| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.192732 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.159702 |
| FNDC3B | fibronectin type III domain containing 3B | 0.116698 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.107972 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0958638 |
| STC1 | stanniocalcin 1 | 0.0942638 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0851723 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0825227 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0661877 |
| ANLN | anillin, actin binding protein | 0.0610938 |
| ZNF292 | zinc finger protein 292 | 0.0609759 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.058973 |
| MSN | moesin | 0.058641 |
| SMAD3 | SMAD family member 3 | 0.0577726 |
| XPO1 | exportin 1 | 0.0566879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0551717 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0542321 |
| NAV2 | neuron navigator 2 | 0.0518116 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0505051 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0502992 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0499635 |
| TGM2 | transglutaminase 2 | 0.04851 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0480089 |
| PGK1 | phosphoglycerate kinase 1 | 0.0477487 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.046974 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0467802 |
| ACTN4 | actinin, alpha 4 | 0.0458815 |
| PLEC | plectin | 0.0452501 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0449296 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0437914 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0431196 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0404737 |
| CORO1C | coronin, actin binding protein, 1C | 0.0397651 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0397486 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0396457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0396444 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.039477 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0394565 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0393908 |
| CENPF | centromere protein F, 350/400kDa | 0.0393522 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0383729 |
| TPX2 | TPX2, microtubule-associated | 0.0381386 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0380351 |
| NCKAP1 | NCK-associated protein 1 | 0.0380017 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0375438 |
| DSCAM | Down syndrome cell adhesion molecule | 0.037443 |
| FLNB | filamin B, beta | 0.0373616 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0368044 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0366369 |
| FLNA | filamin A, alpha | 0.0364768 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0359028 |
| SPAG9 | sperm associated antigen 9 | 0.0348371 |
| OGA | O-GlcNAcase | 0.0346476 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0345083 |
| PCBP2 | poly(rC) binding protein 2 | 0.0343713 |
| MKI67 | marker of proliferation Ki-67 | 0.0342721 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0336251 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0334991 |
| YEATS2 | YEATS domain containing 2 | 0.0330591 |
| LOXL2 | lysyl oxidase-like 2 | 0.0329128 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0329103 |
| WAC | WW domain containing adaptor with coiled-coil | 0.032569 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0325264 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0323892 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0319977 |
| FAM13A | family with sequence similarity 13, member A | 0.031913 |
| FOXJ3 | forkhead box J3 | 0.0318769 |
| TFG | TRK-fused gene | 0.0316552 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0315382 |
| HELZ | helicase with zinc finger | 0.031348 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0310646 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0309759 |
| ATP13A3 | ATPase type 13A3 | 0.0307602 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0306801 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.030494 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0304598 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0302826 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0299675 |
| CTNNBL1 | catenin, beta like 1 | 0.0299455 |
| CD109 | CD109 molecule | 0.0298032 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0297245 |
| RLIM | ring finger protein, LIM domain interacting | 0.0296568 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0295879 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0292767 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0287834 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0287793 |
| CD44 | CD44 molecule (Indian blood group) | 0.0287523 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0286716 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0284738 |
| DIAPH3 | diaphanous-related formin 3 | 0.0284177 |
| RBM39 | RNA binding motif protein 39 | 0.0283376 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0281754 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0281355 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.028057 |
| AFAP1 | actin filament associated protein 1 | 0.0277239 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0277197 |
| ARRDC3 | arrestin domain containing 3 | 0.0275899 |
| SMOX | spermine oxidase | 0.0274101 |
| HMGB2 | high mobility group box 2 | 0.0270551 |
| AFDN | afadin, adherens junction formation factor | 0.0268122 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.155635 |
| MT2A | metallothionein 2A | -0.128081 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.110419 |
| FTL | ferritin, light polypeptide | -0.107795 |
| TMSB10 | thymosin beta 10 | -0.0924001 |
| COL1A2 | collagen, type I, alpha 2 | -0.0903309 |
| COL1A1 | collagen, type I, alpha 1 | -0.0807454 |
| HLA-B | major histocompatibility complex, class I, B | -0.0737829 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0728468 |
| B2M | beta-2-microglobulin | -0.0674697 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0589263 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0516558 |
| PTMA | prothymosin, alpha | -0.0453863 |
| RRBP1 | ribosome binding protein 1 | -0.0450599 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0427632 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0422442 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0421277 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0410625 |
| CDH13 | cadherin 13 | -0.0405404 |
| ASPH | aspartate beta-hydroxylase | -0.040317 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.039938 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0397706 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0386538 |
| TPM4 | tropomyosin 4 | -0.0374085 |
| EGR1 | early growth response 1 | -0.0372507 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0370326 |
| RPL35A | ribosomal protein L35a | -0.0363883 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347388 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0344128 |
| FRMD4A | FERM domain containing 4A | -0.0342682 |
| TMEM178B | transmembrane protein 178B | -0.0341016 |
| RPLP1 | ribosomal protein, large, P1 | -0.0332189 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.031931 |
| S100A6 | S100 calcium binding protein A6 | -0.0315744 |
| RPS19 | ribosomal protein S19 | -0.0311213 |
| ACTG1 | actin gamma 1 | -0.0311023 |
| CALR | calreticulin | -0.030695 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0305588 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0304405 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0297984 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.029223 |
| RPL37A | ribosomal protein L37a | -0.0285308 |
| GNAS | GNAS complex locus | -0.0284743 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0283109 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0276723 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0276212 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275082 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0274687 |
| LOX | lysyl oxidase | -0.0273447 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.026614 |
| S100A9 | S100 calcium binding protein A9 | -0.0265992 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0264792 |
| MAGED1 | melanoma antigen family D1 | -0.0260564 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0254479 |
| SERF2 | small EDRK-rich factor 2 | -0.0252262 |
| S100A10 | S100 calcium binding protein A10 | -0.0248995 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0248565 |
| RPS6 | ribosomal protein S6 | -0.0247133 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0240622 |
| NRP1 | neuropilin 1 | -0.0239427 |
| SP100 | SP100 nuclear antigen | -0.0238898 |
| NAV1 | neuron navigator 1 | -0.0238434 |
| TNNC1 | troponin C type 1 (slow) | -0.0237704 |
| NBEA | neurobeachin | -0.0235974 |
| TPM1 | tropomyosin 1 (alpha) | -0.0234915 |
| PFN1 | profilin 1 | -0.0234416 |
| PKM | pyruvate kinase, muscle | -0.0232567 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0232239 |
| RPS13 | ribosomal protein S13 | -0.0230928 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.022873 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0227359 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0227317 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0223571 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0221813 |
| CAVIN1 | caveolae associated protein 1 | -0.0216218 |
| RPL23 | ribosomal protein L23 | -0.0213458 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0211971 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0211172 |
| RPS21 | ribosomal protein S21 | -0.0209272 |
| LMNA | lamin A/C | -0.0209217 |
| RPL36 | ribosomal protein L36 | -0.0207274 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0205324 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0203622 |
| OXR1 | oxidation resistance 1 | -0.020227 |
| HM13 | histocompatibility (minor) 13 | -0.0202231 |
| RPS3 | ribosomal protein S3 | -0.0200774 |
| RPS8 | ribosomal protein S8 | -0.0198029 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0197542 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.019754 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0196565 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0195814 |
| IER3 | immediate early response 3 | -0.0194334 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0192802 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0192134 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0191227 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0188359 |
| RPS12 | ribosomal protein S12 | -0.0184627 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.01833 |
| INTS6 | integrator complex subunit 6 | -0.0182797 |
| RPL34 | ribosomal protein L34 | -0.0182147 |
