| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rutin (trihydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rutin (trihydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0975171 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0905002 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0788933 |
| ACTN4 | actinin, alpha 4 | 0.0771243 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0722156 |
| PLEC | plectin | 0.0604753 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0572488 |
| DSPP | dentin sialophosphoprotein | 0.0564604 |
| FLNA | filamin A, alpha | 0.0564023 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0558624 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0541473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0526804 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0488076 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0485521 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0484398 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0472264 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0417426 |
| MED13L | mediator complex subunit 13-like | 0.0411981 |
| MYO10 | myosin X | 0.0400096 |
| XPO1 | exportin 1 | 0.0371493 |
| ZNF292 | zinc finger protein 292 | 0.0366682 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0364684 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0362125 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0356779 |
| AFDN | afadin, adherens junction formation factor | 0.0351594 |
| NCKAP1 | NCK-associated protein 1 | 0.0346442 |
| RBM39 | RNA binding motif protein 39 | 0.0338575 |
| MYO5B | myosin VB | 0.0337412 |
| MTMR3 | myotubularin related protein 3 | 0.032093 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0304812 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.030436 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0294863 |
| RBM33 | RNA binding motif protein 33 | 0.029368 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0291332 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0289789 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.028843 |
| FAT1 | FAT atypical cadherin 1 | 0.0284443 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0275627 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0274049 |
| USP3 | ubiquitin specific peptidase 3 | 0.0273128 |
| YAP1 | Yes-associated protein 1 | 0.0268249 |
| PCBP2 | poly(rC) binding protein 2 | 0.0268213 |
| OGA | O-GlcNAcase | 0.0265093 |
| SNX9 | sorting nexin 9 | 0.02636 |
| CCNL1 | cyclin L1 | 0.026306 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0261277 |
| TFG | TRK-fused gene | 0.0259847 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0258292 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0252681 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0249272 |
| HOXA3 | homeobox A3 | 0.024776 |
| KRT18 | keratin 18, type I | 0.0244795 |
| RREB1 | ras responsive element binding protein 1 | 0.0242704 |
| KRT8 | keratin 8, type II | 0.024217 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240112 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0237537 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0237301 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0235984 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0235638 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0233771 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0233548 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0230335 |
| TPM3 | tropomyosin 3 | 0.0229887 |
| TUFT1 | tuftelin 1 | 0.0226768 |
| RANBP9 | RAN binding protein 9 | 0.0225111 |
| RPL19 | ribosomal protein L19 | 0.0223405 |
| RYBP | RING1 and YY1 binding protein | 0.0223368 |
| DIDO1 | death inducer-obliterator 1 | 0.0222525 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0222473 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0221564 |
| ANXA11 | annexin A11 | 0.0219986 |
| APP | amyloid beta (A4) precursor protein | 0.0218859 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0218835 |
| CPLX2 | complexin 2 | 0.0217493 |
| MATR3 | matrin 3 | 0.0217087 |
| ARRDC3 | arrestin domain containing 3 | 0.0214082 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0212446 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0211417 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0211364 |
| RYK | receptor-like tyrosine kinase | 0.0210152 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0208425 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0207713 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.020719 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0206354 |
| CALR | calreticulin | 0.0206299 |
| ATL2 | atlastin GTPase 2 | 0.0206285 |
| UBQLN1 | ubiquilin 1 | 0.0206067 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0202326 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0201243 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.020113 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0200991 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0197712 |
| TJP2 | tight junction protein 2 | 0.0197077 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0195492 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0195451 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0195263 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0195076 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0194258 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0194133 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0194052 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.161263 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.118046 |
| PTMA | prothymosin, alpha | -0.0910949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0794256 |
| EHBP1 | EH domain binding protein 1 | -0.0695281 |
| TMSB10 | thymosin beta 10 | -0.0653101 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.063435 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0619782 |
| EGR1 | early growth response 1 | -0.0574114 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0493606 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0466695 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0463611 |
| NEBL | nebulette | -0.0460782 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0457405 |
| RPS6 | ribosomal protein S6 | -0.0448302 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0447364 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0446456 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0438003 |
| RPL35A | ribosomal protein L35a | -0.0427642 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0419076 |
| RPS21 | ribosomal protein S21 | -0.0414812 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0399831 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0374435 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0364099 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0357828 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0354665 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0353607 |
| CUX1 | cut-like homeobox 1 | -0.0346809 |
| BCL2L1 | BCL2-like 1 | -0.0345765 |
| PKP4 | plakophilin 4 | -0.0341747 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.033878 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0336666 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0329866 |
| RPS13 | ribosomal protein S13 | -0.0327436 |
| EXOC4 | exocyst complex component 4 | -0.0325927 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0325209 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0324987 |
| GNAS | GNAS complex locus | -0.0322911 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0322057 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0319615 |
| IER3 | immediate early response 3 | -0.0318388 |
| FRMD5 | FERM domain containing 5 | -0.031649 |
| NFIA | nuclear factor I/A | -0.0312486 |
| CDK13 | cyclin-dependent kinase 13 | -0.0309501 |
| CADPS | Ca++-dependent secretion activator | -0.0306886 |
| RPL31 | ribosomal protein L31 | -0.030586 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0305 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0302294 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.030222 |
| EPCAM | epithelial cell adhesion molecule | -0.029857 |
| NF1 | neurofibromin 1 | -0.0293294 |
| PLSCR1 | phospholipid scramblase 1 | -0.0293165 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0289238 |
| MX2 | MX dynamin-like GTPase 2 | -0.0285897 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0285177 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0284984 |
| GOLGA4 | golgin A4 | -0.0281571 |
| S100A9 | S100 calcium binding protein A9 | -0.0280274 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279928 |
| RPL8 | ribosomal protein L8 | -0.0276905 |
| RPLP1 | ribosomal protein, large, P1 | -0.0274145 |
| RAB7A | RAB7A, member RAS oncogene family | -0.027392 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273499 |
| CD2AP | CD2-associated protein | -0.0270621 |
| GOLGB1 | golgin B1 | -0.0269882 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0268491 |
| HM13 | histocompatibility (minor) 13 | -0.0263225 |
| RPS24 | ribosomal protein S24 | -0.0261949 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0260266 |
| RPLP2 | ribosomal protein, large, P2 | -0.0259459 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0259378 |
| ACTG1 | actin gamma 1 | -0.0259315 |
| THOC2 | THO complex 2 | -0.0258143 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0252199 |
| TPM4 | tropomyosin 4 | -0.024775 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0246891 |
| RPL28 | ribosomal protein L28 | -0.0245549 |
| SP100 | SP100 nuclear antigen | -0.0244256 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0244207 |
| RPL12 | ribosomal protein L12 | -0.0241089 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0240187 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0238999 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0237437 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0235567 |
| FBXO11 | F-box protein 11 | -0.0233514 |
| AHNAK | AHNAK nucleoprotein | -0.0231514 |
| ETV6 | ets variant 6 | -0.0231338 |
| CTSD | cathepsin D | -0.0230772 |
| RPL37A | ribosomal protein L37a | -0.0228585 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0227951 |
| RIGI | RNA sensor RIG-I | -0.0226383 |
| PERP | PERP, TP53 apoptosis effector | -0.0226126 |
| NRP1 | neuropilin 1 | -0.0225803 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0222111 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0222089 |
| MYOF | myoferlin | -0.0221507 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0220931 |
| VCL | vinculin | -0.0218946 |
| RPS19 | ribosomal protein S19 | -0.0217985 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0216957 |
