| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.163069 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.143328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.108221 |
| LSAMP | limbic system-associated membrane protein | 0.105337 |
| NRG3 | neuregulin 3 | 0.102037 |
| MSI2 | musashi RNA-binding protein 2 | 0.0933888 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0863533 |
| MSN | moesin | 0.0842061 |
| FLNA | filamin A, alpha | 0.0787817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.072316 |
| SPAG9 | sperm associated antigen 9 | 0.071181 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0689693 |
| NLGN1 | neuroligin 1 | 0.065943 |
| SEPTIN9 | septin 9 | 0.063483 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.062598 |
| PLEC | plectin | 0.0615122 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0574788 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0570764 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0555839 |
| SETD5 | SET domain containing 5 | 0.0552168 |
| RAD51B | RAD51 paralog B | 0.0546202 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0529821 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0525879 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0518493 |
| DST | dystonin | 0.0503935 |
| FMNL2 | formin-like 2 | 0.0500451 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0497528 |
| FLNB | filamin B, beta | 0.049323 |
| NOTCH2 | notch 2 | 0.0485976 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0470321 |
| BBX | bobby sox homolog (Drosophila) | 0.0466935 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0460016 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.045342 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0447552 |
| ENO1 | enolase 1, (alpha) | 0.0446293 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.044577 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0442402 |
| PTK2 | protein tyrosine kinase 2 | 0.0439429 |
| TPM3 | tropomyosin 3 | 0.0432159 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0424475 |
| PRELID2 | PRELI domain containing 2 | 0.0422669 |
| NAV2 | neuron navigator 2 | 0.0411457 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0409057 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0408865 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.040654 |
| SBF2 | SET binding factor 2 | 0.0403289 |
| CABIN1 | calcineurin binding protein 1 | 0.0397418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0393905 |
| XPO1 | exportin 1 | 0.0390663 |
| CTTN | cortactin | 0.038971 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0383684 |
| OGA | O-GlcNAcase | 0.0383236 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0382609 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0380556 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0377384 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0376779 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0368902 |
| TFG | TRK-fused gene | 0.036866 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0365774 |
| MEF2A | myocyte enhancer factor 2A | 0.0363116 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0359454 |
| CFAP20DC | CFAP20 domain containing | 0.0357699 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0357067 |
| PCBP2 | poly(rC) binding protein 2 | 0.0355103 |
| HELZ | helicase with zinc finger | 0.0353283 |
| RPL3 | ribosomal protein L3 | 0.0352058 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0349541 |
| FRMD4A | FERM domain containing 4A | 0.034882 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0348274 |
| LDHA | lactate dehydrogenase A | 0.0348117 |
| YEATS2 | YEATS domain containing 2 | 0.0346729 |
| ZNF292 | zinc finger protein 292 | 0.0346235 |
| DIAPH1 | diaphanous-related formin 1 | 0.0346216 |
| CTBP2 | C-terminal binding protein 2 | 0.0345972 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0345498 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0344936 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341557 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.033598 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0332705 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0332516 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0330757 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0325515 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0322905 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0322535 |
| TNNC1 | troponin C type 1 (slow) | 0.0321266 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0319561 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0319509 |
| ANGPTL4 | angiopoietin-like 4 | 0.0317798 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0317214 |
| CD109 | CD109 molecule | 0.0314503 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0309615 |
| ACTN4 | actinin, alpha 4 | 0.0302074 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0300005 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0299922 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0299223 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0297992 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295467 |
| ATXN1 | ataxin 1 | 0.0294114 |
| USP3 | ubiquitin specific peptidase 3 | 0.028974 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0289252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.093354 |
| FMN1 | formin 1 | -0.0846583 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834638 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0834132 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0596892 |
| RPS3 | ribosomal protein S3 | -0.0547321 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0529247 |
| RPLP1 | ribosomal protein, large, P1 | -0.0472501 |
| FTL | ferritin, light polypeptide | -0.0463699 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.04421 |
| RPS6 | ribosomal protein S6 | -0.0395411 |
| ACTG1 | actin gamma 1 | -0.0395195 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0334009 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0314619 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0313637 |
| MT1X | metallothionein 1X | -0.0309641 |
| RPL35A | ribosomal protein L35a | -0.0290336 |
| FRMD5 | FERM domain containing 5 | -0.0278571 |
| RASAL2 | RAS protein activator like 2 | -0.0274243 |
| TMSB10 | thymosin beta 10 | -0.026872 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0262095 |
| PCNX4 | pecanex 4 | -0.0261484 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02542 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0243036 |
| TP63 | tumor protein p63 | -0.0236259 |
| RPL38 | ribosomal protein L38 | -0.023505 |
| RPS8 | ribosomal protein S8 | -0.0218791 |
| RPLP2 | ribosomal protein, large, P2 | -0.0213122 |
| RPL32 | ribosomal protein L32 | -0.0213051 |
| RPL34 | ribosomal protein L34 | -0.0207989 |
| RACK1 | receptor for activated C kinase 1 | -0.0204277 |
| RPS13 | ribosomal protein S13 | -0.0199298 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0192072 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0184603 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.018279 |
| APOD | apolipoprotein D | -0.0180472 |
| RPL12 | ribosomal protein L12 | -0.017909 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0177877 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0177248 |
| RPL31 | ribosomal protein L31 | -0.0170627 |
| RPL5 | ribosomal protein L5 | -0.0168471 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0168255 |
| HLA-B | major histocompatibility complex, class I, B | -0.016623 |
| RPS21 | ribosomal protein S21 | -0.0165768 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0164765 |
| RPL37A | ribosomal protein L37a | -0.0162455 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0160568 |
| ERBIN | erbb2 interacting protein | -0.0158463 |
| IER3 | immediate early response 3 | -0.0158435 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0157328 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.0156024 |
| RPS29 | ribosomal protein S29 | -0.0154702 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0154537 |
| CCND1 | cyclin D1 | -0.0153915 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0153602 |
| RPL36A | ribosomal protein L36a | -0.0152675 |
| TXNRD1 | thioredoxin reductase 1 | -0.0152069 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0151701 |
| RPS24 | ribosomal protein S24 | -0.0150944 |
| DUSP6 | dual specificity phosphatase 6 | -0.0150775 |
| RPL36 | ribosomal protein L36 | -0.0149201 |
| ASTN2 | astrotactin 2 | -0.0148336 |
| RPL9 | ribosomal protein L9 | -0.0146896 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0145793 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0144271 |
| EGR1 | early growth response 1 | -0.0143039 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0142862 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0141442 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.014129 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0140665 |
| NRXN3 | neurexin 3 | -0.0140349 |
| RPL28 | ribosomal protein L28 | -0.0140264 |
| CDK6 | cyclin-dependent kinase 6 | -0.0139489 |
| TBCA | tubulin folding cofactor A | -0.0139037 |
| RPS19 | ribosomal protein S19 | -0.0138413 |
| KLF6 | Kruppel-like factor 6 | -0.0136877 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0136692 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0132623 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0130998 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0128331 |
| CD63 | CD63 molecule | -0.0128158 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0127947 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0127137 |
| S100A9 | S100 calcium binding protein A9 | -0.0126601 |
| FAM222B | family with sequence similarity 222, member B | -0.01251 |
| FBXO32 | F-box protein 32 | -0.0124812 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0124492 |
| ULK4 | unc-51 like kinase 4 | -0.0124004 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.012234 |
| CD96 | CD96 molecule | -0.0121832 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0120457 |
| ANKRD28 | ankyrin repeat domain 28 | -0.01202 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0120046 |
| SNX24 | sorting nexin 24 | -0.0119507 |
| TNPO1 | transportin 1 | -0.0118236 |
| ATXN2 | ataxin 2 | -0.0116947 |
| FSTL5 | follistatin-like 5 | -0.0116921 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0116863 |
| PTTG1 | pituitary tumor-transforming 1 | -0.0116259 |
| SKP1 | S-phase kinase-associated protein 1 | -0.011621 |
