| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.14854 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0997891 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0961361 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0896389 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0874463 |
| RPL7 | ribosomal protein L7 | 0.0824353 |
| LAMB3 | laminin, beta 3 | 0.0799611 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0790813 |
| PTK2 | protein tyrosine kinase 2 | 0.0772184 |
| STC1 | stanniocalcin 1 | 0.075618 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0748312 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0732858 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0732206 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0722233 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0713948 |
| CORO1C | coronin, actin binding protein, 1C | 0.0710294 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0696537 |
| MCL1 | myeloid cell leukemia 1 | 0.0683332 |
| PGK1 | phosphoglycerate kinase 1 | 0.0677229 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0675723 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0669702 |
| OGA | O-GlcNAcase | 0.0661258 |
| FMNL2 | formin-like 2 | 0.0652029 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0646504 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0635449 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0624578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0619188 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0613948 |
| USP3 | ubiquitin specific peptidase 3 | 0.0567945 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0563362 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0558035 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0556079 |
| NUP58 | nucleoporin 58 | 0.055229 |
| ATP13A3 | ATPase type 13A3 | 0.0535559 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0532005 |
| TPD52 | tumor protein D52 | 0.0528824 |
| RBM39 | RNA binding motif protein 39 | 0.0527366 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0518053 |
| ZNF292 | zinc finger protein 292 | 0.0516783 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0516757 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0509277 |
| GOLGA4 | golgin A4 | 0.0494429 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0494017 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0491512 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0490043 |
| NCKAP1 | NCK-associated protein 1 | 0.048957 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0468396 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0466092 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0462919 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0462313 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0459622 |
| FLNA | filamin A, alpha | 0.0457989 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0457723 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0456469 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0453901 |
| BBX | bobby sox homolog (Drosophila) | 0.0446619 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0441871 |
| XPO1 | exportin 1 | 0.044127 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0440258 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0439161 |
| APP | amyloid beta (A4) precursor protein | 0.043476 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0434594 |
| SBF2 | SET binding factor 2 | 0.0431423 |
| ENO1 | enolase 1, (alpha) | 0.0424386 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0424066 |
| SRPK2 | SRSF protein kinase 2 | 0.0422755 |
| RLF | rearranged L-myc fusion | 0.0418662 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0415514 |
| PARD3 | par-3 family cell polarity regulator | 0.0414139 |
| RASA2 | RAS p21 protein activator 2 | 0.0412313 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0404713 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0403209 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0401209 |
| ABI1 | abl-interactor 1 | 0.0400861 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0399683 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0397637 |
| FLNB | filamin B, beta | 0.0396911 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0395129 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0394095 |
| WDR43 | WD repeat domain 43 | 0.0393876 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0393415 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0392287 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0391494 |
| NDRG1 | N-myc downstream regulated 1 | 0.0378372 |
| USP34 | ubiquitin specific peptidase 34 | 0.0377188 |
| CAPRIN2 | caprin family member 2 | 0.0373168 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0372812 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0370063 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0363969 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0363327 |
| CANX | calnexin | 0.0363024 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0362529 |
| RBM33 | RNA binding motif protein 33 | 0.0358524 |
| CLTC | clathrin, heavy chain (Hc) | 0.0351494 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.034991 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0347574 |
| PCBP2 | poly(rC) binding protein 2 | 0.0347367 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0344982 |
| ANO6 | anoctamin 6 | 0.0344118 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0341305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.12959 |
| ZNF438 | zinc finger protein 438 | -0.0847313 |
| FRMD6 | FERM domain containing 6 | -0.0638613 |
| NABP1 | nucleic acid binding protein 1 | -0.0567333 |
| HMGA2 | high mobility group AT-hook 2 | -0.0518247 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0428297 |
| POTEF | POTE ankyrin domain family, member F | -0.0411396 |
| MT2A | metallothionein 2A | -0.0410486 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0363877 |
| NAV3 | neuron navigator 3 | -0.0325014 |
| EGR1 | early growth response 1 | -0.0322872 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0276856 |
| INTS6 | integrator complex subunit 6 | -0.0273868 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0245196 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0235787 |
| FTL | ferritin, light polypeptide | -0.0232682 |
| GLRX | glutaredoxin (thioltransferase) | -0.0225558 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022046 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0215855 |
| RACK1 | receptor for activated C kinase 1 | -0.0212704 |
| RPS6 | ribosomal protein S6 | -0.0208049 |
| SP100 | SP100 nuclear antigen | -0.0193411 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0182455 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0180775 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.0177285 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0171203 |
| MSH4 | mutS homolog 4 | -0.0166725 |
| MYRFL | myelin regulatory factor-like | -0.0164882 |
| MTAP | methylthioadenosine phosphorylase | -0.0159548 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0158924 |
| PFN1 | profilin 1 | -0.0158886 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0158334 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0154818 |
| PLSCR1 | phospholipid scramblase 1 | -0.0153938 |
| CCDC91 | coiled-coil domain containing 91 | -0.0152177 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0151857 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0151595 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | -0.0150034 |
| ACTG1 | actin gamma 1 | -0.0150018 |
| RBM25 | RNA binding motif protein 25 | -0.0144863 |
| LRRC69 | leucine rich repeat containing 69 | -0.0140968 |
| KDSR | 3-ketodihydrosphingosine reductase | -0.0139729 |
| ANK2 | ankyrin 2, neuronal | -0.0138017 |
| CCDC138 | coiled-coil domain containing 138 | -0.013702 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0136685 |
| MX2 | MX dynamin-like GTPase 2 | -0.0135952 |
| SURF4 | surfeit 4 | -0.0135785 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0133848 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0130191 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0127856 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0125987 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0124593 |
| TBCA | tubulin folding cofactor A | -0.0124219 |
| S100A11 | S100 calcium binding protein A11 | -0.0122492 |
| TMEM165 | transmembrane protein 165 | -0.0121176 |
| SHISA5 | shisa family member 5 | -0.0120836 |
| PKP4 | plakophilin 4 | -0.0120663 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0120186 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0120172 |
| PHF14 | PHD finger protein 14 | -0.0120043 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0118496 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.011814 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0117247 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0116982 |
| AEBP2 | AE binding protein 2 | -0.0116901 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0116578 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0115757 |
| FKBP15 | FK506 binding protein 15, 133kDa | -0.011516 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0114884 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0114146 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0112981 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0112959 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0112518 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0111357 |
| ZNF91 | zinc finger protein 91 | -0.0111352 |
| SGMS2 | sphingomyelin synthase 2 | -0.0111326 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0110851 |
| CCDC18 | coiled-coil domain containing 18 | -0.011042 |
| SLC41A1 | solute carrier family 41 (magnesium transporter), member 1 | -0.0109774 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.010897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0107928 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.0106298 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0105373 |
| FOXP1 | forkhead box P1 | -0.0104577 |
| RGS5 | regulator of G-protein signaling 5 | -0.0104423 |
| TUBA1B | tubulin, alpha 1b | -0.0103927 |
| MIPOL1 | mirror-image polydactyly 1 | -0.010361 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.010338 |
| HNF4G | hepatocyte nuclear factor 4, gamma | -0.0102359 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.010231 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | -0.0101564 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0101273 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0100757 |
| TCF12 | transcription factor 12 | -0.0100722 |
| RPLP1 | ribosomal protein, large, P1 | -0.0100608 |
| IL7 | interleukin 7 | -0.0100601 |
| R3HDM1 | R3H domain containing 1 | -0.0100499 |
| CFAP54 | cilia and flagella associated 54 | -0.0100449 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.010042 |
| S100A9 | S100 calcium binding protein A9 | -0.00986085 |
