| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.10773 |
| VIM | vimentin | 0.0990818 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0960427 |
| ACTG1 | actin gamma 1 | 0.0921743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.083193 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0808586 |
| KRT81 | keratin 81, type II | 0.0766251 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0691153 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.067833 |
| AUTS2 | autism susceptibility candidate 2 | 0.0667756 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0664615 |
| PRKCA | protein kinase C, alpha | 0.0661955 |
| POTEF | POTE ankyrin domain family, member F | 0.0633114 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0578404 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0573575 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0556589 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0555345 |
| EGFR | epidermal growth factor receptor | 0.0548573 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0546278 |
| HMGA2 | high mobility group AT-hook 2 | 0.0532628 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.05237 |
| MCL1 | myeloid cell leukemia 1 | 0.0522513 |
| MYO1E | myosin IE | 0.0519583 |
| TPM4 | tropomyosin 4 | 0.051039 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0504785 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0488402 |
| FBXO11 | F-box protein 11 | 0.0480164 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.0477781 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0469641 |
| EFNA5 | ephrin-A5 | 0.0468524 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0463925 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461892 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0453908 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.045328 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0441027 |
| PLEC | plectin | 0.0440298 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0438038 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0435072 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0434455 |
| MAP1B | microtubule-associated protein 1B | 0.042636 |
| FLNA | filamin A, alpha | 0.0420778 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0399 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0393713 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0392343 |
| S100A6 | S100 calcium binding protein A6 | 0.0391774 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0391548 |
| NRG1 | neuregulin 1 | 0.0386595 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0385267 |
| S100A10 | S100 calcium binding protein A10 | 0.03788 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0369819 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0368423 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0367319 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0365242 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0364653 |
| ZFHX3 | zinc finger homeobox 3 | 0.0361284 |
| CTBP2 | C-terminal binding protein 2 | 0.0361166 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0360918 |
| SQSTM1 | sequestosome 1 | 0.0360605 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0357974 |
| PALLD | palladin, cytoskeletal associated protein | 0.0352181 |
| CCDC88A | coiled-coil domain containing 88A | 0.0349087 |
| CALU | calumenin | 0.0345776 |
| JMJD1C | jumonji domain containing 1C | 0.0343587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336112 |
| FLNB | filamin B, beta | 0.0332455 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0330669 |
| TPM1 | tropomyosin 1 (alpha) | 0.0330297 |
| EHBP1 | EH domain binding protein 1 | 0.0329439 |
| LMNA | lamin A/C | 0.0322736 |
| FUS | FUS RNA binding protein | 0.0321857 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0319779 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0317609 |
| INTS6 | integrator complex subunit 6 | 0.0314214 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0312924 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0312376 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0305411 |
| MYO10 | myosin X | 0.0300022 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0299821 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0295187 |
| ASPH | aspartate beta-hydroxylase | 0.0293817 |
| ADM | adrenomedullin | 0.0292045 |
| USP47 | ubiquitin specific peptidase 47 | 0.0291763 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0291082 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0289308 |
| NDRG1 | N-myc downstream regulated 1 | 0.0288275 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0284575 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0283179 |
| TNS1 | tensin 1 | 0.0283094 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0283038 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0282298 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0277507 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.02769 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0274919 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0272828 |
| SETX | senataxin | 0.0271263 |
| MED13L | mediator complex subunit 13-like | 0.0269992 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.026829 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0268234 |
| DUSP16 | dual specificity phosphatase 16 | 0.0266631 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0262959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.230432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.148616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13695 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.127961 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.101918 |
| MT2A | metallothionein 2A | -0.0986327 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0946527 |
| FTL | ferritin, light polypeptide | -0.0816282 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0785488 |
| RPS19 | ribosomal protein S19 | -0.0596353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0566709 |
| KYNU | kynureninase | -0.0526429 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.051009 |
| RPS3 | ribosomal protein S3 | -0.0492298 |
| RPL23 | ribosomal protein L23 | -0.0489893 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0486132 |
| RPS2 | ribosomal protein S2 | -0.0476156 |
| PDE10A | phosphodiesterase 10A | -0.0473707 |
| RPL26 | ribosomal protein L26 | -0.04695 |
| STC1 | stanniocalcin 1 | -0.0462172 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0459256 |
| RPL12 | ribosomal protein L12 | -0.0456636 |
| NCOA7 | nuclear receptor coactivator 7 | -0.042597 |
| TGM2 | transglutaminase 2 | -0.0422875 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0408931 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0406235 |
| RACK1 | receptor for activated C kinase 1 | -0.0400431 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0395601 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0374272 |
| RPS12 | ribosomal protein S12 | -0.0373037 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0372846 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.036438 |
| TXNRD1 | thioredoxin reductase 1 | -0.036088 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0356169 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0353466 |
| RPL28 | ribosomal protein L28 | -0.0347117 |
| RPL19 | ribosomal protein L19 | -0.0334144 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0330807 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0328145 |
| LDHA | lactate dehydrogenase A | -0.0320932 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0320852 |
| RPS5 | ribosomal protein S5 | -0.0319269 |
| AOPEP | aminopeptidase O (putative) | -0.0318708 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0316541 |
| EREG | epiregulin | -0.0313787 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0311818 |
| RIGI | RNA sensor RIG-I | -0.0311804 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0306222 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0306015 |
| RPLP0 | ribosomal protein, large, P0 | -0.0305479 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305262 |
| TDRD7 | tudor domain containing 7 | -0.0299976 |
| OSMR | oncostatin M receptor | -0.0295495 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0290277 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0286441 |
| RPL4 | ribosomal protein L4 | -0.028612 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0281344 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.028006 |
| MT1X | metallothionein 1X | -0.0279205 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0276522 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.027526 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0270527 |
| ANGPTL4 | angiopoietin-like 4 | -0.026564 |
| RPS27 | ribosomal protein S27 | -0.0264309 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0264228 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0259128 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258979 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0253499 |
| KIAA1217 | KIAA1217 | -0.0247433 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0243377 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0242496 |
| RPL31 | ribosomal protein L31 | -0.0240273 |
| PDZD8 | PDZ domain containing 8 | -0.0233412 |
| CDC42SE2 | CDC42 small effector 2 | -0.0232333 |
| RAI14 | retinoic acid induced 14 | -0.022816 |
| NUP58 | nucleoporin 58 | -0.0227615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0227308 |
| HELZ | helicase with zinc finger | -0.0226089 |
| ZNF292 | zinc finger protein 292 | -0.0225851 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0223333 |
| JAK1 | Janus kinase 1 | -0.0221079 |
| RASA2 | RAS p21 protein activator 2 | -0.0219118 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0218966 |
| DENND4C | DENN/MADD domain containing 4C | -0.0216966 |
| RIN2 | Ras and Rab interactor 2 | -0.0212968 |
| MX1 | MX dynamin-like GTPase 1 | -0.0212614 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0211273 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0210566 |
| RPS17 | ribosomal protein S17 | -0.021031 |
| LDHB | lactate dehydrogenase B | -0.0206631 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0206569 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0206541 |
| GPRIN3 | GPRIN family member 3 | -0.0206392 |
| TKT | transketolase | -0.0205655 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0205035 |
| USP3 | ubiquitin specific peptidase 3 | -0.020422 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0202926 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0202507 |
| GPC6 | glypican 6 | -0.0201811 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0201747 |
