| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.28976 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.152583 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.144812 |
| FN1 | fibronectin 1 | 0.134659 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.125111 |
| LOXL2 | lysyl oxidase-like 2 | 0.060636 |
| SMAD3 | SMAD family member 3 | 0.0598873 |
| FLNA | filamin A, alpha | 0.0598558 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.057274 |
| CD44 | CD44 molecule (Indian blood group) | 0.0571406 |
| VIM | vimentin | 0.0540767 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0527488 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.05219 |
| COL5A1 | collagen, type V, alpha 1 | 0.0516281 |
| FAM20C | family with sequence similarity 20, member C | 0.0512648 |
| CALD1 | caldesmon 1 | 0.0510036 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0509528 |
| ATP13A3 | ATPase type 13A3 | 0.0503617 |
| ACTN4 | actinin, alpha 4 | 0.0490162 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0479284 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0458486 |
| VCL | vinculin | 0.0456407 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0455366 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0417313 |
| RIN2 | Ras and Rab interactor 2 | 0.0417218 |
| CDK6 | cyclin-dependent kinase 6 | 0.041585 |
| PGK1 | phosphoglycerate kinase 1 | 0.041383 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0406605 |
| MAP4 | microtubule-associated protein 4 | 0.0405528 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0404864 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0404844 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0404054 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0403383 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0402663 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0401671 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0401549 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.039696 |
| TPM4 | tropomyosin 4 | 0.0395618 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0393633 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0388688 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0384282 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.038134 |
| NF1 | neurofibromin 1 | 0.0378086 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0373614 |
| ARRDC3 | arrestin domain containing 3 | 0.0371885 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0371032 |
| PLEC | plectin | 0.0368106 |
| PRELID2 | PRELI domain containing 2 | 0.0365136 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0364737 |
| PRKCA | protein kinase C, alpha | 0.0357268 |
| NRXN3 | neurexin 3 | 0.0353909 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0353624 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0347241 |
| MAP1B | microtubule-associated protein 1B | 0.0341267 |
| CCDC14 | coiled-coil domain containing 14 | 0.0340809 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0340376 |
| AOPEP | aminopeptidase O (putative) | 0.0335398 |
| ECE1 | endothelin converting enzyme 1 | 0.0335016 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.032088 |
| PTK2 | protein tyrosine kinase 2 | 0.0317345 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0308621 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0306118 |
| ANXA5 | annexin A5 | 0.0303061 |
| TNS3 | tensin 3 | 0.0297563 |
| GLIS3 | GLIS family zinc finger 3 | 0.0293468 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0293222 |
| RNF213 | ring finger protein 213 | 0.0291311 |
| ITGB5 | integrin, beta 5 | 0.0291002 |
| RPL37A | ribosomal protein L37a | 0.0289346 |
| RNF145 | ring finger protein 145 | 0.0287272 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0286614 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0285686 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0284368 |
| FOXK1 | forkhead box K1 | 0.0284009 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0283902 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.028314 |
| COL5A2 | collagen, type V, alpha 2 | 0.0281648 |
| TLN1 | talin 1 | 0.0280962 |
| FER | fer (fps/fes related) tyrosine kinase | 0.027662 |
| CDC73 | cell division cycle 73 | 0.0276521 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0275653 |
| ENO1 | enolase 1, (alpha) | 0.027558 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0274983 |
| KIF5B | kinesin family member 5B | 0.0273185 |
| CTNNBL1 | catenin, beta like 1 | 0.0269468 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.026866 |
| SNX9 | sorting nexin 9 | 0.0267095 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0265941 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0264478 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0262775 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0261678 |
| FAM219A | family with sequence similarity 219, member A | 0.026061 |
| RPL26 | ribosomal protein L26 | 0.0259578 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0259084 |
| FLOT1 | flotillin 1 | 0.0256111 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0254207 |
| AFDN | afadin, adherens junction formation factor | 0.0254186 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0253984 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0253735 |
| CEP350 | centrosomal protein 350kDa | 0.0250633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.175075 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157045 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133819 |
| TMSB10 | thymosin beta 10 | -0.118331 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.102092 |
| MT2A | metallothionein 2A | -0.100407 |
| HLA-B | major histocompatibility complex, class I, B | -0.082784 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0711573 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0692633 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0627266 |
| STC1 | stanniocalcin 1 | -0.0605934 |
| COL1A2 | collagen, type I, alpha 2 | -0.0586374 |
| CCNI | cyclin I | -0.0512637 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0510114 |
| LOX | lysyl oxidase | -0.0504093 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0468859 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0464776 |
| PTMA | prothymosin, alpha | -0.0456766 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0456451 |
| COL1A1 | collagen, type I, alpha 1 | -0.0446147 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0442982 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0441267 |
| FNIP1 | folliculin interacting protein 1 | -0.0422295 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.041436 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0404657 |
| IL6 | interleukin 6 | -0.0401722 |
| COG5 | component of oligomeric golgi complex 5 | -0.0399425 |
| FUS | FUS RNA binding protein | -0.0390076 |
| FTL | ferritin, light polypeptide | -0.0373588 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0372421 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.036757 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0363352 |
| JAK1 | Janus kinase 1 | -0.0362758 |
| TPX2 | TPX2, microtubule-associated | -0.0357097 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0351426 |
| MYOF | myoferlin | -0.0349085 |
| RASAL2 | RAS protein activator like 2 | -0.0344964 |
| SPAG9 | sperm associated antigen 9 | -0.0341211 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.03374 |
| ASPH | aspartate beta-hydroxylase | -0.0337249 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0333371 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | -0.0330453 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0327965 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0313622 |
| CANX | calnexin | -0.0312972 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.031238 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0312159 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0310728 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0307791 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0302054 |
| GOLGA4 | golgin A4 | -0.0295264 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0288265 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0284379 |
| TPI1 | triosephosphate isomerase 1 | -0.0282515 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0280465 |
| NUCB2 | nucleobindin 2 | -0.0279223 |
| SRP72 | signal recognition particle 72kDa | -0.0278224 |
| MEF2A | myocyte enhancer factor 2A | -0.0276923 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0273879 |
| CAVIN1 | caveolae associated protein 1 | -0.0273127 |
| HM13 | histocompatibility (minor) 13 | -0.026926 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | -0.0268953 |
| SDC4 | syndecan 4 | -0.0268152 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0266246 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0265189 |
| SRP54 | signal recognition particle 54kDa | -0.026448 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0263435 |
| BRD4 | bromodomain containing 4 | -0.0258707 |
| S100A10 | S100 calcium binding protein A10 | -0.0257524 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0256265 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.025501 |
| RLF | rearranged L-myc fusion | -0.0254528 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0249562 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0246514 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0241893 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0240683 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0240462 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0237116 |
| WAC | WW domain containing adaptor with coiled-coil | -0.023494 |
| ANXA2 | annexin A2 | -0.0234751 |
| ANLN | anillin, actin binding protein | -0.0234315 |
| SEPTIN7 | septin 7 | -0.023217 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0232157 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0231112 |
| GLG1 | golgi glycoprotein 1 | -0.023012 |
| PAPOLA | poly(A) polymerase alpha | -0.0227956 |
| GNAS | GNAS complex locus | -0.0227945 |
| COPA | coatomer protein complex, subunit alpha | -0.0227782 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.022604 |
| SEC61G | Sec61 gamma subunit | -0.0224993 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0224657 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0223136 |
| FMNL2 | formin-like 2 | -0.022287 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0217963 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0217892 |
| HELZ | helicase with zinc finger | -0.0217822 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.021587 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0214597 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0214024 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0212859 |
