA | filamin A, alpha | 0.0382087 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0377336 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0371288 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0369136 |
| OGA | O-GlcNAcase | 0.0368519 |
| ARRDC3 | arrestin domain containing 3 | 0.036372 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0361437 |
| FMNL2 | formin-like 2 | 0.0357524 |
| ATP13A3 | ATPase type 13A3 | 0.0348358 |
| TPX2 | TPX2, microtubule-associated | 0.0342915 |
| MKI67 | marker of proliferation Ki-67 | 0.0342841 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0339906 |
| ENO1 | enolase 1, (alpha) | 0.0336495 |
| RNF220 | ring finger protein 220 | 0.0336296 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0331082 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0326615 |
| APP | amyloid beta (A4) precursor protein | 0.0323418 |
| HYOU1 | hypoxia up-regulated 1 | 0.0320075 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0316279 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0310278 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0309749 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0307654 |
| CDK19 | cyclin-dependent kinase 19 | 0.0306042 |
| YAP1 | Yes-associated protein 1 | 0.0305221 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0304324 |
| VIM | vimentin | 0.0300307 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.029894 |
| ANO6 | anoctamin 6 | 0.0296979 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296616 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0296542 |
| CTBP2 | C-terminal binding protein 2 | 0.0295784 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0290129 |
| FNIP1 | folliculin interacting protein 1 | 0.0287474 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0285327 |
| SETD5 | SET domain containing 5 | 0.0283459 |
| MYO10 | myosin X | 0.0283329 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0280756 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0279732 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0279703 |
| CALR | calreticulin | 0.0278423 |
| CD109 | CD109 molecule | 0.0277461 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0276788 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0276386 |
| UBC | ubiquitin C | 0.0275349 |
| FLNB | filamin B, beta | 0.0273976 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0270464 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0269433 |
| ITGAV | integrin, alpha V | 0.0266758 |
| NUP58 | nucleoporin 58 | 0.0265105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.212289 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1541 |
| ACTG1 | actin gamma 1 | -0.0808793 |
| TMSB10 | thymosin beta 10 | -0.0760066 |
| RPL35A | ribosomal protein L35a | -0.0698865 |
| RPLP1 | ribosomal protein, large, P1 | -0.0589146 |
| RPLP2 | ribosomal protein, large, P2 | -0.0496419 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0495238 |
| FTL | ferritin, light polypeptide | -0.0480886 |
| MT2A | metallothionein 2A | -0.0462408 |
| RPS24 | ribosomal protein S24 | -0.0433847 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0432178 |
| RPLP0 | ribosomal protein, large, P0 | -0.0374355 |
| CTSD | cathepsin D | -0.0368815 |
| S100A6 | S100 calcium binding protein A6 | -0.0341058 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0329694 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0326862 |
| RPL38 | ribosomal protein L38 | -0.0323554 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0321429 |
| AHNAK | AHNAK nucleoprotein | -0.0306192 |
| RPL34 | ribosomal protein L34 | -0.0295263 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0292059 |
| RPS6 | ribosomal protein S6 | -0.0279485 |
| RPS21 | ribosomal protein S21 | -0.0272965 |
| RPL28 | ribosomal protein L28 | -0.0271533 |
| GNAS | GNAS complex locus | -0.0266668 |
| RPS19 | ribosomal protein S19 | -0.0258788 |
| PTMA | prothymosin, alpha | -0.025513 |
| NPR2 | natriuretic peptide receptor 2 | -0.0239382 |
| RPS13 | ribosomal protein S13 | -0.0237519 |
| SQSTM1 | sequestosome 1 | -0.0233696 |
| RPL37A | ribosomal protein L37a | -0.0232074 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0228729 |
| THOC2 | THO complex 2 | -0.0220284 |
| RPL8 | ribosomal protein L8 | -0.0219821 |
| RPL27A | ribosomal protein L27a | -0.0218603 |
| IER3 | immediate early response 3 | -0.0210484 |
| RPS27A | ribosomal protein S27a | -0.0209499 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0207419 |
| HMGB1 | high mobility group box 1 | -0.0203439 |
| RPS3 | ribosomal protein S3 | -0.0203016 |
| WDR45B | WD repeat domain 45B | -0.0199109 |
| HLA-B | major histocompatibility complex, class I, B | -0.0198934 |
| RPL26 | ribosomal protein L26 | -0.0193142 |
| RPS28 | ribosomal protein S28 | -0.0193021 |
| MED29 | mediator complex subunit 29 | -0.0192228 |
| ZNF546 | zinc finger protein 546 | -0.0191657 |
| FUS | FUS RNA binding protein | -0.0190885 |
| OSMR | oncostatin M receptor | -0.019014 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0188034 |
| KPNB1 | karyopherin (importin) beta 1 | -0.018559 |
| EGR1 | early growth response 1 | -0.0184168 |
| RPS8 | ribosomal protein S8 | -0.0180329 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0176559 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0176258 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0167596 |
| NF1 | neurofibromin 1 | -0.0166249 |
| TBCA | tubulin folding cofactor A | -0.0164933 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0162073 |
| RPL31 | ribosomal protein L31 | -0.0159101 |
| FBXO27 | F-box protein 27 | -0.0158905 |
| RPS5 | ribosomal protein S5 | -0.0154761 |
| RPL9 | ribosomal protein L9 | -0.0152979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.015199 |
| RPS15 | ribosomal protein S15 | -0.0151763 |
| S100A9 | S100 calcium binding protein A9 | -0.0151368 |
| RACK1 | receptor for activated C kinase 1 | -0.0150731 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0149215 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) | -0.0148901 |
| RPL12 | ribosomal protein L12 | -0.0147125 |
| CAVIN1 | caveolae associated protein 1 | -0.014536 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.014509 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0144628 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0143252 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0141869 |
| SERF2 | small EDRK-rich factor 2 | -0.0141562 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0141222 |
| RPL6 | ribosomal protein L6 | -0.0139511 |
| PFN1 | profilin 1 | -0.0138587 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0138329 |
| RPS29 | ribosomal protein S29 | -0.0137926 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0135756 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0134711 |
| RPL36A | ribosomal protein L36a | -0.0134192 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0132814 |
| RPL32 | ribosomal protein L32 | -0.0130974 |
| RPL36 | ribosomal protein L36 | -0.013053 |
| ZNF780B | zinc finger protein 780B | -0.0130388 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0130287 |
| TRIM56 | tripartite motif containing 56 | -0.0128893 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0127931 |
| RPL23 | ribosomal protein L23 | -0.0127279 |
| BPTF | bromodomain PHD finger transcription factor | -0.0126622 |
| TP53 | tumor protein p53 | -0.0124746 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0122244 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0122196 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0120991 |
| RPL30 | ribosomal protein L30 | -0.0119423 |
| LMNA | lamin A/C | -0.011885 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0118695 |
