| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.158329 |
| COL5A1 | collagen, type V, alpha 1 | 0.149145 |
| CDH13 | cadherin 13 | 0.147149 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.133952 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.104783 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0988225 |
| FN1 | fibronectin 1 | 0.0886336 |
| AHNAK | AHNAK nucleoprotein | 0.0841854 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0827088 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0736631 |
| NAV1 | neuron navigator 1 | 0.0714291 |
| EGFR | epidermal growth factor receptor | 0.0708655 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0650304 |
| FLNA | filamin A, alpha | 0.0600645 |
| MSI2 | musashi RNA-binding protein 2 | 0.0588384 |
| MAP1B | microtubule-associated protein 1B | 0.0572787 |
| NAV2 | neuron navigator 2 | 0.0572737 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0548318 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0540933 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.052084 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0508844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0493436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0493292 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0488186 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0481338 |
| EFNA5 | ephrin-A5 | 0.0474097 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0471997 |
| DST | dystonin | 0.0470422 |
| MYOF | myoferlin | 0.0457934 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0454 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0429358 |
| SEPTIN9 | septin 9 | 0.0422223 |
| HDAC9 | histone deacetylase 9 | 0.0407031 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0390328 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0385262 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0384357 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0380375 |
| RUNX1 | runt-related transcription factor 1 | 0.0377685 |
| CANX | calnexin | 0.0368504 |
| MSN | moesin | 0.0363608 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0358189 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0358187 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0357059 |
| CUX1 | cut-like homeobox 1 | 0.0354076 |
| DCLK2 | doublecortin-like kinase 2 | 0.0353648 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.034978 |
| FSTL1 | follistatin-like 1 | 0.0341174 |
| RNF213 | ring finger protein 213 | 0.0338102 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0329613 |
| RIGI | RNA sensor RIG-I | 0.032923 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0326978 |
| PLEC | plectin | 0.0326899 |
| PODXL | podocalyxin-like | 0.0325106 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0323587 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.032277 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0322254 |
| PRELID2 | PRELI domain containing 2 | 0.0321076 |
| RND3 | Rho family GTPase 3 | 0.0313021 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0302926 |
| CALR | calreticulin | 0.0302184 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0295686 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0291745 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0290116 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0285321 |
| COPA | coatomer protein complex, subunit alpha | 0.0284706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0281217 |
| POTEF | POTE ankyrin domain family, member F | 0.0278935 |
| C1D | C1D nuclear receptor corepressor | 0.0277786 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0277024 |
| PLXNA2 | plexin A2 | 0.0275218 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0272167 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0270926 |
| DSPP | dentin sialophosphoprotein | 0.0269921 |
| PFKP | phosphofructokinase, platelet | 0.0268504 |
| DENND1A | DENN/MADD domain containing 1A | 0.0262322 |
| AUTS2 | autism susceptibility candidate 2 | 0.0259199 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0256676 |
| SUCNR1 | succinate receptor 1 | 0.0256196 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0254928 |
| PRKCE | protein kinase C, epsilon | 0.0247334 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0246515 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0246091 |
| FLT1 | fms-related tyrosine kinase 1 | 0.024393 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0243623 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.024286 |
| TPM3 | tropomyosin 3 | 0.0242638 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0240992 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0238145 |
| COL5A2 | collagen, type V, alpha 2 | 0.0235194 |
| CYTH3 | cytohesin 3 | 0.0233945 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0232633 |
| PDE10A | phosphodiesterase 10A | 0.0231714 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0227351 |
| L1CAM | L1 cell adhesion molecule | 0.0225012 |
| PCDH7 | protocadherin 7 | 0.0224407 |
| ASPH | aspartate beta-hydroxylase | 0.022348 |
| FMN2 | formin 2 | 0.0216531 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.021503 |
| MMP12 | matrix metallopeptidase 12 | 0.0214942 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.021435 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.196538 |
| TMSB10 | thymosin beta 10 | -0.180875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168753 |
| B2M | beta-2-microglobulin | -0.101956 |
| VIM | vimentin | -0.0999831 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0996568 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0920458 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0764018 |
| HLA-B | major histocompatibility complex, class I, B | -0.0756763 |
| PTMA | prothymosin, alpha | -0.0715964 |
| FBN1 | fibrillin 1 | -0.0653202 |
| LOX | lysyl oxidase | -0.0619126 |
| S100A6 | S100 calcium binding protein A6 | -0.0560542 |
| FTL | ferritin, light polypeptide | -0.0534625 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0532633 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479078 |
| COL1A2 | collagen, type I, alpha 2 | -0.0472921 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0453996 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0431897 |
| NDRG1 | N-myc downstream regulated 1 | -0.0420195 |
| STC1 | stanniocalcin 1 | -0.0407097 |
| CSTB | cystatin B (stefin B) | -0.0385466 |
| RPL37A | ribosomal protein L37a | -0.0367416 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0365308 |
| COL3A1 | collagen, type III, alpha 1 | -0.0359061 |
| RPL23 | ribosomal protein L23 | -0.0353882 |
| RPL35A | ribosomal protein L35a | -0.0353825 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0350213 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0337693 |
| UBC | ubiquitin C | -0.033505 |
| CD44 | CD44 molecule (Indian blood group) | -0.033183 |
| S100A11 | S100 calcium binding protein A11 | -0.0331806 |
| RPS3 | ribosomal protein S3 | -0.0329527 |
| ANXA2 | annexin A2 | -0.0326141 |
| RPL12 | ribosomal protein L12 | -0.0322925 |
| HLA-C | major histocompatibility complex, class I, C | -0.0320853 |
| RPL31 | ribosomal protein L31 | -0.0314013 |
| S100A10 | S100 calcium binding protein A10 | -0.0308149 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0300521 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0298915 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296753 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0282176 |
| RPS19 | ribosomal protein S19 | -0.0279694 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0275067 |
| RPS8 | ribosomal protein S8 | -0.0274718 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0270614 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0266107 |
| RAI14 | retinoic acid induced 14 | -0.0264123 |
| PLAT | plasminogen activator, tissue | -0.0262456 |
| HLA-E | major histocompatibility complex, class I, E | -0.0261523 |
| CAVIN1 | caveolae associated protein 1 | -0.0259536 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259462 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0258221 |
| RPS6 | ribosomal protein S6 | -0.0256234 |
| LDHA | lactate dehydrogenase A | -0.0251875 |
| RPL26 | ribosomal protein L26 | -0.0248755 |
| RPL36 | ribosomal protein L36 | -0.0248268 |
| GLIS3 | GLIS family zinc finger 3 | -0.0247294 |
| RPS24 | ribosomal protein S24 | -0.0246406 |
| RPS12 | ribosomal protein S12 | -0.0245345 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0241771 |
| RACK1 | receptor for activated C kinase 1 | -0.0241727 |
| RPS27A | ribosomal protein S27a | -0.0239105 |
| RPL19 | ribosomal protein L19 | -0.0237649 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0236 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0229961 |
| RPL9 | ribosomal protein L9 | -0.0228892 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227392 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225058 |
| MYADM | myeloid-associated differentiation marker | -0.022015 |
| RPS13 | ribosomal protein S13 | -0.0219253 |
| RPS14 | ribosomal protein S14 | -0.0215552 |
| SEC61G | Sec61 gamma subunit | -0.0215429 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0208823 |
| RPL34 | ribosomal protein L34 | -0.0208656 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0206296 |
| H3-3B | H3.3 histone B | -0.0205767 |
| RPL37 | ribosomal protein L37 | -0.0205721 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.020426 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0197912 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0196989 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0193463 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.019174 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0191415 |
| FAM162A | family with sequence similarity 162, member A | -0.0191191 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0189882 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0189158 |
| RPLP0 | ribosomal protein, large, P0 | -0.0188804 |
| PDCD5 | programmed cell death 5 | -0.018806 |
| KLF6 | Kruppel-like factor 6 | -0.0187438 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0182443 |
| RPS23 | ribosomal protein S23 | -0.0179289 |
| RPS15 | ribosomal protein S15 | -0.0178675 |
| RPS5 | ribosomal protein S5 | -0.0177793 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.017621 |
| RPL28 | ribosomal protein L28 | -0.0175663 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.0175487 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0175152 |
| RPL11 | ribosomal protein L11 | -0.0175109 |
| RPS17 | ribosomal protein S17 | -0.0173409 |
