| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0717275 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0383127 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0338727 |
| VCL | vinculin | 0.0326956 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0316621 |
| PLEC | plectin | 0.0307454 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0286025 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0258184 |
| LAMC2 | laminin, gamma 2 | 0.0255377 |
| CAB39 | calcium binding protein 39 | 0.0238403 |
| TGFA | transforming growth factor, alpha | 0.0232092 |
| BCL2L1 | BCL2-like 1 | 0.0232069 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.022079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.021026 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0184465 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0183215 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0176785 |
| RASAL2 | RAS protein activator like 2 | 0.0161739 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0161657 |
| CORO1C | coronin, actin binding protein, 1C | 0.0155015 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0154442 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0153103 |
| BLCAP | bladder cancer associated protein | 0.0153067 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0150301 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0149638 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0147413 |
| LAMA4 | laminin, alpha 4 | 0.0146821 |
| NABP1 | nucleic acid binding protein 1 | 0.0144914 |
| FLNA | filamin A, alpha | 0.0144407 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0141447 |
| CDK13 | cyclin-dependent kinase 13 | 0.0137288 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0134845 |
| SEPTIN9 | septin 9 | 0.0134318 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0130166 |
| FUS | FUS RNA binding protein | 0.0128447 |
| NPAS2 | neuronal PAS domain protein 2 | 0.012613 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0125991 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0123139 |
| THBD | thrombomodulin | 0.0122827 |
| PMM2 | phosphomannomutase 2 | 0.0122739 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0122293 |
| IL6ST | interleukin 6 signal transducer | 0.0120345 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0120208 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0119696 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0118774 |
| MOSMO | modulator of smoothened | 0.0117415 |
| RIGI | RNA sensor RIG-I | 0.0117408 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0115497 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0114766 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0113558 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0113521 |
| ZNF83 | zinc finger protein 83 | 0.01134 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0113211 |
| STRIP2 | striatin interacting protein 2 | 0.0113015 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0111769 |
| FOXO3 | forkhead box O3 | 0.0111587 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0110412 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0109796 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0107754 |
| XPO6 | exportin 6 | 0.0105689 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0104958 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0104674 |
| MYO9B | myosin IXB | 0.0102916 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0102373 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0100596 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0100223 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0100096 |
| TUFT1 | tuftelin 1 | 0.00999365 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00996347 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.00995971 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0099018 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.00989646 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.00988252 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00987195 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00984155 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.00982564 |
| DENND2C | DENN/MADD domain containing 2C | 0.00970846 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00968177 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00967078 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00954085 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.00937879 |
| SAFB2 | scaffold attachment factor B2 | 0.00937743 |
| TASOR2 | transcription activation suppressor family member 2 | 0.00936517 |
| CFAP161 | cilia and flagella associated protein 161 | 0.00933742 |
| HMGA2 | high mobility group AT-hook 2 | 0.00930067 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00895886 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00884313 |
| AFDN | afadin, adherens junction formation factor | 0.00882902 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00882009 |
| GDA | guanine deaminase | 0.00881746 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.00877441 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00869834 |
| SAV1 | salvador family WW domain containing protein 1 | 0.00865095 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.00864039 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.00863539 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00859241 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.00856607 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00856383 |
| MYO19 | myosin XIX | 0.00855449 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00853755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.210369 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.180056 |
| TMSB10 | thymosin beta 10 | -0.179702 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172487 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.169891 |
| VIM | vimentin | -0.162576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.151809 |
| NDRG1 | N-myc downstream regulated 1 | -0.148004 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.118528 |
| EZR | ezrin | -0.102534 |
| HMGA1 | high mobility group AT-hook 1 | -0.0940116 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0914441 |
| PTMA | prothymosin, alpha | -0.0883189 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0881763 |
| RIOK3 | RIO kinase 3 | -0.0879725 |
| LDHA | lactate dehydrogenase A | -0.0794879 |
| MUC17 | mucin 17, cell surface associated | -0.0757647 |
| FLNB | filamin B, beta | -0.0757502 |
| TXNIP | thioredoxin interacting protein | -0.0749545 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0748515 |
| POTEF | POTE ankyrin domain family, member F | -0.0732697 |
| UBC | ubiquitin C | -0.0726463 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0705448 |
| S100A10 | S100 calcium binding protein A10 | -0.0692728 |
| TXNRD1 | thioredoxin reductase 1 | -0.0684173 |
| PGK1 | phosphoglycerate kinase 1 | -0.0681279 |
| FAM107B | family with sequence similarity 107, member B | -0.0678774 |
| EGFR | epidermal growth factor receptor | -0.0651224 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0648175 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0644541 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0642467 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0642302 |
| S100A11 | S100 calcium binding protein A11 | -0.0612587 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0596334 |
| EGR1 | early growth response 1 | -0.0589738 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0581866 |
| B2M | beta-2-microglobulin | -0.0575048 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0574154 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0546525 |
| FTL | ferritin, light polypeptide | -0.0543042 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0538253 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0527026 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0524921 |
| MXD1 | MAX dimerization protein 1 | -0.0519129 |
| RPS3 | ribosomal protein S3 | -0.0517968 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.051432 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0505595 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0503204 |
| PKM | pyruvate kinase, muscle | -0.0493732 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0490681 |
| TPM3 | tropomyosin 3 | -0.0480751 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0467025 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0459028 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0454479 |
| DIAPH1 | diaphanous-related formin 1 | -0.045144 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0445958 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0437784 |
| S100A6 | S100 calcium binding protein A6 | -0.0433575 |
| ANXA2 | annexin A2 | -0.0432616 |
| WASF2 | WAS protein family, member 2 | -0.0427846 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0424219 |
| EFNA5 | ephrin-A5 | -0.0422667 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.041555 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.041287 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0411778 |
| DSPP | dentin sialophosphoprotein | -0.0411189 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0407412 |
| MORF4L2 | mortality factor 4 like 2 | -0.0401069 |
| RACK1 | receptor for activated C kinase 1 | -0.039096 |
| RPS27 | ribosomal protein S27 | -0.0383781 |
| RPS6 | ribosomal protein S6 | -0.0382285 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0381693 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0379566 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0370244 |
| RPL12 | ribosomal protein L12 | -0.0367822 |
| RPLP1 | ribosomal protein, large, P1 | -0.0365614 |
| RPS8 | ribosomal protein S8 | -0.0365263 |
| FAM13A | family with sequence similarity 13, member A | -0.0364741 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0361086 |
| ENO1 | enolase 1, (alpha) | -0.0357986 |
| RPS12 | ribosomal protein S12 | -0.0353419 |
| EMP1 | epithelial membrane protein 1 | -0.0350996 |
| GOLGA4 | golgin A4 | -0.0348608 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.034719 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0343731 |
| SPAG9 | sperm associated antigen 9 | -0.0341334 |
| RAB1A | RAB1A, member RAS oncogene family | -0.033714 |
| PCBP2 | poly(rC) binding protein 2 | -0.0336746 |
| CDCP1 | CUB domain containing protein 1 | -0.0332243 |
| OPTN | optineurin | -0.0331695 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0330201 |
| ARF4 | ADP-ribosylation factor 4 | -0.0327772 |
| RPL31 | ribosomal protein L31 | -0.0327108 |
| DSG2 | desmoglein 2 | -0.032037 |
| RPL8 | ribosomal protein L8 | -0.0318026 |
| RPL37A | ribosomal protein L37a | -0.0316385 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0316306 |
| RPS14 | ribosomal protein S14 | -0.0313655 |
| RPL23 | ribosomal protein L23 | -0.0311206 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311119 |
