| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.158461 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.14118 |
| HMGA2 | high mobility group AT-hook 2 | 0.0753591 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0732631 |
| CTBP2 | C-terminal binding protein 2 | 0.064571 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0639526 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0635082 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0630819 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0621837 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0567627 |
| PDE10A | phosphodiesterase 10A | 0.0549377 |
| GSE1 | Gse1 coiled-coil protein | 0.0525477 |
| DENND1A | DENN/MADD domain containing 1A | 0.050401 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0500591 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0493246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473031 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.047184 |
| OGA | O-GlcNAcase | 0.0443178 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0442096 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0435252 |
| NFIB | nuclear factor I/B | 0.0426317 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0424275 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0421639 |
| CADM2 | cell adhesion molecule 2 | 0.0416722 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0414594 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0400163 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0398615 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0390145 |
| MYOF | myoferlin | 0.0382937 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0380159 |
| RANBP17 | RAN binding protein 17 | 0.0380013 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377043 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0375575 |
| CUX1 | cut-like homeobox 1 | 0.0373812 |
| ZFHX3 | zinc finger homeobox 3 | 0.0373521 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0373398 |
| SBF2 | SET binding factor 2 | 0.036823 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0367712 |
| AHNAK | AHNAK nucleoprotein | 0.0365797 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0363443 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0361367 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0359715 |
| FOXN3 | forkhead box N3 | 0.0354117 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0352784 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0331801 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0321352 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0321318 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0320096 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0318364 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0313027 |
| FMNL2 | formin-like 2 | 0.0312216 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0306943 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0306081 |
| VCL | vinculin | 0.0303413 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0302395 |
| ANO6 | anoctamin 6 | 0.0300436 |
| TCF12 | transcription factor 12 | 0.0300144 |
| FUS | FUS RNA binding protein | 0.0296976 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0287015 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0285808 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0285759 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283901 |
| INTS6 | integrator complex subunit 6 | 0.0278358 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0278086 |
| CCNY | cyclin Y | 0.0277543 |
| KAZN | kazrin, periplakin interacting protein | 0.0277464 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0276988 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0275724 |
| NFIA | nuclear factor I/A | 0.0275667 |
| E2F3 | E2F transcription factor 3 | 0.0272354 |
| PRELID2 | PRELI domain containing 2 | 0.0272115 |
| SLMAP | sarcolemma associated protein | 0.0270713 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0270584 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0269118 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0267251 |
| TFRC | transferrin receptor | 0.0265515 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0263101 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0262388 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0261791 |
| TULP4 | tubby like protein 4 | 0.0260154 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0259567 |
| ZNF608 | zinc finger protein 608 | 0.0259147 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0258924 |
| MCU | mitochondrial calcium uniporter | 0.0256004 |
| PARD3 | par-3 family cell polarity regulator | 0.0254975 |
| ECT2 | epithelial cell transforming 2 | 0.0254846 |
| CENPE | centromere protein E, 312kDa | 0.0254481 |
| PTK2 | protein tyrosine kinase 2 | 0.0254338 |
| MSI2 | musashi RNA-binding protein 2 | 0.0254003 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.025198 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0250413 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0247471 |
| EXOC4 | exocyst complex component 4 | 0.0246965 |
| CUL1 | cullin 1 | 0.0245285 |
| CMIP | c-Maf inducing protein | 0.0243496 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0242705 |
| IPO7 | importin 7 | 0.024195 |
| HDAC8 | histone deacetylase 8 | 0.0241653 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0240169 |
| ATP11A | ATPase, class VI, type 11A | 0.0240029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.444882 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0859456 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0784052 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.077545 |
| RPS6 | ribosomal protein S6 | -0.0616882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0554645 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0496783 |
| IGF2 | insulin-like growth factor 2 | -0.0481287 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0464616 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0413549 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0392219 |
| EGR1 | early growth response 1 | -0.039025 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387841 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0379882 |
| VIM | vimentin | -0.0379232 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0357654 |
| RPS2 | ribosomal protein S2 | -0.0355083 |
| YBX1 | Y box binding protein 1 | -0.0347771 |
| POTEF | POTE ankyrin domain family, member F | -0.0317335 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.031265 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0306698 |
| PFN1 | profilin 1 | -0.0303763 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0302059 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0301413 |
| RTN4 | reticulon 4 | -0.0280217 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0278807 |
| LDHA | lactate dehydrogenase A | -0.0276862 |
| TPM4 | tropomyosin 4 | -0.0271465 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.026549 |
| CALR | calreticulin | -0.0264651 |
| RNF145 | ring finger protein 145 | -0.0261068 |
| GNAS | GNAS complex locus | -0.0259918 |
| DSTN | destrin (actin depolymerizing factor) | -0.0259602 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0256316 |
| RBM39 | RNA binding motif protein 39 | -0.0252696 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0251779 |
| TMEM41B | transmembrane protein 41B | -0.0247591 |
| MSN | moesin | -0.0246094 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0244108 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0242057 |
| PTMA | prothymosin, alpha | -0.0241807 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.024028 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.023994 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0239435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.02387 |
| SRP54 | signal recognition particle 54kDa | -0.0227183 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0225523 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0218424 |
| NOP58 | NOP58 ribonucleoprotein | -0.0217471 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0217324 |
| PLS3 | plastin 3 | -0.0217286 |
| TAPBP | TAP binding protein (tapasin) | -0.0214799 |
| FTL | ferritin, light polypeptide | -0.0214291 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0212093 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0212039 |
| CLINT1 | clathrin interactor 1 | -0.0206516 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.020347 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0202794 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0202787 |
| EFNA5 | ephrin-A5 | -0.0202545 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0198827 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0197275 |
| RPL35 | ribosomal protein L35 | -0.0196423 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.019581 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0195099 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0193653 |
| USP3 | ubiquitin specific peptidase 3 | -0.0193492 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0193373 |
| CBX1 | chromobox homolog 1 | -0.0191475 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0191109 |
| PEG10 | paternally expressed 10 | -0.0189332 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0188984 |
| ASPH | aspartate beta-hydroxylase | -0.018845 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0187115 |
| WDR45B | WD repeat domain 45B | -0.0186443 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0184244 |
| RPL10A | ribosomal protein L10a | -0.0183503 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0182714 |
| SEC24A | SEC24 family member A | -0.0180983 |
| PCBP2 | poly(rC) binding protein 2 | -0.0179984 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0179862 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0178804 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0177782 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0177597 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0176282 |
| SET | SET nuclear proto-oncogene | -0.0175972 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0174735 |
| KIF3B | kinesin family member 3B | -0.017393 |
| PTMS | parathymosin | -0.0172666 |
| NUP58 | nucleoporin 58 | -0.0172601 |
| PCM1 | pericentriolar material 1 | -0.0172184 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0172029 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0171247 |
| SEC24D | SEC24 family member D | -0.0170367 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0170361 |
| CBX3 | chromobox homolog 3 | -0.0169457 |
| RPL4 | ribosomal protein L4 | -0.0168949 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0166475 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0165663 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0164252 |
