| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123347 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0908389 |
| CALU | calumenin | 0.0808645 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0703451 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0648306 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0605467 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0530977 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0516969 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0491426 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0462269 |
| FMNL2 | formin-like 2 | 0.0455174 |
| NAV2 | neuron navigator 2 | 0.0449575 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0442074 |
| NAV1 | neuron navigator 1 | 0.0434757 |
| CUX1 | cut-like homeobox 1 | 0.0430373 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0420823 |
| SEPTIN9 | septin 9 | 0.0404269 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0403668 |
| ACTN1 | actinin, alpha 1 | 0.0381722 |
| COPA | coatomer protein complex, subunit alpha | 0.0368513 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0361776 |
| AHNAK | AHNAK nucleoprotein | 0.0360976 |
| TLE4 | transducin-like enhancer of split 4 | 0.0355897 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0352996 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0349148 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0344117 |
| CABIN1 | calcineurin binding protein 1 | 0.0338401 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0337376 |
| FUS | FUS RNA binding protein | 0.0334032 |
| PLEC | plectin | 0.0329978 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.032931 |
| CTBP2 | C-terminal binding protein 2 | 0.032457 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0324263 |
| LMNA | lamin A/C | 0.0321659 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0320276 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0320127 |
| RASA3 | RAS p21 protein activator 3 | 0.0318573 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0315253 |
| MYO1E | myosin IE | 0.0314466 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0312944 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0312166 |
| ATXN1 | ataxin 1 | 0.0311632 |
| EGR1 | early growth response 1 | 0.0307329 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0306094 |
| FLNB | filamin B, beta | 0.0304628 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0301147 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0299385 |
| IGF1R | insulin-like growth factor 1 receptor | 0.029885 |
| PTK2 | protein tyrosine kinase 2 | 0.0298557 |
| SETBP1 | SET binding protein 1 | 0.0298332 |
| INTS6 | integrator complex subunit 6 | 0.0298118 |
| CALR | calreticulin | 0.0297516 |
| SKI | SKI proto-oncogene | 0.0291911 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0291757 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0290891 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0286897 |
| PARVB | parvin, beta | 0.0286117 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0285951 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0285465 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0285232 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0280764 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0269669 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0269043 |
| LRRC23 | leucine rich repeat containing 23 | 0.0264675 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0259752 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0253606 |
| WDR1 | WD repeat domain 1 | 0.0253558 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0251229 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0250897 |
| HIP1 | huntingtin interacting protein 1 | 0.0250565 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0249769 |
| TPR | translocated promoter region, nuclear basket protein | 0.0248865 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0247031 |
| AFDN | afadin, adherens junction formation factor | 0.0242449 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0240893 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0236531 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0236014 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0234687 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0226389 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0225638 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0223728 |
| PAX3 | paired box 3 | 0.0223446 |
| FLNA | filamin A, alpha | 0.0222439 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0222192 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0221536 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219818 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0218827 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0216673 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216071 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0214329 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0212272 |
| TFRC | transferrin receptor | 0.0211122 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0210153 |
| CANX | calnexin | 0.0205829 |
| COG5 | component of oligomeric golgi complex 5 | 0.0204053 |
| UBE3C | ubiquitin protein ligase E3C | 0.0203295 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0203229 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0202188 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0199819 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0199187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.137049 |
| NLGN1 | neuroligin 1 | -0.10073 |
| FN1 | fibronectin 1 | -0.0938951 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0813781 |
| GPC6 | glypican 6 | -0.0688135 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0669491 |
| VIM | vimentin | -0.0668731 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0591886 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0573214 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0547351 |
| AHR | aryl hydrocarbon receptor | -0.0526613 |
| TNNC1 | troponin C type 1 (slow) | -0.0496299 |
| MACROD2 | MACRO domain containing 2 | -0.0484988 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0472234 |
| DCT | dopachrome tautomerase | -0.047035 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0448063 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0428455 |
| OXR1 | oxidation resistance 1 | -0.040944 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0407689 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.039174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.039074 |
| RNF145 | ring finger protein 145 | -0.0368992 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0364182 |
| POTEF | POTE ankyrin domain family, member F | -0.036017 |
| ENO1 | enolase 1, (alpha) | -0.035821 |
| PCDH7 | protocadherin 7 | -0.0353253 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0349738 |
| ZNF292 | zinc finger protein 292 | -0.0344671 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0340375 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0331421 |
| TMSB10 | thymosin beta 10 | -0.0329383 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329264 |
| TAGLN2 | transgelin 2 | -0.0323641 |
| PI15 | peptidase inhibitor 15 | -0.0314047 |
| FRMD4A | FERM domain containing 4A | -0.0309612 |
| S100A6 | S100 calcium binding protein A6 | -0.0305627 |
| CALD1 | caldesmon 1 | -0.0298466 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0288481 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0286058 |
| PHF21A | PHD finger protein 21A | -0.0282825 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0278205 |
| RTN4 | reticulon 4 | -0.0276807 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0273366 |
| CENPF | centromere protein F, 350/400kDa | -0.0269135 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.025873 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0255599 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0248421 |
| CD109 | CD109 molecule | -0.0242007 |
| A2M | alpha-2-macroglobulin | -0.0232806 |
| MT2A | metallothionein 2A | -0.0229844 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0229671 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0227257 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0220205 |
| PRKD1 | protein kinase D1 | -0.0217093 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0208655 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0208122 |
| B2M | beta-2-microglobulin | -0.0207957 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0204408 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0201268 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0199185 |
| NPC1 | Niemann-Pick disease, type C1 | -0.019842 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0187839 |
| RPS12 | ribosomal protein S12 | -0.0183702 |
| RAD51B | RAD51 paralog B | -0.0181231 |
| RNF24 | ring finger protein 24 | -0.0177185 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0174215 |
| PDE10A | phosphodiesterase 10A | -0.0174009 |
| RFX7 | regulatory factor X, 7 | -0.0170603 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0170357 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0169724 |
| FOSL1 | FOS-like antigen 1 | -0.0169701 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0167746 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0167693 |
| ASPH | aspartate beta-hydroxylase | -0.0164232 |
| MTPN | myotrophin | -0.0163467 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0162343 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0159745 |
| TBK1 | TANK-binding kinase 1 | -0.0157702 |
| FBXO7 | F-box protein 7 | -0.0156046 |
| HLA-A | major histocompatibility complex, class I, A | -0.0154367 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0153984 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0153673 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.01514 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0151072 |
| PLIN2 | perilipin 2 | -0.0150862 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0150599 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.015051 |
| FTL | ferritin, light polypeptide | -0.0149439 |
| FOXJ3 | forkhead box J3 | -0.0147923 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0146515 |
| UBXN4 | UBX domain protein 4 | -0.0145164 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0144098 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.014322 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0143015 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0142814 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0140475 |
| HLA-B | major histocompatibility complex, class I, B | -0.0138352 |
| RPS2 | ribosomal protein S2 | -0.013788 |
| TSPAN3 | tetraspanin 3 | -0.0137126 |
| CDH19 | cadherin 19, type 2 | -0.0136618 |