| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.076619 |
| PCBP2 | poly(rC) binding protein 2 | 0.0400627 |
| TENM3 | teneurin transmembrane protein 3 | 0.0334971 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0310745 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0308652 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0265909 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0260905 |
| WWOX | WW domain containing oxidoreductase | 0.0260235 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.024201 |
| CCNL1 | cyclin L1 | 0.0241452 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0235252 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0224159 |
| ZNF292 | zinc finger protein 292 | 0.0203872 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0202161 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0201782 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0195575 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0193427 |
| RBM25 | RNA binding motif protein 25 | 0.0190968 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0190304 |
| NEBL | nebulette | 0.0189923 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0187531 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0177857 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0176603 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0174066 |
| YEATS2 | YEATS domain containing 2 | 0.0171169 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0170191 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0168264 |
| EPHA6 | EPH receptor A6 | 0.0166938 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0162358 |
| RSF1 | remodeling and spacing factor 1 | 0.0161188 |
| ATP11A | ATPase, class VI, type 11A | 0.0158353 |
| CCN2 | cellular communication network factor 2 | 0.0157098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0156949 |
| BRD2 | bromodomain containing 2 | 0.0156138 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0153111 |
| RNF213 | ring finger protein 213 | 0.0151693 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0148951 |
| TJP1 | tight junction protein 1 | 0.0148684 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0148157 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0144786 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0144142 |
| SON | SON DNA binding protein | 0.0142721 |
| FLNA | filamin A, alpha | 0.0140401 |
| YAP1 | Yes-associated protein 1 | 0.0136957 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0136715 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0136317 |
| POTEF | POTE ankyrin domain family, member F | 0.013625 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0136008 |
| WDR26 | WD repeat domain 26 | 0.0134385 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0134194 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0134119 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0133439 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0131225 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0129737 |
| HDAC4 | histone deacetylase 4 | 0.0127252 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0126987 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0126797 |
| HELZ | helicase with zinc finger | 0.0126577 |
| FHIT | fragile histidine triad | 0.0126347 |
| FUS | FUS RNA binding protein | 0.0126028 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0125478 |
| RRM2 | ribonucleotide reductase M2 | 0.0125408 |
| PCM1 | pericentriolar material 1 | 0.0125136 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0123856 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0122048 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.012141 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0120843 |
| RUNX1 | runt-related transcription factor 1 | 0.0119365 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.011923 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0118673 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0118591 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0117891 |
| ZNF638 | zinc finger protein 638 | 0.0117383 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0116483 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0115311 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0115174 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0114383 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0113769 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.011331 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0113203 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0112992 |
| DIAPH1 | diaphanous-related formin 1 | 0.0112849 |
| RAD51B | RAD51 paralog B | 0.0112769 |
| CABIN1 | calcineurin binding protein 1 | 0.011239 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0111275 |
| TPM3 | tropomyosin 3 | 0.0111131 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0108526 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.010816 |
| PRELID2 | PRELI domain containing 2 | 0.0107587 |
| NSUN2 | NOP2/Sun RNA methyltransferase family, member 2 | 0.0107037 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0106334 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0105588 |
| XPO1 | exportin 1 | 0.0105583 |
| POU2F1 | POU class 2 homeobox 1 | 0.0104178 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.010368 |
| EP400 | E1A binding protein p400 | 0.0103415 |
| TPR | translocated promoter region, nuclear basket protein | 0.0103216 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0102923 |
| PTMS | parathymosin | 0.010289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.251648 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.240206 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.169947 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0768673 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0752823 |
| TMSB10 | thymosin beta 10 | -0.0716511 |
| PTMA | prothymosin, alpha | -0.07093 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659909 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0641714 |
| HMGA2 | high mobility group AT-hook 2 | -0.0616545 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0516991 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0470771 |
| RPS8 | ribosomal protein S8 | -0.0469617 |
| ANXA1 | annexin A1 | -0.0447885 |
| MMP12 | matrix metallopeptidase 12 | -0.0447438 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0430425 |
| RPL26 | ribosomal protein L26 | -0.0413769 |
| TMEM41B | transmembrane protein 41B | -0.0409081 |
| RPLP0 | ribosomal protein, large, P0 | -0.0398379 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.039358 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0392416 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0391583 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0390732 |
| CLDN1 | claudin 1 | -0.0376558 |
| S100A6 | S100 calcium binding protein A6 | -0.0375135 |
| RASAL2 | RAS protein activator like 2 | -0.0372842 |
| RPS3 | ribosomal protein S3 | -0.0366205 |
| ACTG1 | actin gamma 1 | -0.0362752 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0360649 |
| JMJD1C | jumonji domain containing 1C | -0.0359771 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0358219 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0341871 |
| RPS24 | ribosomal protein S24 | -0.0341395 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0334989 |
| FTL | ferritin, light polypeptide | -0.0334407 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0332265 |
| AREG | amphiregulin | -0.0328238 |
| RPL35A | ribosomal protein L35a | -0.0319137 |
| EHBP1 | EH domain binding protein 1 | -0.031443 |
| LMO7 | LIM domain 7 | -0.0312195 |
| RPL34 | ribosomal protein L34 | -0.0308803 |
| GNAS | GNAS complex locus | -0.0307554 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0305 |
| TMEM123 | transmembrane protein 123 | -0.0302762 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.029655 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0296521 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0283809 |
| S100A10 | S100 calcium binding protein A10 | -0.0282308 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0270444 |
| RPLP1 | ribosomal protein, large, P1 | -0.0269529 |
| KLF6 | Kruppel-like factor 6 | -0.0268048 |
| RACK1 | receptor for activated C kinase 1 | -0.0265372 |
| ZNF804A | zinc finger protein 804A | -0.0259145 |
| TPI1 | triosephosphate isomerase 1 | -0.0258812 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0258087 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0256881 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0254028 |
| RPL11 | ribosomal protein L11 | -0.0253456 |
| GCG | glucagon | -0.0252049 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0251806 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0249162 |
| PDGFC | platelet derived growth factor C | -0.0248984 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0246676 |
| RPL12 | ribosomal protein L12 | -0.0246418 |
| ENO1 | enolase 1, (alpha) | -0.0245364 |
| RPL19 | ribosomal protein L19 | -0.0241525 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235512 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0234599 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0234429 |
| RPS12 | ribosomal protein S12 | -0.0232891 |
| RAB10 | RAB10, member RAS oncogene family | -0.0232445 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0232196 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0227001 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0226005 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0225719 |
| RPS13 | ribosomal protein S13 | -0.0225335 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0225054 |
| RPS16 | ribosomal protein S16 | -0.0223026 |
| TUBA1B | tubulin, alpha 1b | -0.0219006 |
| RPS27A | ribosomal protein S27a | -0.0218741 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0217942 |
| RPL37 | ribosomal protein L37 | -0.0216584 |
| ASPH | aspartate beta-hydroxylase | -0.0213862 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0209693 |
| CCND1 | cyclin D1 | -0.0209491 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0206086 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0205832 |
| RPS2 | ribosomal protein S2 | -0.0205175 |
| CDK17 | cyclin-dependent kinase 17 | -0.020155 |
| RPL38 | ribosomal protein L38 | -0.0200151 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0194153 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0191875 |
| RPL23 | ribosomal protein L23 | -0.019043 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0190347 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0189766 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0188545 |
| BCHE | butyrylcholinesterase | -0.0183683 |
| NHSL1 | NHS-like 1 | -0.0183303 |
| TPM4 | tropomyosin 4 | -0.0179835 |
| IL6ST | interleukin 6 signal transducer | -0.0179365 |