| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rutin (trihydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0876833 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0817585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0770199 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0764179 |
| CEP250 | centrosomal protein 250kDa | 0.0750397 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0736524 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0728956 |
| GOLGA4 | golgin A4 | 0.0694525 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.066888 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.066803 |
| MSN | moesin | 0.0646956 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0630618 |
| GOLGB1 | golgin B1 | 0.0611123 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0607796 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0604705 |
| ZNF292 | zinc finger protein 292 | 0.0591958 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0582525 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0563885 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0559952 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0551976 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0546231 |
| SPAG9 | sperm associated antigen 9 | 0.0529381 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0514398 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0497107 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0480809 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0478439 |
| FMNL2 | formin-like 2 | 0.0456502 |
| TPM3 | tropomyosin 3 | 0.0452188 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0451005 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0416884 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0416844 |
| FLNA | filamin A, alpha | 0.0412633 |
| WDR43 | WD repeat domain 43 | 0.0401803 |
| CCNL1 | cyclin L1 | 0.0394566 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0393653 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0387789 |
| TXNRD1 | thioredoxin reductase 1 | 0.0387723 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0385677 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0384542 |
| PCBP2 | poly(rC) binding protein 2 | 0.0382809 |
| YAP1 | Yes-associated protein 1 | 0.0378596 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0378212 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0372407 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.037046 |
| ATP13A3 | ATPase type 13A3 | 0.0365364 |
| NBAS | neuroblastoma amplified sequence | 0.0363749 |
| RBM33 | RNA binding motif protein 33 | 0.0361007 |
| CALR | calreticulin | 0.0350944 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0343144 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0341528 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0340516 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0339753 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0337868 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0337635 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0333584 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0331881 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0330863 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0328608 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0325938 |
| SET | SET nuclear proto-oncogene | 0.0324624 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0323095 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0322162 |
| YME1L1 | YME1-like 1 ATPase | 0.0320407 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0319215 |
| ARRDC3 | arrestin domain containing 3 | 0.0318168 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0313545 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0309564 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0308966 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0308339 |
| NUP58 | nucleoporin 58 | 0.0306155 |
| NOP58 | NOP58 ribonucleoprotein | 0.0298276 |
| CALU | calumenin | 0.02964 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0295033 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0294878 |
| PER1 | period circadian clock 1 | 0.0294622 |
| XPO1 | exportin 1 | 0.029421 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0293485 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0293022 |
| TMEM39A | transmembrane protein 39A | 0.0291233 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0288354 |
| VIM | vimentin | 0.0287862 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.028732 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0286102 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0283897 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0283636 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0283181 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0281546 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0281119 |
| NCKAP1 | NCK-associated protein 1 | 0.0280766 |
| TXNIP | thioredoxin interacting protein | 0.0280603 |
| RBM5 | RNA binding motif protein 5 | 0.0278719 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0278438 |
| RPL19 | ribosomal protein L19 | 0.0271656 |
| RNF145 | ring finger protein 145 | 0.0271592 |
| MCL1 | myeloid cell leukemia 1 | 0.0271095 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0270645 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0269272 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0268557 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0268511 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0268066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.243831 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0931453 |
| TMSB10 | thymosin beta 10 | -0.0897621 |
| HMGA2 | high mobility group AT-hook 2 | -0.0631107 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0622934 |
| IER3 | immediate early response 3 | -0.0606153 |
| POTEF | POTE ankyrin domain family, member F | -0.0593413 |
| AHNAK | AHNAK nucleoprotein | -0.0490426 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0483076 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0466981 |
| RPLP1 | ribosomal protein, large, P1 | -0.0461267 |
| ANXA2 | annexin A2 | -0.045877 |
| DEK | DEK proto-oncogene | -0.0446792 |
| MT2A | metallothionein 2A | -0.0434828 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0414692 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0405183 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0390321 |
| IGF2 | insulin-like growth factor 2 | -0.0388431 |
| FMN1 | formin 1 | -0.0384652 |
| VCL | vinculin | -0.037562 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0375469 |
| PURA | purine-rich element binding protein A | -0.0356964 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0356551 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0356374 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0348553 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0345559 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0340096 |
| PRR16 | proline rich 16 | -0.0335469 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0333124 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0331762 |
| ANGPTL4 | angiopoietin-like 4 | -0.0331366 |
| RPL35A | ribosomal protein L35a | -0.0331356 |
| PRKCA | protein kinase C, alpha | -0.0327 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0326383 |
| SVIL | supervillin | -0.0325961 |
| GPC6 | glypican 6 | -0.0324484 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0321881 |
| ANO6 | anoctamin 6 | -0.032167 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0317743 |
| H3-3B | H3.3 histone B | -0.0315355 |
| ZNF609 | zinc finger protein 609 | -0.0313814 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.030691 |
| S100A10 | S100 calcium binding protein A10 | -0.0305886 |
| RPS19 | ribosomal protein S19 | -0.0303521 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0299456 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0297816 |
| COL5A1 | collagen, type V, alpha 1 | -0.0294445 |
| YBX3 | Y box binding protein 3 | -0.0288112 |
| PCED1B | PC-esterase domain containing 1B | -0.0284879 |
| BBX | bobby sox homolog (Drosophila) | -0.0284222 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.028212 |
| AOPEP | aminopeptidase O (putative) | -0.0280892 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0271054 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0269167 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0265152 |
| COMMD10 | COMM domain containing 10 | -0.026237 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.026162 |
| EFNA5 | ephrin-A5 | -0.0261543 |
| ACTG1 | actin gamma 1 | -0.0261216 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.025923 |
| MKI67 | marker of proliferation Ki-67 | -0.0258816 |
| HLA-B | major histocompatibility complex, class I, B | -0.0258762 |
| NF1 | neurofibromin 1 | -0.0257416 |
| RIGI | RNA sensor RIG-I | -0.0254929 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0254344 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0252949 |
| RSF1 | remodeling and spacing factor 1 | -0.0251892 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0249725 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0248311 |
| NRG1 | neuregulin 1 | -0.0247142 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0247097 |
| ZNF83 | zinc finger protein 83 | -0.0246244 |
| MT1X | metallothionein 1X | -0.0243724 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.024255 |
| SDC4 | syndecan 4 | -0.0239959 |
| CCND1 | cyclin D1 | -0.0232839 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0232712 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0232405 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0230233 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0230029 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.022948 |
| NLK | nemo-like kinase | -0.0229046 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0228669 |
| SBF2 | SET binding factor 2 | -0.0227658 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0226994 |
| CCNH | cyclin H | -0.0225915 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0225792 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0225411 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.022461 |
| ASTN2 | astrotactin 2 | -0.0224512 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0223702 |
| YY1 | YY1 transcription factor | -0.0223635 |
| JAK1 | Janus kinase 1 | -0.022262 |
| NBEA | neurobeachin | -0.0219133 |
| FUS | FUS RNA binding protein | -0.0218524 |
| BMERB1 | bMERB domain containing 1 | -0.0218067 |
| DGKE | diacylglycerol kinase, epsilon 64kDa | -0.021751 |
| TAOK1 | TAO kinase 1 | -0.0217025 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0216953 |
| RPL34 | ribosomal protein L34 | -0.0216727 |
