| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.151369 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0722038 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0716174 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0636012 |
| BRD2 | bromodomain containing 2 | 0.0559704 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0522354 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0511627 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0508539 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0472489 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0470142 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0421029 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0413347 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0412146 |
| PLEC | plectin | 0.0390753 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.035797 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353087 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0352877 |
| RPS2 | ribosomal protein S2 | 0.035231 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345008 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.032834 |
| TPM3 | tropomyosin 3 | 0.0326363 |
| PNN | pinin, desmosome associated protein | 0.0319883 |
| LAMC2 | laminin, gamma 2 | 0.0318937 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0308293 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.030478 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0297371 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0294392 |
| MSN | moesin | 0.0291627 |
| AREG | amphiregulin | 0.0291564 |
| FAM107B | family with sequence similarity 107, member B | 0.0285775 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.028572 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281442 |
| VEGFA | vascular endothelial growth factor A | 0.028051 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0272892 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0271951 |
| LAMB1 | laminin, beta 1 | 0.0265933 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0265819 |
| MCL1 | myeloid cell leukemia 1 | 0.024831 |
| SMAD3 | SMAD family member 3 | 0.0246898 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0241962 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0240916 |
| RPL3 | ribosomal protein L3 | 0.0232463 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0230876 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0230718 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0226765 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0220687 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0218225 |
| MYO5B | myosin VB | 0.0217191 |
| SET | SET nuclear proto-oncogene | 0.021608 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0213494 |
| CANX | calnexin | 0.0213242 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0212564 |
| HYOU1 | hypoxia up-regulated 1 | 0.0210592 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0206033 |
| NUP58 | nucleoporin 58 | 0.0204387 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0202696 |
| APP | amyloid beta (A4) precursor protein | 0.020082 |
| ADM | adrenomedullin | 0.0197826 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0197242 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0196149 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0188598 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0188136 |
| OGA | O-GlcNAcase | 0.0185654 |
| SRP54 | signal recognition particle 54kDa | 0.0184923 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0183994 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0182877 |
| CCNL1 | cyclin L1 | 0.017897 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0178855 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0177763 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0176748 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0176732 |
| HKDC1 | hexokinase domain containing 1 | 0.0175751 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0174504 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0174408 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0174024 |
| JAK1 | Janus kinase 1 | 0.017341 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0173373 |
| OPTN | optineurin | 0.0172006 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0170331 |
| YTHDC1 | YTH domain containing 1 | 0.0169126 |
| PCBP2 | poly(rC) binding protein 2 | 0.0168631 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0168573 |
| TMF1 | TATA element modulatory factor 1 | 0.0168382 |
| DSPP | dentin sialophosphoprotein | 0.0164851 |
| CDCP1 | CUB domain containing protein 1 | 0.0163271 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0161477 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0161269 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0160199 |
| TUFT1 | tuftelin 1 | 0.0159304 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0156761 |
| CAPRIN2 | caprin family member 2 | 0.0156122 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0155871 |
| BARX2 | BARX homeobox 2 | 0.0155836 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0154717 |
| RPS18 | ribosomal protein S18 | 0.0153418 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0150822 |
| TXNIP | thioredoxin interacting protein | 0.0147918 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0147453 |
| SPAG9 | sperm associated antigen 9 | 0.0147309 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0146352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.22762 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.190826 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.158166 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.142953 |
| CP | ceruloplasmin (ferroxidase) | -0.123367 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111993 |
| MMP7 | matrix metallopeptidase 7 | -0.0977296 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0937113 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0813168 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0783134 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0773641 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0745963 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0745649 |
| ANXA2 | annexin A2 | -0.0733281 |
| KRT19 | keratin 19, type I | -0.0731199 |
| EHBP1 | EH domain binding protein 1 | -0.0706239 |
| EFNA5 | ephrin-A5 | -0.0665811 |
| HLA-B | major histocompatibility complex, class I, B | -0.0658951 |
| ENO1 | enolase 1, (alpha) | -0.0650038 |
| VIM | vimentin | -0.0644655 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0636881 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0634339 |
| S100A6 | S100 calcium binding protein A6 | -0.0618373 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0609753 |
| RPL35A | ribosomal protein L35a | -0.058208 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0578429 |
| PGK1 | phosphoglycerate kinase 1 | -0.0542415 |
| HMGA1 | high mobility group AT-hook 1 | -0.0510751 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0494605 |
| RAD51B | RAD51 paralog B | -0.0481796 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0478775 |
| HLA-A | major histocompatibility complex, class I, A | -0.0468077 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.04564 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0446387 |
| MUC4 | mucin 4, cell surface associated | -0.043657 |
| SP100 | SP100 nuclear antigen | -0.0432264 |
| RPL23 | ribosomal protein L23 | -0.0426149 |
| FTL | ferritin, light polypeptide | -0.0421985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0417681 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0414841 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0405927 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405894 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0404412 |
| B2M | beta-2-microglobulin | -0.0399612 |
| NCKAP5 | NCK-associated protein 5 | -0.0399316 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0395055 |
| CD2AP | CD2-associated protein | -0.0393099 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.03916 |
| TMSB4X | thymosin beta 4, X-linked | -0.0388167 |
| GNAS | GNAS complex locus | -0.0376387 |
| LCN2 | lipocalin 2 | -0.0371081 |
| HLA-E | major histocompatibility complex, class I, E | -0.0365121 |
| PKM | pyruvate kinase, muscle | -0.0362176 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0361012 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360163 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0353653 |
| RPL34 | ribosomal protein L34 | -0.0346188 |
| LASP1 | LIM and SH3 protein 1 | -0.0344475 |
| TAPBP | TAP binding protein (tapasin) | -0.0342975 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0337808 |
| OSMR | oncostatin M receptor | -0.0336636 |
| NDRG1 | N-myc downstream regulated 1 | -0.0334259 |
| RPS24 | ribosomal protein S24 | -0.0333061 |
| ANXA4 | annexin A4 | -0.0332772 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0331673 |
| LAMB3 | laminin, beta 3 | -0.0327393 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0325646 |
| PTMA | prothymosin, alpha | -0.0324776 |
| FAM162A | family with sequence similarity 162, member A | -0.0322179 |
| MCU | mitochondrial calcium uniporter | -0.032092 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0318392 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0309407 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0307653 |
| C3 | complement component 3 | -0.030417 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0303426 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0300443 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0300034 |
| EGR1 | early growth response 1 | -0.0299427 |
| MUC16 | mucin 16, cell surface associated | -0.0296547 |
| MT1X | metallothionein 1X | -0.0288929 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279079 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0278995 |
| NRG1 | neuregulin 1 | -0.0276391 |
| LDHA | lactate dehydrogenase A | -0.0274613 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0273814 |
| CD47 | CD47 molecule | -0.0272265 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0270645 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0270502 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0268506 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0268217 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0267532 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0266441 |
| RASAL2 | RAS protein activator like 2 | -0.026595 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0265473 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0263969 |
| CDK6 | cyclin-dependent kinase 6 | -0.0262194 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.026049 |
| TUBB | tubulin, beta class I | -0.0259442 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.02592 |
| H1-0 | H1.0 linker histone | -0.0258671 |
